This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
ProMab
product type :
antibody
product name :
Mouse Monoclonal Antibody to CHK1
catalog :
20031
quantity :
100µl
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2G1D5

The same clone is also sold as:
reactivity :
human, mouse
application :
western blot, ELISA
product information
Catalog :
20031
Title :
Mouse Monoclonal Antibody to CHK1
Species :
Human, Mouse
Clone :
2G1D5;
lsotype :
Mouse IgG1
Size :
100µl
Storage :
4?; -20? for long term storage
Description :
CHK1, also known as CHEK1, it is a kinase that phosphorylates cdc25, an important phosphatase in cell cycle control, particularly for entry into mitosis. Cdc25, when phosphorylated on serine 216 by chk1 becomes bound by an adaptor protein in the cytoplasm. Therefore it is inhibited from removing the inhibiting phosphate from MPF (mitotic/maturation promoting factor) added by Wee1. Consequently, a cell is prevented from entering mitosis. Chk1 can also phosphorylate p53 at Ser20 in vitro.
Immunogen :
Purified recombinant fragment of CHK1 expressed in E. Coli.
Formulation :
Purified antibody in PBS containing 0.03% sodium azide.
Applications :
ELISA: 1/10000; WB: 1/500 - 1/2000
References :
1. EMBO J. 1998. 16: 545-554. ; 2. Science 1998. 282: 1893-1897.
Type :
Monoclonal Antibody
MW :
56kDa
Aliases :
CHEK1
company information
ProMab
5221 Central Avenue, Suite 200
Richmond, CA 94804
info@promab.com
http://www.promab.com
1-866-339-0871
headquarters: USA