CD43 / Sialophorin Antibody (SPN / 839) - Azide and BSA Free | Novus Biologicals NBP2-44648 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

CD43 / Sialophorin Antibody (SPN / 839) - Azide and BSA Free

catalog :

NBP2-44648

quantity :

0.1 mg

price :

329 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

SPN/839

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

citations: 2

Reference
Li J, Zeng C, Zheng B, Liu C, Tang M, Jiang Y, et al. HMGB1-induced autophagy facilitates hepatic stellate cells activation: a new pathway in liver fibrosis. Clin Sci (Lond). 2018;132:1645-1667 pubmed publisher
Attard G, Crespo M, Lim A, Pope L, Zivi A, de Bono J. Reporting the capture efficiency of a filter-based microdevice: a CTC is not a CTC unless it is CD45 negative--letter. Clin Cancer Res. 2011;17:3048-9; author reply 3050 pubmed publisher

product information

brand :

Novus

master code :

NBP2-44648

SKU :

NBP2-47879-0.1mg

product name :

CD43 / Sialophorin Antibody (SPN / 839) - Azide and BSA Free

description :

The CD43/Sialophorin Antibody (SPN/839) - Azide and BSA Free from Novus is a mouse monoclonal antibody to CD43/Sialophorin. This antibody reacts with human. The CD43/Sialophorin Antibody (SPN/839) - Azide and BSA Free has been validated for the following applications: Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunofluorescence, CyTOF-ready.

target :

CD43 / Sialophorin

category :

Primary Antibodies

unit size :

0.1 mg

buffer :

10 mM PBS

clonality :

Monoclonal

clone :

SPN/839

concentration :

1.0 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

Recombinant full-length human SPN protein

isotype :

IgG1 Kappa

purity :

Protein A or G purified

species :

Human

specificity :

It recognizes a cell surface glycoprotein of 95/115/135kDa (depending upon the extent of glycosylation), identified as CD43. 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma.

gene symbol :

SPN

catalog number base :

NBP2-47879

applications :

Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunofluorescence, CyTOF-ready

USD :

329 USD

alt names :

CD43 antigen, CD43), Galactoglycoprotein, GALGP, Leukocyte sialoglycoprotein, Sialophorin, sialophorin (gpL115, leukosialin, CD43)

storage :

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.