product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
SMPD1 Antibody (OTI3H7)
catalog :
NBP2-45889
quantity :
0.1 ml
price :
479 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
OTI3H7
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 6
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - frozen section; human; 1:150; loading ...; fig 3
Boer D, Van Smeden J, Al Khakany H, Melnik E, van Dijk R, Absalah S, et al. Skin of atopic dermatitis patients shows disturbed β-glucocerebrosidase and acid sphingomyelinase activity that relates to changes in stratum corneum lipid composition. Biochim Biophys Acta Mol Cell Biol Lipids. 2020;1865:158673 pubmed publisher
Van Smeden J, Al Khakany H, Wang Y, Visscher D, Stephens N, Absalah S, et al. Skin barrier lipid enzyme activity in Netherton patients is associated with protease activity and ceramide abnormalities. J Lipid Res. 2020;61:859-869 pubmed publisher
Rana S, Espinosa Díez C, Ruhl R, Chatterjee N, Hudson C, Fraile Bethencourt E, et al. Differential regulation of microRNA-15a by radiation affects angiogenesis and tumor growth via modulation of acid sphingomyelinase. Sci Rep. 2020;10:5581 pubmed publisher
Hayashi K, Nakazato Y, Morito N, Sagi M, Fujita T, Anzai N, et al. Fluvastatin is effective against thymic carcinoma. Life Sci. 2020;240:117110 pubmed publisher
Scharinger B, Messner B, Türkcan A, Schuster D, Vuorinen A, Pitterl F, et al. Leoligin, the major lignan from Edelweiss, inhibits 3-hydroxy-3-methyl-glutaryl-CoA reductase and reduces cholesterol levels in ApoE-/- mice. J Mol Cell Cardiol. 2016;99:35-46 pubmed publisher
Gustbée E, Tryggvadottir H, Markkula A, Simonsson M, Nodin B, Jirström K, et al. Tumor-specific expression of HMG-CoA reductase in a population-based cohort of breast cancer patients. BMC Clin Pathol. 2015;15:8 pubmed publisher
product information
master code :
NBP2-45889
SKU :
NBP2-45889
product name :
SMPD1 Antibody (OTI3H7)
unit size :
0.1 ml
description :
The SMPD1 Antibody (OTI3H7) from Novus is a mouse monoclonal antibody to SMPD1. This antibody reacts with human,mouse. The SMPD1 Antibody (OTI3H7) has been validated for the following applications: Flow Cytometry,Western Blot,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Immunohistochemistry-Paraffin.
target :
SMPD1
category :
Primary Antibodies
buffer :
PBS (pH 7.3), 1.0% BSA and 50% Glycerol
clonality :
Monoclonal
clone :
OTI3H7
concentration :
1 mg/ml
conjugate :
Unconjugated
host :
Mouse
immunogen :
Human recombinant protein fragment corresponding to amino acids 62-341 of human SMPD1 (NP_000534) produced in E.coli.
isotype :
IgG1
purity :
Immunogen affinity purified
species :
Human,Mouse
gene symbol :
SMPD1
applications :
Flow Cytometry,Western Blot,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Immunohistochemistry-Paraffin
USD :
479 USD
alt names :
Acid sphingomyelinase, ASMASE, ASMsphingomyelin phosphodiesterase, EC 3.1.4.12, NPD, sphingomyelin phosphodiesterase 1, acid lysosomal
storage :
Store at -20C. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.