product summary
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company name :
OriGene
product type :
antibody
product name :
Clone OTI4C5, Anti-DDK (FLAG) monoclonal antibody
catalog :
TA50011-100
quantity :
100 µl
price :
412 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
OTI4C5 (formerly 4C5)
reactivity :
human, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry
more info or order :
citations: 91
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; loading ...; fig 4f
Wei R, Lin S, Wu W, Chen L, Li C, Chen H, et al. A microtubule inhibitor, ABT-751, induces autophagy and delays apoptosis in Huh-7 cells. Toxicol Appl Pharmacol. 2016;311:88-98 pubmed publisher
  • immunocytochemistry; rat; fig 8
Lim S, Jin L, Jin J, Yang C. Effect of Exendin-4 on Autophagy Clearance in Beta Cell of Rats with Tacrolimus-induced Diabetes Mellitus. Sci Rep. 2016;6:29921 pubmed publisher
  • immunocytochemistry; human; fig 2
Nudel R. An investigation of NFXL1, a gene implicated in a study of specific language impairment. J Neurodev Disord. 2016;8:13 pubmed publisher
  • western blot; human; fig 4
Kimball S, Gordon B, Moyer J, Dennis M, Jefferson L. Leucine induced dephosphorylation of Sestrin2 promotes mTORC1 activation. Cell Signal. 2016;28:896-906 pubmed publisher
  • immunoprecipitation; human; fig 5f
  • western blot; human; fig 5f
Hung M, Chen Y, Chu P, Shih C, Yu H, Tai W, et al. Upregulation of the oncoprotein SET determines poor clinical outcomes in hepatocellular carcinoma and shows therapeutic potential. Oncogene. 2016;35:4891-902 pubmed publisher
  • immunoprecipitation; human; fig 4
Ljungström V, Cortese D, Young E, Pandzic T, Mansouri L, Plevova K, et al. Whole-exome sequencing in relapsing chronic lymphocytic leukemia: clinical impact of recurrent RPS15 mutations. Blood. 2016;127:1007-16 pubmed publisher
Mozzi A, Biolatti M, Cagliani R, Forni D, Dell Oste V, Pontremoli C, et al. Past and ongoing adaptation of human cytomegalovirus to its host. PLoS Pathog. 2020;16:e1008476 pubmed publisher
Lee S, Kieu C, Martin C, Han J, Chen W, Kim J, et al. NFATc3 plays an oncogenic role in oral/oropharyngeal squamous cell carcinomas by promoting cancer stemness via expression of OCT4. Oncotarget. 2019;10:2306-2319 pubmed publisher
Xiao G, Mohanakrishnan A, Schmid S. Role for ERK1/2-dependent activation of FCHSD2 in cancer cell-selective regulation of clathrin-mediated endocytosis. Proc Natl Acad Sci U S A. 2018;115:E9570-E9579 pubmed publisher
Chu T, Connell M, Zhou L, He Z, Won J, Chen H, et al. Cell Cycle-Dependent Tumor Engraftment and Migration Are Enabled by Aurora-A. Mol Cancer Res. 2018;16:16-31 pubmed publisher
Iida Y, Ciechanover A, Marzese D, Hata K, Bustos M, Ono S, et al. Epigenetic Regulation of KPC1 Ubiquitin Ligase Affects the NF-?B Pathway in Melanoma. Clin Cancer Res. 2017;23:4831-4842 pubmed publisher
Qi L, Zhou L, Lu M, Yuan K, Li Z, Wu G, et al. Development of a highly specific HER2 monoclonal antibody for immunohistochemistry using protein microarray chips. Biochem Biophys Res Commun. 2017;484:248-254 pubmed publisher
Skotte N, Sanders S, Singaraja R, Ehrnhoefer D, Vaid K, Qiu X, et al. Palmitoylation of caspase-6 by HIP14 regulates its activation. Cell Death Differ. 2017;24:433-444 pubmed publisher
Martin Almedina S, Martínez Corral I, Holdhus R, Vicente A, Fotiou E, Lin S, et al. EPHB4 kinase-inactivating mutations cause autosomal dominant lymphatic-related hydrops fetalis. J Clin Invest. 2016;126:3080-8 pubmed publisher
Wang S, Chu C, Guo M, Jiang L, Nie H, Zhang W, et al. Identification of a specific α-synuclein peptide (α-Syn 29-40) capable of eliciting microglial superoxide production to damage dopaminergic neurons. J Neuroinflammation. 2016;13:158 pubmed publisher
Ko S, Rho D, Jeon J, Kim Y, Woo H, Lee Y, et al. Bacteroides fragilis Enterotoxin Upregulates Heme Oxygenase-1 in Intestinal Epithelial Cells via a Mitogen-Activated Protein Kinase- and NF-?B-Dependent Pathway, Leading to Modulation of Apoptosis. Infect Immun. 2016;84:2541-54 pubmed publisher
Wang Y, Xu X, Pan M, Jin T. ELMO1 Directly Interacts with G?? Subunit to Transduce GPCR Signaling to Rac1 Activation in Chemotaxis. J Cancer. 2016;7:973-83 pubmed publisher
Mkhikian H, Mortales C, Zhou R, Khachikyan K, Wu G, Haslam S, et al. Golgi self-correction generates bioequivalent glycans to preserve cellular homeostasis. elife. 2016;5: pubmed publisher
Brichkina A, Nguyen N, Baskar R, Wee S, Gunaratne J, Robinson R, et al. Proline isomerisation as a novel regulatory mechanism for p38MAPK activation and functions. Cell Death Differ. 2016;23:1592-601 pubmed publisher
Hur H, Lee J, Yang S, Kim J, Park A, Kim M. HOXC9 Induces Phenotypic Switching between Proliferation and Invasion in Breast Cancer Cells. J Cancer. 2016;7:768-73 pubmed publisher
Sharma S, Patnaik S, Kemer Z, Baysal B. Transient overexpression of exogenous APOBEC3A causes C-to-U RNA editing of thousands of genes. RNA Biol. 2017;14:603-610 pubmed publisher
Edfeldt K, Hellman P, Westin G, Stalberg P. A plausible role for actin gamma smooth muscle 2 (ACTG2) in small intestinal neuroendocrine tumorigenesis. BMC Endocr Disord. 2016;16:19 pubmed publisher
Sudhaman S, Muthane U, Behari M, Govindappa S, Juyal R, Thelma B. Evidence of mutations in RIC3 acetylcholine receptor chaperone as a novel cause of autosomal-dominant Parkinson's disease with non-motor phenotypes. J Med Genet. 2016;53:559-66 pubmed publisher
Xu X, Tan X, Hulshoff M, Wilhelmi T, Zeisberg M, Zeisberg E. Hypoxia-induced endothelial-mesenchymal transition is associated with RASAL1 promoter hypermethylation in human coronary endothelial cells. FEBS Lett. 2016;590:1222-33 pubmed publisher
Kim M, Park Y, Nho Y, Yun S, Kim Y, Jung E, et al. Emodin isolated from Polygoni Multiflori Ramulus inhibits melanogenesis through the liver X receptor-mediated pathway. Chem Biol Interact. 2016;250:78-84 pubmed publisher
Lin X, Barravecchia M, Kothari P, Young J, Dean D. β1-Na(+),K(+)-ATPase gene therapy upregulates tight junctions to rescue lipopolysaccharide-induced acute lung injury. Gene Ther. 2016;23:489-99 pubmed publisher
Atanelishvili I, Shirai Y, Akter T, Buckner T, Noguchi A, Silver R, et al. M10, a caspase cleavage product of the hepatocyte growth factor receptor, interacts with Smad2 and demonstrates antifibrotic properties in vitro and in vivo. Transl Res. 2016;170:99-111 pubmed publisher
Emin M, Wang G, Castagna F, Rodriguez Lopez J, Wahab R, Wang J, et al. Increased internalization of complement inhibitor CD59 may contribute to endothelial inflammation in obstructive sleep apnea. Sci Transl Med. 2016;8:320ra1 pubmed publisher
Conley S, Bosco E, Tice D, Hollingsworth R, Herbst R, Xiao Z. HER2 drives Mucin-like 1 to control proliferation in breast cancer cells. Oncogene. 2016;35:4225-34 pubmed publisher
Wang X, Pan T. Methionine Mistranslation Bypasses the Restraint of the Genetic Code to Generate Mutant Proteins with Distinct Activities. PLoS Genet. 2015;11:e1005745 pubmed publisher
Dachineni R, Ai G, Kumar D, Sadhu S, Tummala H, Bhat G. Cyclin A2 and CDK2 as Novel Targets of Aspirin and Salicylic Acid: A Potential Role in Cancer Prevention. Mol Cancer Res. 2016;14:241-52 pubmed publisher
Hallmann K, Kudin A, Zsurka G, Kornblum C, Reimann J, Stüve B, et al. Loss of the smallest subunit of cytochrome c oxidase, COX8A, causes Leigh-like syndrome and epilepsy. Brain. 2016;139:338-45 pubmed publisher
Liu T, You H, Weng S, Wei Y, Eng H, Huang W. Recurrent Amplification at 13q34 Targets at CUL4A, IRS2, and TFDP1 As an Independent Adverse Prognosticator in Intrahepatic Cholangiocarcinoma. PLoS ONE. 2015;10:e0145388 pubmed publisher
Bhansali M, Zhou J, Shemshedini L. TM4SF3 and AR: A Nuclear Complex that Stabilizes Both Proteins. Mol Endocrinol. 2016;30:13-25 pubmed publisher
Daher R, Kannengiesser C, Houamel D, Lefebvre T, Bardou Jacquet E, Ducrot N, et al. Heterozygous Mutations in BMP6 Pro-peptide Lead to Inappropriate Hepcidin Synthesis and Moderate Iron Overload in Humans. Gastroenterology. 2016;150:672-683.e4 pubmed publisher
Kumar S, Parameswaran S, Sharma R. Novel myristoylation of the sperm-specific hexokinase 1 isoform regulates its atypical localization. Biol Open. 2015;4:1679-87 pubmed publisher
Yehia L, Niazi F, Ni Y, Ngeow J, Sankunny M, Liu Z, et al. Germline Heterozygous Variants in SEC23B Are Associated with Cowden Syndrome and Enriched in Apparently Sporadic Thyroid Cancer. Am J Hum Genet. 2015;97:661-76 pubmed publisher
Gavino C, Hamel N, Zeng J, Legault C, Guiot M, Chankowsky J, et al. Impaired RASGRF1/ERK-mediated GM-CSF response characterizes CARD9 deficiency in French-Canadians. J Allergy Clin Immunol. 2016;137:1178-1188.e7 pubmed publisher
Bertotti A, Papp E, Jones S, Adleff V, Anagnostou V, Lupo B, et al. The genomic landscape of response to EGFR blockade in colorectal cancer. Nature. 2015;526:263-7 pubmed publisher
Thiede Stan N, Tews B, Albrecht D, Ristic Z, Ewers H, Schwab M. Tetraspanin-3 is an organizer of the multi-subunit Nogo-A signaling complex. J Cell Sci. 2015;128:3583-96 pubmed publisher
Sun X, Li P, Zhu S, Cohen R, Marque L, Ross C, et al. Nuclear retention of full-length HTT RNA is mediated by splicing factors MBNL1 and U2AF65. Sci Rep. 2015;5:12521 pubmed publisher
Watt S, Purdie K, den Breems N, Dimon M, Arron S, McHugh A, et al. Novel CARD11 Mutations in Human Cutaneous Squamous Cell Carcinoma Lead to Aberrant NF-κB Regulation. Am J Pathol. 2015;185:2354-63 pubmed publisher
Sugatani T, Agapova O, Malluche H, Hruska K. SIRT6 deficiency culminates in low-turnover osteopenia. Bone. 2015;81:168-177 pubmed publisher
Erazo A, Goff S. Nuclear matrix protein Matrin 3 is a regulator of ZAP-mediated retroviral restriction. Retrovirology. 2015;12:57 pubmed publisher
Sarkar S, Jun S, Simpkins J. Estrogen amelioration of Aβ-induced defects in mitochondria is mediated by mitochondrial signaling pathway involving ERβ, AKAP and Drp1. Brain Res. 2015;1616:101-11 pubmed publisher
Pelin M, De Iudicibus S, Fusco L, Taboga E, Pellizzari G, Lagatolla C, et al. Role of oxidative stress mediated by glutathione-s-transferase in thiopurines' toxic effects. Chem Res Toxicol. 2015;28:1186-95 pubmed publisher
Méndez F, de Garay T, Rodríguez D, Rodríguez J. Infectious bursal disease virus VP5 polypeptide: a phosphoinositide-binding protein required for efficient cell-to-cell virus dissemination. PLoS ONE. 2015;10:e0123470 pubmed publisher
Nowyhed H, Huynh T, Blatchley A, Wu R, Thomas G, Hedrick C. The nuclear receptor nr4a1 controls CD8 T cell development through transcriptional suppression of runx3. Sci Rep. 2015;5:9059 pubmed publisher
Wang W, Zhang D, Wei Z, Wang Z, Bu X, Yang S, et al. Label-free detection microarray for novel peptide ligands screening base on MS-SPRi combination. Talanta. 2015;134:705-11 pubmed publisher
Wallert M, Hammes D, Nguyen T, Kiefer L, Berthelsen N, Kern A, et al. RhoA Kinase (Rock) and p90 Ribosomal S6 Kinase (p90Rsk) phosphorylation of the sodium hydrogen exchanger (NHE1) is required for lysophosphatidic acid-induced transport, cytoskeletal organization and migration. Cell Signal. 2015;27:498-509 pubmed publisher
Thompson J, Shuttleworth T. Anchoring protein AKAP79-mediated PKA phosphorylation of STIM1 determines selective activation of the ARC channel, a store-independent Orai channel. J Physiol. 2015;593:559-72 pubmed publisher
Yang T, Niu H, Chen L, Ku P, Lin K, Cheng J. Canavanine induces insulin release via activation of imidazoline I3 receptors. Clin Exp Pharmacol Physiol. 2015;42:263-8 pubmed publisher
Ge Y, Siegel A, Jordan R, Naumann C. Ligand binding alters dimerization and sequestering of urokinase receptors in raft-mimicking lipid mixtures. Biophys J. 2014;107:2101-11 pubmed publisher
Akhtar N, Makki M, Haqqi T. MicroRNA-602 and microRNA-608 regulate sonic hedgehog expression via target sites in the coding region in human chondrocytes. Arthritis Rheumatol. 2015;67:423-34 pubmed publisher
Agollah G, Gonzalez Garay M, Rasmussen J, Tan I, Aldrich M, Darne C, et al. Evidence for SH2 domain-containing 5'-inositol phosphatase-2 (SHIP2) contributing to a lymphatic dysfunction. PLoS ONE. 2014;9:e112548 pubmed publisher
Sun W, McCrory T, Khaw W, Petzing S, Myers T, Schmitt A. Matrix proteins of Nipah and Hendra viruses interact with beta subunits of AP-3 complexes. J Virol. 2014;88:13099-110 pubmed publisher
Kautz L, Jung G, Valore E, Rivella S, Nemeth E, Ganz T. Identification of erythroferrone as an erythroid regulator of iron metabolism. Nat Genet. 2014;46:678-84 pubmed publisher
Ball C, Rodriguez K, Stumpo D, Ribeiro Neto F, Korach K, Blackshear P, et al. The RNA-binding protein, ZFP36L2, influences ovulation and oocyte maturation. PLoS ONE. 2014;9:e97324 pubmed publisher
Guan R, Xu Y, Lei H, Gao Z, Xin Z, Guo Y. A novel protein is lower expressed in renal cell carcinoma. Int J Mol Sci. 2014;15:7398-408 pubmed publisher
Yang C, Hao J, Kong D, Cui X, Zhang W, Wang H, et al. ATM-mediated Mad1 Serine 214 phosphorylation regulates Mad1 dimerization and the spindle assembly checkpoint. Carcinogenesis. 2014;35:2007-13 pubmed publisher
Lazarova D, Chiaro C, Bordonaro M. Butyrate induced changes in Wnt-signaling specific gene expression in colorectal cancer cells. BMC Res Notes. 2014;7:226 pubmed publisher
Butland S, Sanders S, Schmidt M, Riechers S, Lin D, Martin D, et al. The palmitoyl acyltransferase HIP14 shares a high proportion of interactors with huntingtin: implications for a role in the pathogenesis of Huntington's disease. Hum Mol Genet. 2014;23:4142-60 pubmed publisher
Yu H, Yuan L, Xu M, Zhang Z, Duan H. Sphingosine kinase 1 improves cutaneous wound healing in diabetic rats. Injury. 2014;45:1054-8 pubmed publisher
Martina J, Diab H, Lishu L, Jeong A L, Patange S, Raben N, et al. The nutrient-responsive transcription factor TFE3 promotes autophagy, lysosomal biogenesis, and clearance of cellular debris. Sci Signal. 2014;7:ra9 pubmed publisher
Hwang C, Shiu L, Su L, Yu Fang Yin -, Wang W, Huang S, et al. Oncogenic fibulin-5 promotes nasopharyngeal carcinoma cell metastasis through the FLJ10540/AKT pathway and correlates with poor prognosis. PLoS ONE. 2013;8:e84218 pubmed publisher
Yang C, Swallows C, Zhang C, Lu J, Xiao H, Brady R, et al. Celastrol increases glucocerebrosidase activity in Gaucher disease by modulating molecular chaperones. Proc Natl Acad Sci U S A. 2014;111:249-54 pubmed publisher
Villegas C, Muresan V, Ladescu Muresan Z. Dual-tagged amyloid-? precursor protein reveals distinct transport pathways of its N- and C-terminal fragments. Hum Mol Genet. 2014;23:1631-43 pubmed publisher
Ma B, Zhong L, van Blitterswijk C, Post J, Karperien M. T cell factor 4 is a pro-catabolic and apoptotic factor in human articular chondrocytes by potentiating nuclear factor ?B signaling. J Biol Chem. 2013;288:17552-8 pubmed publisher
Wise J, Berkova Z, Mathur R, Zhu H, Braun F, Tao R, et al. Nucleolin inhibits Fas ligand binding and suppresses Fas-mediated apoptosis in vivo via a surface nucleolin-Fas complex. Blood. 2013;121:4729-39 pubmed publisher
Chang I, Majid S, Saini S, Zaman M, Yamamura S, Chiyomaru T, et al. Hrk mediates 2-methoxyestradiol-induced mitochondrial apoptotic signaling in prostate cancer cells. Mol Cancer Ther. 2013;12:1049-59 pubmed publisher
Ko M, An J, Bandukwala H, Chavez L, Aijö T, Pastor W, et al. Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX. Nature. 2013;497:122-6 pubmed publisher
Noutsios G, Silveyra P, Bhatti F, Floros J. Exon B of human surfactant protein A2 mRNA, alone or within its surrounding sequences, interacts with 14-3-3; role of cis-elements and secondary structure. Am J Physiol Lung Cell Mol Physiol. 2013;304:L722-35 pubmed publisher
Meiler S, Baumer Y, Huang Z, Hoffmann F, Fredericks G, Rose A, et al. Selenoprotein K is required for palmitoylation of CD36 in macrophages: implications in foam cell formation and atherogenesis. J Leukoc Biol. 2013;93:771-80 pubmed publisher
Snider N, Leonard J, Kwan R, Griggs N, Rui L, Omary M. Glucose and SIRT2 reciprocally mediate the regulation of keratin 8 by lysine acetylation. J Cell Biol. 2013;200:241-7 pubmed publisher
Gao F, Ihn H, Medina M, Krauss R. A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function. Hum Mol Genet. 2013;22:1424-31 pubmed publisher
Yang C, Rahimpour S, Lu J, Pacak K, Ikejiri B, Brady R, et al. Histone deacetylase inhibitors increase glucocerebrosidase activity in Gaucher disease by modulation of molecular chaperones. Proc Natl Acad Sci U S A. 2013;110:966-71 pubmed publisher
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Liu X, Yuan J, Wu A, McGonagill P, Galle C, Meier J. Phorbol ester-induced human cytomegalovirus major immediate-early (MIE) enhancer activation through PKC-delta, CREB, and NF-kappaB desilences MIE gene expression in quiescently infected human pluripotent NTera2 cells. J Virol. 2010;84:8495-508 pubmed publisher
Makar A, McMartin K, Palese M, Tephly T. Formate assay in body fluids: application in methanol poisoning. Biochem Med. 1975;13:117-26 pubmed
product information
SKU :
TA50011-100
Category :
Antibodies
Sub-Category :
Tag Antibodies
Name :
Clone OTI4C5, Anti-DDK (FLAG) monoclonal antibody
Description :
Clone OTI4C5, Anti-DDK (FLAG) monoclonal antibody
Size :
100 µl
Price US :
412 USD
Delivery Time US :
In Stock
Symbol :
DDK (FLAG)
Clonality :
Monoclonal
Clone Name :
OTI4C5 (formerly 4C5)
Host :
Mouse
Isotype :
IgG2a
Applications :
FC, IF, IHC, IP, WB
Reactivity :
DDK (FLAG tag): DYKDDDDK
more info or order :
company information
OriGene
9620 Medical Center Dr., Suite 200
Rockville, MD 20850
custsupport@origene.com
https://www.origene.com
1-888-267-4436
headquarters: USA
OriGene Technologies, Inc. is a gene centric life sciences company dedicated to support biomedical scientists in gene functions and drug discovery. OriGene’s novel product line includes the world’s largest collections of cDNA clones (TrueClone and TrueORF), shRNA (HuSH-29), purified human recombinant proteins, high quality TrueMAB™ monoclonal antibodies to human proteins, 100,000 highly validated human tissues, and qPCR arrays. OriGene also provides a broad range of antibody validation products including genome-wide tagged antigen standards and extensive IHC slides derived from our tissue collection. OriGene is a Luminex Certified Partner™ and offers multiplexed immunoassays and multiplexed assays for a broad range of biomarkers.