product summary
Loading...
company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
GPR81 Antibody - BSA Free
catalog :
NLS2095
quantity :
0.05 ml
price :
459 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
RAY
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 12
Reference
Liu W, Zhang S, Li Q, Wu Y, Jia X, Feng W, et al. Lactate modulates iron metabolism by binding soluble adenylyl cyclase. Cell Metab. 2023;35:1597-1612.e6 pubmed publisher
Zhang L, Wang S, Ma Y, Song Y, Li D, Liang X, et al. Shoutai Wan regulates glycolysis imbalance at the maternal-fetal interface in threatened abortion mice. J Ethnopharmacol. 2023;312:116502 pubmed publisher
Okui T, Hiasa M, Hasegawa K, Nakamura T, Ono K, Ibaragi S, et al. Lactate secreted via MCT4 from bone‑colonizing breast cancer excites sensory neurons via GPR81. Int J Oncol. 2023;62: pubmed publisher
Ma R, Li X, Gong S, Ge X, Zhu T, Ge X, et al. Dual Roles of Lactate in EGFR-TKI-Resistant Lung Cancer by Targeting GPR81 and MCT1. J Oncol. 2022;2022:3425841 pubmed publisher
Ishihara S, Hata K, Hirose K, Okui T, Toyosawa S, Uzawa N, et al. The lactate sensor GPR81 regulates glycolysis and tumor growth of breast cancer. Sci Rep. 2022;12:6261 pubmed publisher
Murakami R, Chiba Y, Nishi N, Matsumoto K, Wakamatsu K, Yanase K, et al. Immunoreactivity of receptor and transporters for lactate located in astrocytes and epithelial cells of choroid plexus of human brain. Neurosci Lett. 2021;741:135479 pubmed publisher
Brown T, Bhattacharjee P, Ramachandran S, Sivaprakasam S, Ristic B, Sikder M, et al. The lactate receptor GPR81 promotes breast cancer growth via a paracrine mechanism involving antigen-presenting cells in the tumor microenvironment. Oncogene. 2020;39:3292-3304 pubmed publisher
de Castro Abrantes H, Briquet M, Schmuziger C, Restivo L, Puyal J, Rosenberg N, et al. The Lactate Receptor HCAR1 Modulates Neuronal Network Activity through the Activation of Gα and Gβγ Subunits. J Neurosci. 2019;39:4422-4433 pubmed publisher
Vanderperre B, Lucier J, Bissonnette C, Motard J, Tremblay G, Vanderperre S, et al. Direct detection of alternative open reading frames translation products in human significantly expands the proteome. PLoS ONE. 2013;8:e70698 pubmed publisher
Kluk B, Fu Y, Formolo T, Zhang L, Hindle A, Man Y, et al. BP1, an isoform of DLX4 homeoprotein, negatively regulates BRCA1 in sporadic breast cancer. Int J Biol Sci. 2010;6:513-24 pubmed
Yin J, Wei Z, Li K, Cao Y, Guo W. Identification and molecular characterization of a new member of the peritrophic membrane proteins from the meadow moth, loxostege sticticalis. Int J Biol Sci. 2010;6:491-8 pubmed
Okada S, Ouchi T. Cell cycle differences in DNA damage-induced BRCA1 phosphorylation affect its subcellular localization. J Biol Chem. 2003;278:2015-20 pubmed
product information
master code :
NLS2095
SKU :
NLS2095
product name :
GPR81 Antibody - BSA Free
unit size :
0.05 ml
description :
The GPR81 Antibody - BSA Free from Novus is a rabbit polyclonal antibody to GPR81. This antibody reacts with human,mouse,rat. The GPR81 Antibody - BSA Free has been validated for the following applications: Western Blot,IF/IHC,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry.
target :
GPR81
category :
Primary Antibodies
buffer :
PBS
clonality :
Polyclonal
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
Synthetic 19 amino acid peptide from C-terminus of human GPR81.
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human,Mouse,Rat
specificity :
Human GPR81
gene symbol :
HCAR1
accessionNumbers :
Q9BXC0
applications :
IF/IHC,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry
USD :
459 USD
alt names :
FKSG80, G protein-coupled receptor 104, G protein-coupled receptor 81, GPR104, G-protein coupled receptor 104, G-protein coupled receptor 81, HCA1, HCAR1, LACR1, lactate receptor 1, TA-GPCR, T-cell activation G protein-coupled receptor
storage :
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.