product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
FANCD2 Antibody (1290D) - BSA Free
catalog :
NBP2-54808
quantity :
0.1 mg (also 0.025 mg)
price :
409 USD
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
1290D
reactivity :
human
application :
western blot, immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 12
Reference
Sridharan S, Robeson M, Bastihalli Tukaramrao D, Howard C, Subramaniyan B, Tilley A, et al. Targeting of the Eukaryotic Translation Initiation Factor 4A Against Breast Cancer Stemness. Front Oncol. 2019;9:1311 pubmed publisher
Zhang S, Chatterjee T, Godoy C, Wu L, Liu Q, Carmon K. GPR56 Drives Colorectal Tumor Growth and Promotes Drug Resistance through Upregulation of MDR1 Expression via a RhoA-Mediated Mechanism. Mol Cancer Res. 2019;17:2196-2207 pubmed publisher
Li K, Ouyang L, He M, Luo M, Cai W, Tu Y, et al. IDH1 R132H mutation regulates glioma chemosensitivity through Nrf2 pathway. Oncotarget. 2017;8:28865-28879 pubmed publisher
Koshkin V, Ailles L, Liu G, Krylov S. Metabolic Suppression of a Drug-Resistant Subpopulation in Cancer Spheroid Cells. J Cell Biochem. 2016;117:59-65 pubmed publisher
Grybauskas A, Koga T, Kuprys P, Nolan M, McCarty R, Walker L, et al. ABCB1 transporter and Toll-like receptor 4 in trabecular meshwork cells. Mol Vis. 2015;21:201-12 pubmed
Kurihara Y, Sawazumi T, Takeuchi T. Exploration of interactions between membrane proteins embedded in supported lipid bilayers and their antibodies by reflectometric interference spectroscopy-based sensing. Analyst. 2014;139:6016-21 pubmed publisher
Chen Y, Lukka P, Joseph W, Finlay G, Paxton J, McKeage M, et al. Selective cellular uptake and retention of SN 28049, a new DNA-binding topoisomerase II-directed antitumor agent. Cancer Chemother Pharmacol. 2014;74:25-35 pubmed publisher
Tiwari A, Zhang R, Gallo J. Overlapping functions of ABC transporters in topotecan disposition as determined in gene knockout mouse models. Mol Cancer Ther. 2013;12:1343-55 pubmed publisher
Chen Q, Yang Y, Li L, Zhang J. The amino terminus of the human multidrug resistance transporter ABCC1 has a U-shaped folding with a gating function. J Biol Chem. 2006;281:31152-63 pubmed
Binyamin L, Assaraf Y, Reiter Y. Probing ATP-dependent conformational changes in the multidrug resistance protein 1 (MRP1/ABCC1) in live tumor cells with a novel recombinant single-chain Fv antibody targeted to the extracellular N-terminus. Int J Cancer. 2005;116:703-9 pubmed
Yang Y, Chen Q, Zhang J. Structural and functional consequences of mutating cysteine residues in the amino terminus of human multidrug resistance-associated protein 1. J Biol Chem. 2002;277:44268-77 pubmed
Chen Q, Yang Y, Liu Y, Han B, Zhang J. Cytoplasmic retraction of the amino terminus of human multidrug resistance protein 1. Biochemistry. 2002;41:9052-62 pubmed
product information
master code :
NBP2-54808
SKU :
NBP2-54808
product name :
FANCD2 Antibody (1290D) - BSA Free
unit size :
0.1 mg (also 0.025 mg)
description :
The FANCD2 Antibody (1290D) - BSA Free from Novus is a rabbit monoclonal antibody to FANCD2. This antibody reacts with human. The FANCD2 Antibody (1290D) - BSA Free has been validated for the following applications: Flow Cytometry,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Flow (Intracellular),Simple Western,Knockout Validated.
target :
FANCD2
category :
Primary Antibodies
buffer :
PBS
clonality :
Monoclonal
clone :
1290D
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
This FANCD2 Antibody (1290D) was developed against human FANCD2 fusion protein (N-terminal fragment). [Swiss-Prot #Q9BXW9]
isotype :
IgG
purity :
Protein A or G purified from cell culture supernatant
species :
Human
theoretical molecular weight :
164.1 kDa
gene symbol :
FANCD2
Antibody validation :
Knockout/Knockdown
applications :
Flow Cytometry,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Flow (Intracellular),Simple Western,Knockout Validated
extended description :
Recombinant Monoclonal Antibody.
USD :
409 USD
product details :
Recombinant Monoclonal Antibody.
alt names :
DKFZp762A223, FA4, FACD, FAD, FAD2, FA-D2, FADFAD2, FANCD, Fanconi anemia complementation group D2, Fanconi anemia group D2 protein, Fanconi anemia, complementation group D2, FLJ23826, FPN1, HFE4, IREG1, Protein FACD2, SLC11A3
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.