LGR5 Mouse Monoclonal Antibody [Clone ID: OTI2A2] | OriGene TA503316 product information

product summary

company name :

OriGene

product type :

antibody

product name :

LGR5 Mouse Monoclonal Antibody [Clone ID: OTI2A2]

catalog :

TA503316

quantity :

100 µl

price :

478 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

OTI2A2

reactivity :

hamsters, African green monkey, human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section

more info or order :

OriGene product webpage

citations: 18

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; human; loading ...; fig 1d western blot; human; loading ...; fig 1a	Vazquez Iglesias L, Barcia Castro L, Rodríguez Quiroga M, Páez de la Cadena M, Rodríguez Berrocal J, Cordero O. Surface expression marker profile in colon cancer cell lines and sphere-derived cells suggests complexity in CD26+ cancer stem cells subsets. Biol Open. 2019;8: pubmed publisher
immunocytochemistry; human; 1:400; fig 9	Wang B, Chen Q, Cao Y, Ma X, Yin C, Jia Y, et al. LGR5 Is a Gastric Cancer Stem Cell Marker Associated with Stemness and the EMT Signature Genes NANOG, NANOGP8, PRRX1, TWIST1, and BMI1. PLoS ONE. 2016;11:e0168904 pubmed publisher
immunocytochemistry; human; fig s1b immunohistochemistry; human; loading ...; fig s5	Chen H, Wei Z, Sun J, Bhattacharya A, Savage D, Serda R, et al. A recellularized human colon model identifies cancer driver genes. Nat Biotechnol. 2016;34:845-51 pubmed publisher
western blot; mouse; 1:2000; loading ...; fig 1 western blot; hamsters; 1:2000; loading ...; fig 1 western blot; human; 1:2000; loading ...; fig 1 western blot; African green monkey; 1:2000; loading ...; fig 1	Alizadeh Navaei R, Rafiei A, Abedian Kenari S, Asgarian Omran H, Valadan R, Hedayatizadeh Omran A. Comparison of leucine-rich repeat-containing G protein-coupled receptor 5 expression in different cancer and normal cell lines. Biomed Rep. 2016;5:130-132 pubmed
immunohistochemistry - paraffin section; human; 1:300; fig s2	Shaikh L, Zhou J, Teo A, Garg S, Neogi S, Figg N, et al. LGR5 Activates Noncanonical Wnt Signaling and Inhibits Aldosterone Production in the Human Adrenal. J Clin Endocrinol Metab. 2015;100:E836-44 pubmed publisher
western blot; human; 1:1000; fig 2	Sharon C, Baranwal S, Patel N, Rodriguez Agudo D, Pandak W, Majumdar A, et al. Inhibition of insulin-like growth factor receptor/AKT/mammalian target of rapamycin axis targets colorectal cancer stem cells by attenuating mevalonate-isoprenoid pathway in vitro and in vivo. Oncotarget. 2015;6:15332-47 pubmed
immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 5 western blot; human; 1:500; loading ...; fig 3d	Hsu H, Liu Y, Tseng K, Yang T, Yeh C, You J, et al. CBB1003, a lysine-specific demethylase 1 inhibitor, suppresses colorectal cancer cells growth through down-regulation of leucine-rich repeat-containing G-protein-coupled receptor 5 expression. J Cancer Res Clin Oncol. 2015;141:11-21 pubmed publisher
western blot; human; 1:500	Hsu H, Liu Y, Tseng K, Tan B, Chen S, Chen H. LGR5 regulates survival through mitochondria-mediated apoptosis and by targeting the Wnt/?-catenin signaling pathway in colorectal cancer cells. Cell Signal. 2014;26:2333-42 pubmed publisher
	Liu R, Moriggl R, Zhang D, Li H, Karns R, Ruan H, et al. Constitutive STAT5 activation regulates Paneth and Paneth-like cells to control Clostridium difficile colitis. Life Sci Alliance. 2019;2: pubmed publisher
	Granofszky N, Lang M, Khare V, Schmid G, Scharl T, Ferk F, et al. Identification of PMN-released Mutagenic Factors in a Co-culture Model for Colitis-associated Cancer. Carcinogenesis. 2017;: pubmed publisher
	Yang Q, Bavi P, Wang J, Roehrl M. Immuno-proteomic discovery of tumor tissue autoantigens identifies olfactomedin 4, CD11b, and integrin alpha-2 as markers of colorectal cancer with liver metastases. J Proteomics. 2017;168:53-65 pubmed publisher
	Patel N, Sharon C, Baranwal S, Boothello R, Desai U, Patel B. Heparan sulfate hexasaccharide selectively inhibits cancer stem cells self-renewal by activating p38 MAP kinase. Oncotarget. 2016;7:84608-84622 pubmed publisher
	Osawa H, Takahashi H, Nishimura J, Ohta K, Haraguchi N, Hata T, et al. Full-length LGR5-positive cells have chemoresistant characteristics in colorectal cancer. Br J Cancer. 2016;114:1251-60 pubmed publisher
	Xi H, Cai A, Wu X, Cui J, Shen W, Bian S, et al. Leucine-rich repeat-containing G-protein-coupled receptor 5 is associated with invasion, metastasis, and could be a potential therapeutic target in human gastric cancer. Br J Cancer. 2014;110:2011-20 pubmed publisher
	Wang J, Guo X, Lui M, Chu P, Yoo J, Chang M, et al. Identification of a distinct small cell population from human bone marrow reveals its multipotency in vivo and in vitro. PLoS ONE. 2014;9:e85112 pubmed publisher
	Jiang N, Zhou J, Chen M, Schiff M, Lee C, Kong K, et al. Postnatal epithelium and mesenchyme stem/progenitor cells in bioengineered amelogenesis and dentinogenesis. Biomaterials. 2014;35:2172-80 pubmed publisher
	Wu C, Xie Y, Gao F, Wang Y, Guo Y, Tian H, et al. Lgr5 expression as stem cell marker in human gastric gland and its relatedness with other putative cancer stem cell markers. Gene. 2013;525:18-25 pubmed publisher
	Pastò A, Marchesi M, Diamantini A, Frasson C, Curtarello M, Lago C, et al. PKH26 staining defines distinct subsets of normal human colon epithelial cells at different maturation stages. PLoS ONE. 2012;7:e43379 pubmed publisher

product information

SKU :

TA503316

Category :

Antibodies

Sub-Category :

Primary Antibodies

Name :

LGR5 Mouse Monoclonal Antibody [Clone ID: OTI2A2]

Description :

LGR5 mouse monoclonal antibody, clone OTI2A2

Size :

100 µl

Price US :

478 USD

Delivery Time US :

In Stock

Symbol :

LGR5

Accn :

NM_003667

Clonality :

Monoclonal

Clone Name :

OTI2A2

Host :

Mouse

Isotype :

IgG1

Applications :

FC, IF, IHC, IP, WB

Reactivity :

Human, Mouse, Rat

more info or order :

OriGene product webpage