Mouse Monoclonal Antibody to KSHV ORF8 | ProMab 20043 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to KSHV ORF8

catalog :

20043

quantity :

100µl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

N/A

reactivity :

Human gammaherpesvirus 8

application :

western blot, ELISA

product information

Catalog :

20043

Title :

Mouse Monoclonal Antibody to KSHV ORF8

Species :

Human;

Clone :

N/A;

Size :

100µl

Storage :

4?; -20? for long term storage

Description :

Kaposi's sarcoma-associated herpesvirus (KSHV) belongs to the gamma-(2)-herpesvirus subfamily and has been closely linked to the Kaposi’s sarcoma, primary effusion lymphoma (PEL) and multicentric Castleman’s disease. The genome of KSHV is 165-170 kb and contains at least 88 open reading frames. KSHV ORF8 is a virion envelope-associated protein. Akula et al (2003) report it acts as a Glycoprotein B mediated signaling during virus entry. This Glycoprotein possesses the Arg-Gly-Asp (RGD) motif and utilizes alpha3beta1 integrin as one of the receptors for its entry into the target cells.

Immunogen :

Synthetic peptide, corresponding to amino acids sequence of KSHV ORF8. ;

Formulation :

Rabbit anti-serum.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000

References :

1. James J. Proc. Natl. Acad. Sci Vol. 1993, pp. 14862-14867. ; 2. Wang FZ. J Virol. 2003 Mar; 77(5):3131-47. ;

Type :

Monoclonal Antibody

Aliases :

ORF8