p21/CIP1/CDKN1A Antibody (DCS-60.2) | Novus Biologicals NBP2-44525 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

p21/CIP1/CDKN1A Antibody (DCS-60.2)

catalog :

NBP2-44525

quantity :

0.02 mg

price :

149 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

DCS-60.2

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

citations: 2

Reference
Tordjman J, Majumder M, Amiri M, Hasan A, Hess D, Lala P. Tumor suppressor role of cytoplasmic polyadenylation element binding protein 2 (CPEB2) in human mammary epithelial cells. BMC Cancer. 2019;19:561 pubmed publisher
Ponandai Srinivasan S, Lalitkumar P, Garcia L, Varghese S, Carlson J, Gemzell Danielsson K, et al. Mifepristone mediates anti-proliferative effect on ovarian mesenchymal stem/stromal cells from female BRCA1-/2- carriers. Acta Obstet Gynecol Scand. 2019;98:250-261 pubmed publisher

product information

brand :

Novus

master code :

NBP2-44525

SKU :

NBP2-44525-0.02mg

product name :

p21/CIP1/CDKN1A Antibody (DCS-60.2)

description :

The p21/CIP1/CDKN1A Antibody (DCS-60.2) from Novus Biologicals is a mouse monoclonal antibody to p21/CIP1/CDKN1A. This antibody reacts with human, mouse (negative), rat (negative). The p21/CIP1/CDKN1A Antibody (DCS-60.2) has been validated for the following applications: Western Blot, Simple Western, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence.

target :

p21/CIP1/CDKN1A

category :

Primary Antibodies

unit size :

0.02 mg

buffer :

10 mM PBS with 0.05% BSA

clonality :

Monoclonal

clone :

DCS-60.2

concentration :

0.2 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

Human recombinant p21 protein

isotype :

IgG2a Kappa

purity :

Protein A or G purified

species :

Human, Mouse (Negative), Rat (Negative)

specificity :

This MAb recognizes a 21kDa protein, identified as the p21WAF1 tumor suppressor protein. This MAb is highly specific to p21 and shows no cross-reaction with other closely related mitotic inhibitors. p21WAF1 is a specific inhibitor of cdk s and a tumor suppressor involved in the pathogenesis of a variety of malignancies. The expression of this gene acts as an inhibitor of the cell cycle during G1 phase and is tightly controlled by the tumor suppressor protein p53. Its expression is induced by the wild type, but not mutant, p53 suppressor protein. Normal cells generally display a rather intense nuclear p21 expression. Loss of p21 expression has been reported in many carcinomas (gastric carcinoma, non-small cell lung carcinoma, thyroid carcinoma).

theoretical molecular weight :

21 kDa

gene symbol :

CDKN1A

catalog number base :

NBP2-44525

accessionNumbers :

P38936, P38936

applications :

Western Blot, Simple Western, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence

2020 USD :

129

2021 USD :

149 USD

alt names :

CAP20cyclin-dependent kinase inhibitor 1, CDK-interacting protein 1, CDKN1melanoma differentiation associated protein 6, CIP1WAF1CDK-interaction protein 1, cyclin-dependent kinase inhibitor 1A (p21, Cip1), MDA6, MDA-6, Melanoma differentiation-associated protein 6, p21, p21CIP1, p21Cip1/Waf1, PIC1, SDI1DNA synthesis inhibitor, wild-type p53-activated fragment 1

storage :

Store at 4C.