Mouse Monoclonal Antibody to IFN-gamma | ProMab 20009 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to IFN-gamma

catalog :

20009

quantity :

100µl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3F1E3

The same clone is also sold as:

OriGene: AM06079PU-N
Abnova: MAB8310
Invitrogen: MA5-14762
Cell Signaling Technology: 3159
Santa Cruz Biotechnology: sc-32813

reactivity :

human

application :

western blot, ELISA

product information

Catalog :

20009

Title :

Mouse Monoclonal Antibody to IFN-gamma

Species :

Human;

Clone :

3F1E3;

lsotype :

Mouse IgG1

Size :

100µl

Storage :

4?; -20? for long term storage

Description :

Interferon-? (IFN-?) is a pro-inflammatory cytokine that is central in host resistance to infection. It is mainly produced by natural killer cells and CD4+ and CD8+ T cells, its receptors are found on nearly all cells, where it activates diverse responses that enable potential host cells to prevent invasive infection by bacteria, parasites and viruses. Takayanagi et al. (2000) demonstrated that IFN-? strongly suppresses osteoclastogenesis by interfering with the RANKL (602642)-RANK (603499) signaling pathway. Tsubota et al. (1999) reported that this upregulation in Sjogren syndrome patients may be controlled by interferon-gamma through the activation of transcription factor NFKB

Immunogen :

Purified recombinant fragment of human IFN-? expressed in E. Coli.

Formulation :

Purified antibody in PBS containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000

References :

1. Takayanagi, H. et al. Nature 2000. 408: 600-605. ; 2. Tsubota, K. et al. Invest. Ophthal. Vis. Sci. 40: 28-34, 1999.

Type :

Monoclonal Antibody

MW :

19.3kDa

Aliases :

IFG; IFI