Mouse Monoclonal Antibody to EphA2 | ProMab 20071 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to EphA2

catalog :

20071

quantity :

100µl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1B3C7

The same clone is also sold as:

Abnova: MAB10635
OriGene: AM06122SU-N
Invitrogen: MA5-15284

reactivity :

human

application :

western blot, ELISA, immunohistochemistry

product information

Catalog :

20071

Title :

Mouse Monoclonal Antibody to EphA2

Species :

Human

Clone :

1B3C7;

lsotype :

Mouse IgM

Size :

100µl

Storage :

4?; -20? for long term storage

Description :

EPH receptor A2 (EphA2), with 976-amino acid protein (about 107 kDa), belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EphA1, EphA2, EphA3, EphA4, EphA5, EphA6, EphA7, EphA8, EphA10, EphB1, EphB2, EphB3, EphB4 and EphB6 are Eph family receptors for Ephrin family ligands. In normal cells, EphA2 negatively regulates cell growth and invasiveness. EphA2 is overexpressed by many human cancers, and is often associated with poor prognostic features. The clinical significance of the expression of EphA2 was observed in breast, prostate, colon, skin, cervical, ovarian, and lung cancers.EphA2 may serve as a novel target for bladder cancer, colonic adenocarcinoma and ovarian cancer therapy.

Immunogen :

Purified recombinant fragment of EphA2 expressed in E. Coli.

Formulation :

Ascitic fluid containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000

References :

1. Shaji Abraham, Deborah W. Knapp, Liang Cheng. Clin Cancer Res. 2006 Jan 15;12(2):353-60. ; 2. Charles N Landen, Michael S Kinch, Anil K Sood. Expert Opin Ther Targets. 2005 Dec;9(6):1179-87. ;

Type :

Monoclonal Antibody

Aliases :

ECK; EPHA2