Mouse Monoclonal Antibody to GAPDH | ProMab 20035 product information

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to GAPDH

catalog :

20035

quantity :

100µl

price :

198.00 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1.A.10

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry

more info or order :

ProMab product webpage

citations: 2

Reference
Wang S, Hannafon B, Wolf R, Zhou J, Avery J, Wu J, et al. Characterization of docosahexaenoic acid (DHA)-induced heme oxygenase-1 (HO-1) expression in human cancer cells: the importance of enhanced BTB and CNC homology 1 (Bach1) degradation. J Nutr Biochem. 2014;25:515-25 pubmed publisher
Wang S, Hannafon B, Zhou J, Ding W. Clofibrate induces heme oxygenase 1 expression through a PPARα-independent mechanism in human cancer cells. Cell Physiol Biochem. 2013;32:1255-64 pubmed publisher

product information

Catalog :

20035

Title :

Mouse Monoclonal Antibody to GAPDH

Species :

Human

Clone :

1A10;

lsotype :

Mouse IgG1

Size :

100µl

Storage :

4?; -20? for long term storage

Description :

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is well known as one of the key enzymes involved in glycolysis. It catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The enzyme exists as a tetramer of identical chains. Besides its functioning as a glycolytic enzyme in cytoplasm, recent evidence suggest that mammalian GAPDH is also involved in a great number of intracellular proceses such as membrane fusion, microtubule bundling, phosphotransferase activity, nuclear RNA export, DNA replication, and DNA repair. During the last decade a lot of findings appeared concerning the role of GAPDH in different pathologies including prostate cancer progression, programmed neuronal cell death, age- related neuronal diseases, such as Alzheimer’s and Huntington’s disease.

Immunogen :

Purified recombinant fragment of human GAPDH expressed in E. Coli. ;

Formulation :

Ascitic fluid containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000

References :

1. Allen R.W. J. Biol. Chem. 1987.262:649-653. ; 2. Sumner CJ. Ann Neurol 2003.54:6 47-54. ;

List Price (USD) :

198.00 USD

Type :

Monoclonal Antibody

MW :

37kDa

Aliases :

G3PD; GAPD; MGC88685

more info or order :

ProMab product webpage