CD55 / DAF Antibody (143-30) | Novus Biologicals NBP2-44873 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

CD55 / DAF Antibody (143-30)

catalog :

NBP2-44873

quantity :

0.1 mg (also 0.02 mg)

price :

329 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

143-30

reactivity :

human

application :

immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - frozen section

citations: 1

Reference
Garrison C, Lastwika K, Zhang Y, Li C, Lampe P. Proteomic Analysis, Immune Dysregulation, and Pathway Interconnections with Obesity. J Proteome Res. 2017;16:274-287 pubmed publisher

product information

brand :

Novus

master code :

NBP2-44873

SKU :

NBP2-44873-0.1mg

product name :

CD55 / DAF Antibody (143-30)

description :

The CD55/DAF Antibody (143-30) from Novus is a mouse monoclonal antibody to CD55/DAF. This antibody reacts with human. The CD55/DAF Antibody (143-30) has been validated for the following applications: Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen, Flow (Cell Surface).

target :

CD55 / DAF

category :

Primary Antibodies

unit size :

0.1 mg (also 0.02 mg)

buffer :

10 mM PBS with 0.05% BSA

clonality :

Monoclonal

clone :

143-30

concentration :

0.2 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

PHA stimulated human PBL

isotype :

IgG1 Kappa

purity :

Protein A or G purified

species :

Human

specificity :

Recognizes a single chain glycoprotein of 70kDa, identified as CD55 (also known as decay accelerating factor, DAF). CD55/DAF is widely expressed on cells throughout the body including leukocytes, erythrocytes, epithelium, endothelium, and fibroblasts. It is a Glycosyl phosphatidylinositol anchored (GPI-anchored) member of the membrane bound complement regulatory proteins that inhibit autologous complement cascade activation. It prevents the amplification steps of the complement cascade by interfering with the assembly of the C3-convertases, C4b2a and C3bBb, and the C5-convertase, C4b2a3b and C3bBb3b. CD55 also serves as receptor for CD97 and for echovirus and Coxsackie B virus. The MAb 143-30 can be used as marker for paroxysmal nocturnal hemoglobinuria (PNH).

theoretical molecular weight :

70 kDa

gene symbol :

CD55

catalog number base :

NBP2-44873

accessionNumbers :

P08174, P08174

applications :

Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen, Flow (Cell Surface)

USD :

329 USD

alt names :

CD55 antigen, CD55 molecule, decay accelerating factor for complement (Cromer blood group), CRdecay accelerating factor for complement (CD55, Cromer blood group system), CROMDAFcomplement decay-accelerating factor, decay accelerating factor for complement, TC

storage :

Store at 4C.