Mouse Monoclonal Antibody to Dynamin-1 | ProMab 20072 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to Dynamin-1

catalog :

20072

quantity :

100µl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3G4B6

The same clone is also sold as:

Invitrogen: MA5-15285
Santa Cruz Biotechnology: sc-53877
Cell Signaling Technology: 4565
Novus Biologicals: NB110-60491
OriGene: TA336537
Abnova: MAB8301

reactivity :

human

application :

western blot, ELISA, immunohistochemistry

product information

Catalog :

20072

Title :

Mouse Monoclonal Antibody to Dynamin-1

Species :

Human

Clone :

3G4B6;

lsotype :

Mouse IgG2a

Size :

100µl

Storage :

4?; -20? for long term storage

Description :

Dynamin-1 (Dyn1), with 864-amino acid protein (about 95kDa), belongs to the dynamin family. Dynamin-1 (neuron-specific), dynamin-2 (ubiquitously expressed), and dynamin-3 (expressed only in the testis, brain, and lung), constitute the dynamin family. Members of the dynamin family are GPTase, microtubule-associated proteins which are involved in endocytosis, synaptic transmission and neurogenesis. Dynamin-1 is phosphorylated in nerve terminals exclusively in the cytosolic compartment and in vitro by protein kinase C. Dynamin-1 is a large GTPase enzyme required in membrane constriction and fission during multiple forms of endocytosis. Dynamin-1 is also a key molecule required for the recycling of synaptic vesicles in neurons, and it has been known that dynamin-1 gene expression is induced during neuronal differentiation.

Immunogen :

Purified recombinant fragment of human Dynamin-1 expressed in E. Coli.

Formulation :

Ascitic fluid containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000

References :

1. Annie Quan and Phillip J. Robinson. Methods Enzymol. 2005; 404:556-69. ; 2. Jiyun Yoo, Moon-Jin Jeong, Byoung-Mog Kwon. J. Biol. Chem., Mar 2002; 277: 11904 – 11909 ;

Type :

Monoclonal Antibody

MW :

97kDa

Aliases :

DNM; DNM1