HLA A Antibody (108-2C5) | Novus Biologicals NBP2-45320-0.1mg product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

HLA A Antibody (108-2C5)

catalog :

NBP2-45320-0.1mg

quantity :

0.1 mg (also 0.02 mg)

price :

349 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

108-2C5

reactivity :

human

application :

immunocytochemistry, flow cytometry

product information

brand :

Novus

master code :

NBP2-45320

SKU :

NBP2-45320-0.1mg

product name :

HLA A Antibody (108-2C5)

description :

The HLA A Antibody (108-2C5) from Novus Biologicals is a mouse monoclonal antibody to HLA A. This antibody reacts with human. The HLA A Antibody (108-2C5) has been validated for the following applications: Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunofluorescence.

target :

HLA A

category :

Primary Antibodies

unit size :

0.1 mg (also 0.02 mg)

buffer :

10 mM PBS with 0.05% BSA

clonality :

Monoclonal

clone :

108-2C5

concentration :

0.2 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

Normal human peripheral blood lymphocytes

isotype :

IgG1 Kappa

purity :

Bioreactor concentrate

species :

Human

specificity :

HLA-A, with HLA-B and HLA-C, belongs to major histocompatibility complex (MHC) class I antigens and expresses constitutively on all nucleated cells. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation. This MAb is useful for HLA molecular typing of peripheral blood leukocytes as well as a large number of leukemic cell lines. It reacts with an intralocus determinant present on a limited number of HLA-A locus-encoded gene products (HLA-A2, -A3, -A28, -A29, -A30, -A31 and Aw33). Its epitope maps between aa65-to-aa80 of the ?1 domain of the HLA-A. This MAb recognizes an intralocus determinant present on a limited number of HLA-A locus-encoded gene products (HLA-A2, -A3, A28, -A29, -A30, -A31 and -Aw33). Furthermore, by testing its reactivity with HLA-A2 natural variants and mutants, the importance of amino acid residues 79 and/or 80 of the alpha 1 domain was demonstrated in the formation of an intralocus HLA-A determinant.

theoretical molecular weight :

41 kDa

gene symbol :

HLA-A

catalog number base :

NBP2-45320

applications :

Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunofluorescence

USD 2021 :

349

USD 2022 :

349 USD

atl names :

A-10 alpha chain, FLJ26655, HLA class I histocompatibility antigen, A-1 alpha chain, HLA class I histocompatibility antigen, A-28 alpha chain, HLA class I histocompatibility antigen, A-9 alpha chain, HLAA, major histocompatibility complex, class I, A, MHC class I antigen A*1, MHC class I antigen A*11, MHC class I antigen A*80

storage :

Store at 4C.