Mouse Monoclonal Antibody to HPRT | ProMab 20056 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to HPRT

catalog :

20056

quantity :

100µl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1F8D11

The same clone is also sold as:

Invitrogen: MA5-15274

reactivity :

human

application :

western blot, ELISA

product information

Catalog :

20056

Title :

Mouse Monoclonal Antibody to HPRT

Species :

Human

Clone :

1F8D11;

lsotype :

Mouse IgG2b

Size :

100µl

Storage :

4?; -20? for long term storage

Description :

The HPRT1 gene provides instructions for making an enzyme called hypoxanthine phosphoribosyltransferase 1. This enzyme allows cells to recycle purines, some of the building blocks of DNA and its chemical cousin RNA.The enzyme hypoxanthine-guanine phosphoribosyltrasferase (E.C.2.4.2.8., HPRT) plays a crucial role in uric acid synthesis and purine metabolism.This enzyme catalyzes the conversion of hypoxanthine and guanine to inosine monophosphate (IMP) and guanosine monophosphate (GMP), respectively, and uses phosphoribosylpyrophosphate (PRPP) as a cosubstrate and as a source of energy . This pathway is also known as the purine salvage pathway because it allows cells to reuse purine compounds to build DNA and RNA.

Immunogen :

Purified recombinant fragment of HPRT expressed in E. Coli.

Formulation :

Ascitic fluid containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000

References :

1. Manjanatha MG, et.al Mutat Res. 2004 Mar 22;547(1-2):5-18.

Type :

Monoclonal Antibody