NLRP3/NALP3 Antibody (SC06-23) | Novus Biologicals NBP2-67639 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

NLRP3/NALP3 Antibody (SC06-23)

catalog :

NBP2-67639

quantity :

100 ul

price :

479 USD

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

SC06-23

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section

more info or order :

Novus Biologicals product webpage

citations: 9

Reference
Fu Y, Cao J, Wei X, Ge Y, Su Z, Yu D. Klotho alleviates contrast-induced acute kidney injury by suppressing oxidative stress, inflammation, and NF-KappaB/NLRP3-mediated pyroptosis. Int Immunopharmacol. 2023;118:110105 pubmed publisher
Lee S, Ryu S, Kim D, Lee Y, Lee S, Kang S, et al. Neuroprotective effect of Geijigadaehwang-tang against trimethyltin-induced hippocampal neurodegeneration: An in vitro and in vivo study. J Ethnopharmacol. 2022;296:115451 pubmed publisher
Abu Risha S, Mousa M, Elsisi A. Protective role of irbesartan against cyclophosphamide-induced testicular damage in rats via up-regulating PPAR-γ signaling and ameliorating NF-κB/NLRP3/IL-18 inflammatory axis. Life Sci. 2022;289:120218 pubmed publisher
Kanzaki G, Nagasaka S, Higo S, Kajimoto Y, Kanemitsu T, Aoki M, et al. Impact of anti-glomerular basement membrane antibodies and glomerular neutrophil activation on glomerulonephritis in experimental myeloperoxidase-antineutrophil cytoplasmic antibody vasculitis. Nephrol Dial Transplant. 2016;31:574-85 pubmed publisher
Nahrendorf M, Sosnovik D, Chen J, Panizzi P, Figueiredo J, Aikawa E, et al. Activatable magnetic resonance imaging agent reports myeloperoxidase activity in healing infarcts and noninvasively detects the antiinflammatory effects of atorvastatin on ischemia-reperfusion injury. Circulation. 2008;117:1153-60 pubmed publisher
Matthijsen R, Huugen D, Hoebers N, de Vries B, Peutz Kootstra C, Aratani Y, et al. Myeloperoxidase is critically involved in the induction of organ damage after renal ischemia reperfusion. Am J Pathol. 2007;171:1743-52 pubmed
van Leeuwen M, Gijbels M, Duijvestijn A, Smook M, van de Gaar M, Heeringa P, et al. Accumulation of myeloperoxidase-positive neutrophils in atherosclerotic lesions in LDLR-/- mice. Arterioscler Thromb Vasc Biol. 2008;28:84-9 pubmed
Wang D, D Costa J, Civin C, Friedman A. C/EBPalpha directs monocytic commitment of primary myeloid progenitors. Blood. 2006;108:1223-9 pubmed
Huugen D, Xiao H, van Esch A, Falk R, Peutz Kootstra C, Buurman W, et al. Aggravation of anti-myeloperoxidase antibody-induced glomerulonephritis by bacterial lipopolysaccharide: role of tumor necrosis factor-alpha. Am J Pathol. 2005;167:47-58 pubmed

product information

master code :

NBP2-67639

SKU :

NBP2-67639

product name :

NLRP3/NALP3 Antibody (SC06-23)

unit size :

100 ul

description :

The NLRP3/NALP3 Antibody (SC06-23) from Novus is a rabbit monoclonal antibody to NLRP3/NALP3. This antibody reacts with human,mouse,rat. The NLRP3/NALP3 Antibody (SC06-23) has been validated for the following applications: IF/IHC,Western Blot,Flow Cytometry,Immunohistochemistry,Immunoprecipitation,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence.

target :

NLRP3/NALP3

category :

Primary Antibodies

buffer :

TBS (pH7.4), 0.05% BSA, 40% Glycerol

clonality :

Monoclonal

clone :

SC06-23

concentration :

1 mg/ml

conjugate :

Unconjugated

host :

Rabbit

immunogen :

Recombinant protein within Human NLRP3/NALP3 aa 5-161/ 1036. (SwissProt: Q96P20 Human; SwissProt: Q8R4B8 Mouse; Entrez Gene: 287362 Rat)

isotype :

IgG

purity :

Protein A purified

species :

Human,Mouse,Rat

theoretical molecular weight :

118 kDa

gene symbol :

NLRP3

applications :

IF/IHC,Western Blot,Flow Cytometry,Immunohistochemistry,Immunoprecipitation,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence

extended description :

Recombinant Monoclonal Antibody.

USD :

479 USD

product details :

Recombinant Monoclonal Antibody.

alt names :

AII, AII/AVP, Angiotensin/vasopressin receptor AII/AVP-like, AVP, C1orf7, Caterpiller protein 1.1, CLR1.1, Cold autoinflammatory syndrome 1, Cold autoinflammatory syndrome 1 protein, Cryopyrin, Familial cold autoinflammatory syndrome, FCU, Leucine-rich repeat-, and PYD-containing protein 3, Muckle-Wells syndrome, MWS, NACHT, LRR and PYD containing protein 3, NACHT, LRR and PYD domains-containing protein 3, NALP3, NLR family, pyrin domain containing 3, NLRP3, Nucleotide-Binding Oligomerization Domain, Leucine Rich Repeat And Pyrin Domain Containing 3, PYPAF1, PYRIN-containing APAF1-like protein 1

storage :

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage