Mouse Monoclonal Antibody to Mouse TUG | ProMab 20048 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to Mouse TUG

catalog :

20048

quantity :

100µl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

4A11A6G11

The same clone is also sold as:

Santa Cruz Biotechnology: sc-53952
Invitrogen: MA5-15269
Abnova: MAB5537

reactivity :

human, mouse

application :

western blot, ELISA

product information

Catalog :

20048

Title :

Mouse Monoclonal Antibody to Mouse TUG

Species :

Mouse

Clone :

4A11A6G11;

lsotype :

Mouse IgG1

Size :

100µl

Storage :

4?; -20? for long term storage

Description :

The TUG protein contains a UBX domain, for GLUT4. In truncated form, TUG acts in a dominant-negative manner to inhibit insulin-stimulated GLUT4 redistribution in Chinese hamster ovary cells and 3T3-L1 adipocytes. Full-length TUG forms a complex specifically with GLUT4. In 3T3-L1 adipocytes, this complex is present in unstimulated cells and is largely disassembled by insulin. Endogenous TUG is localized with the insulin-mobilizable pool of GLUT4 in unstimulated 3T3-L1 adipocytes, and is not mobilized to the plasma membrane by insulin.

Immunogen :

Purified recombinant fragment of TUG expressed in E. Coli.

Formulation :

Purified antibody in PBS containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000

References :

1. Nature 2003,425:727 - 733. ;

Type :

Monoclonal Antibody

Aliases :

ASPCR1, ASPL, ASPS, RCC17, TUG, UBXD9, UBXN9