This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
ProMab
product type :
antibody
product name :
Mouse Monoclonal Antibody to LAL
catalog :
20061
quantity :
100µl
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
9G7F12

The same clone is also sold as:
reactivity :
human
application :
western blot, ELISA
product information
Catalog :
20061
Title :
Mouse Monoclonal Antibody to LAL
Species :
Human
Clone :
9G7F12;
lsotype :
Mouse IgG2a
Size :
100µl
Storage :
4?; -20? for long term storage
Description :
Lysosomal acid lipase (LAL), with 378-amino acid protein( 43-54 kDa), functions in the lysosome to catalyze the hydrolysis of cholesteryl esters and triglycerides which are taken up by receptor-mediated endocytosis. An inherited deficiency or low activity of human lysosomal acid lipase results in the intralysosomal storage of the respective lipid substrates. So it is also responsible for the rare conditions of Wolman disease and cholesteryl ester storage disease (CESD). As the enzyme is synthesized by all nucleated cells, lipid-laden cells are found in all organs, particularly in liver, spleen, the adrenal and the hemopoietic system, and in the intestine as well as in the lymph nodes, lungs, testes, and ovaries.
Immunogen :
Purified recombinant fragment of LAL expressed in E. Coli.
Formulation :
Purified antibody in PBS containing 0.03% sodium azide.
Applications :
ELISA: 1/10000; WB: 1/500 - 1/2000
References :
1. Uta Drebber, Matthias Andersen, Hans U Kasper, et al, World J Gastroenterol. 2005 Apr 21;11(15):2364-6. ; 2. Renata Boldrini, Rita Devito, R.Biselli,et al, Pathol Res Pract. 2004;200(3):231-40. ;
Type :
Monoclonal Antibody
Aliases :
LAL; CESD; LIPA
company information
ProMab
5221 Central Avenue, Suite 200
Richmond, CA 94804
info@promab.com
http://www.promab.com
1-866-339-0871
headquarters: USA