Mouse Monoclonal Antibody to FAK | ProMab 20065 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to FAK

catalog :

20065

quantity :

100µl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

4A9D6

The same clone is also sold as:

Invitrogen: MA5-15282
OriGene: AM06120SU-N
MyBioSource: MBS850860

reactivity :

human

application :

western blot, ELISA

product information

Catalog :

20065

Title :

Mouse Monoclonal Antibody to FAK

Species :

Human

Clone :

4A9D6;

Size :

100µl

Storage :

4?; -20? for long term storage

Description :

Focal adhesion kinase(FAK), with 1074 -amino acid protein(about 118 kDa), is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. FAK is concentrated at the basal edge of only basal keratinocytes that are actively migrating and rapidly proliferating in repairing burn wounds, and is activated and localized to the focal adhesions of spreading keratinocytes in culture. Thus, it has been postulated that FAK may have an important in vivo role in the re-epithelialization of human wounds. FAK protein tyrosine kinase activity has also been shown to increase in cells stimulated to grow by use of mitogenic neuropeptides or neurotransmitters acting through G protein-coupled receptors.

Immunogen :

Purified recombinant fragment of FAK expressed in E. Coli.

Formulation :

Ascitic fluid containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000

References :

1. Madeleine Toutant, Jeanne-Marie Studler, et al.Mol. Cell. Biol., Nov 2002; 22: 7731 - 7743. ; 2. Danshan Huang, Anthony T. Cheung, et al. J. Biol. Chem, May 2002; 277: 18151 – 18160. ;

Type :

Monoclonal Antibody

Aliases :

FAK; FADK; FAK1; pp125FAK; PTK2