This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
ProMab
product type :
antibody
product name :
Mouse Monoclonal Antibody to MCP-1
catalog :
20014
quantity :
100µl
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
1A7B8

The same clone is also sold as:
reactivity :
human
application :
western blot, ELISA
product information
Catalog :
20014
Title :
Mouse Monoclonal Antibody to MCP-1
Species :
human
Clone :
1A7B8;
lsotype :
Mouse IgG1.kappa
Size :
100µl
Storage :
4?; -20? for long term storage
Description :
Monocyte chemoattractant protein-1 (MCP-1) is a member of the chemokine-beta family of cytokines. The protein is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. It may play a inprotant role in the initiation and/or progression of pulmonary hypertension (PH). Blockade of a systemic MCP-1 signal pathway in vivo may prevent PH.
Immunogen :
Purified recombinant fragment of human MCP-1 expressed in E. Coli.
Formulation :
Purified antibody in PBS containing 0.03% sodium azide.
Applications :
ELISA: 1/10000; WB: 1/500 - 1/2000
References :
1. Yoshimura T. et al. 1989. FEBS Lett. 244:487-493. ; 2. Yoshimura T. et al. 1991. Adv. Exp. Med. Biol. 305:47-56. ; 3. Rollins B.J. et al. 1991. Genomics. 10:489-492. ;
Type :
Monoclonal Antibody
Aliases :
MCP1
company information
ProMab
5221 Central Avenue, Suite 200
Richmond, CA 94804
info@promab.com
http://www.promab.com
1-866-339-0871
headquarters: USA