product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
FANCM Antibody (CV5.1) - BSA Free
catalog :
NBP2-50418
quantity :
0.1 ml (also 0.025 ml)
price :
349 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
CV5.1
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
citations: 9
Reference
Feng S, Liu K, Shang J, Hoeg L, Pastore G, Yang W, et al. Profound synthetic lethality between SMARCAL1 and FANCM. Mol Cell. 2024;84:4522-4537.e7 pubmed publisher
Lu R, Nelson C, Rogers S, Cesare A, Sobinoff A, Pickett H. Distinct modes of telomere synthesis and extension contribute to Alternative Lengthening of Telomeres. iScience. 2024;27:108655 pubmed publisher
Dzaparidze G, Kazachonok D, Gvozdkov A, Taelma H, Laht K, Minajeva A. Diagnostic significance of stromal changes in biopsies of prostate adenocarcinoma. Pathol Res Pract. 2021;222:153436 pubmed publisher
Brannvoll A, Xue X, Kwon Y, Kompocholi S, Simonsen A, Viswalingam K, et al. The ZGRF1 Helicase Promotes Recombinational Repair of Replication-Blocking DNA Damage in Human Cells. Cell Rep. 2020;32:107849 pubmed publisher
Dzaparidze G, Anion E, Laan M, Minajeva A. The decline of FANCM immunohistochemical expression in prostate cancer stroma correlates with the grade group. Pathol Int. 2020;70:542-550 pubmed publisher
Lu R, O Rourke J, Sobinoff A, Allen J, Nelson C, Tomlinson C, et al. The FANCM-BLM-TOP3A-RMI complex suppresses alternative lengthening of telomeres (ALT). Nat Commun. 2019;10:2252 pubmed publisher
James N, Cantillo E, Yano N, Chichester C, DiSilvestro P, Hovanesian V, et al. Septin-2 is overexpressed in epithelial ovarian cancer and mediates proliferation via regulation of cellular metabolic proteins. Oncotarget. 2019;10:2959-2972 pubmed publisher
Kasak L, Punab M, Nagirnaja L, Grigorova M, Minajeva A, Lopes A, et al. Bi-allelic Recessive Loss-of-Function Variants in FANCM Cause Non-obstructive Azoospermia. Am J Hum Genet. 2018;103:200-212 pubmed publisher
Fouquet B, Pawlikowska P, Caburet S, Guigon C, Mäkinen M, Tanner L, et al. A homozygous FANCM mutation underlies a familial case of non-syndromic primary ovarian insufficiency. elife. 2017;6: pubmed publisher
product information
master code :
NBP2-50418
SKU :
NBP2-50418
product name :
FANCM Antibody (CV5.1) - BSA Free
unit size :
0.1 ml (also 0.025 ml)
description :
The FANCM Antibody (CV5.1) - BSA Free from Novus is a mouse monoclonal antibody to FANCM. This antibody reacts with human. The FANCM Antibody (CV5.1) - BSA Free has been validated for the following applications: Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry,Immunoprecipitation,Knockdown Validated,Immunocytochemistry/ Immunofluorescence.
target :
FANCM
category :
Primary Antibodies
buffer :
PBS
clonality :
Monoclonal
clone :
CV5.1
concentration :
1 mg/ml
conjugate :
Unconjugated
host :
Mouse
immunogen :
His-tagged denatured FANCM (aa 1507-1679) made in E.coli
isotype :
IgG1 Kappa
purity :
Protein A purified
species :
Human
gene symbol :
FANCM
Antibody validation :
Knockout/Knockdown
applications :
Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry,Immunoprecipitation,Knockdown Validated,Immunocytochemistry/ Immunofluorescence
USD :
349 USD
alt names :
ATP-dependent RNA helicase FANCM, EC 3.6.1, FAAP250EC 3.6.4.13, Fanconi anemia, complementation group M, Fanconi anemia-associated polypeptide of 250 kDa, KIAA1596Fanconi anemia group M protein, MGC176453, Protein FACM, Protein Hef ortholog
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.