Mouse Monoclonal Antibody to IL-10 | ProMab 20011 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to IL-10

catalog :

20011

quantity :

100µl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3C12C12

The same clone is also sold as:

OriGene: AM06081PU-N
Santa Cruz Biotechnology: sc-32815
Abnova: MAB8311

reactivity :

human

application :

western blot, ELISA

product information

Catalog :

20011

Title :

Mouse Monoclonal Antibody to IL-10

Species :

Human

Clone :

3C12C12;

lsotype :

Mouse IgG1

Size :

100µl

Storage :

4?; -20? for long term storage

Description :

Interleukine 10 (IL-10) is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down- regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.

Immunogen :

Purified recombinant fragment of human IL-10 expressed in E. Coli.

Formulation :

Purified antibody in PBS containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000

References :

1. Vieira P, et al. PNAS, 1991.88:1172-1176.

Type :

Monoclonal Antibody

Aliases :

IL10