CD11c Antibody (ITGAX/1243) | Novus Biologicals NBP2-44599 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

CD11c Antibody (ITGAX/1243)

catalog :

NBP2-44599

quantity :

0.02 mg

price :

149 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

ITGAX/1243

reactivity :

human

application :

immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

citations: 1

Reference
Offenbacher S, Jiao Y, Kim S, Marchesan J, Moss K, Jing L, et al. GWAS for Interleukin-1β levels in gingival crevicular fluid identifies IL37 variants in periodontal inflammation. Nat Commun. 2018;9:3686 pubmed publisher

product information

brand :

Novus

master code :

NBP2-44599

SKU :

NBP2-44599-0.02mg

product name :

CD11c Antibody (ITGAX/1243)

description :

The CD11c Antibody (ITGAX/1243) from Novus Biologicals is a mouse monoclonal antibody to CD11c. This antibody reacts with human. The CD11c Antibody (ITGAX/1243) has been validated for the following applications: Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Protein Array, Immunofluorescence.

target :

CD11c

category :

Primary Antibodies

unit size :

0.02 mg

buffer :

10 mM PBS with 0.05% BSA

clonality :

Monoclonal

clone :

ITGAX/1243

concentration :

0.2 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

Recombinant fragment (191 Amino acid residues between aa 600-850) of human ITGAX protein

isotype :

IgG2b Kappa

purity :

Protein A or G purified

species :

Human

specificity :

Recognizes a protein of 145kDa, identified as CD11c. CD11c (ITGAX), a member of the leukointegrin family, shares the same beta subunit with other members of the leukocyte adhesion molecule family, which includes CD11a (LFA-1), CD11b (MAC-1) and CD11d (ITGAD), but has a unique alpha chain. CD11c has been shown to play a role in phagocytosis, cell migration, and cytokine production by monocytes/macrophages as well as induction of T-cell proliferation by Langerhans cells. CD11c is expressed prominently on the plasma membranes of monocytes, tissue macrophages, NK cells, and most dendritic cells (DCs). A lower level of expression is also observed on neutrophils as a result of its high level of expression on most DCs. An antibody to CD11c may aid in identification of lesions with histiocytic origin. It may also been used as a marker for hairy cell leukemia in paraffin-embedded tissues

theoretical molecular weight :

145 kDa

gene symbol :

ITGAX

catalog number base :

NBP2-44599

applications :

Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Protein Array, Immunofluorescence

2020 USD :

129

2021 USD :

149 USD

alt names :

95, 95 alpha chain, 95, alpha subunit, CD11 antigen-like family member C, CD11c, CD11c antigen, CD11Cleu M5, alpha subunit, integrin alpha-X, integrin, alpha X (antigen CD11C (p150), alpha polypeptide), integrin, alpha X (complement component 3 receptor 4 subunit), Leu M5, Leukocyte adhesion glycoprotein p150, Leukocyte adhesion receptor p150, leukocyte surface antigen p150, myeloid membrane antigen, alpha subunit, p150 95 integrin alpha chain, SLEB6

storage :

Store at 4C.