PMEL17/SILV Antibody (HMB45) | Novus Biologicals NBP2-44520-0.1mg product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

PMEL17/SILV Antibody (HMB45)

catalog :

NBP2-44520-0.1mg

quantity :

0.1 mg (also 0.02 mg)

price :

429 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

HMB45

reactivity :

human, rat, dogs

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

more info or order :

Novus Biologicals product webpage

citations: 7

Reference
Hodges E, Chrystal P, Footz T, Doucette L, Noel N, Li Z, et al. Disrupting the Repeat Domain of Premelanosome Protein (PMEL) Produces Dysamyloidosis and Dystrophic Ocular Pigment Reflective of Pigmentary Glaucoma. Int J Mol Sci. 2023;24: pubmed publisher
Kruczek K, Qu Z, Welby E, Shimada H, Hiriyanna S, English M, et al. In vitro modeling and rescue of ciliopathy associated with IQCB1/NPHP5 mutations using patient-derived cells. Stem Cell Reports. 2022;17:2172-2186 pubmed publisher
Hernandez J, Wang X, Vazquez Segoviano M, Lopez Marfil M, Sobral Reyes M, Moran Horowich A, et al. A tissue-bioengineering strategy for modeling rare human kidney diseases in vivo. Nat Commun. 2021;12:6496 pubmed publisher
Afanasyeva T, Corral Serrano J, Garanto A, Roepman R, Cheetham M, Collin R. A look into retinal organoids: methods, analytical techniques, and applications. Cell Mol Life Sci. 2021;78:6505-6532 pubmed publisher
Phelan M, Kruczek K, Wilson J, Brooks M, Drinnan C, Regent F, et al. Soy Protein Nanofiber Scaffolds for Uniform Maturation of Human Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium. Tissue Eng Part C Methods. 2020;26:433-446 pubmed publisher
Helmink B, Reddy S, Gao J, Zhang S, Basar R, Thakur R, et al. B cells and tertiary lymphoid structures promote immunotherapy response. Nature. 2020;577:549-555 pubmed publisher
Lahola Chomiak A, Footz T, Nguyen Phuoc K, Neil G, Fan B, Allen K, et al. Non-Synonymous variants in premelanosome protein (PMEL) cause ocular pigment dispersion and pigmentary glaucoma. Hum Mol Genet. 2019;28:1298-1311 pubmed publisher

product information

master code :

NBP2-44520

SKU :

NBP2-44520-0.1mg

product name :

PMEL17/SILV Antibody (HMB45)

unit size :

0.1 mg (also 0.02 mg)

description :

The PMEL17/SILV Antibody (HMB45) from Novus is a mouse monoclonal antibody to PMEL17/SILV. This antibody reacts with canine (negative),human,rat (negative). The PMEL17/SILV Antibody (HMB45) has been validated for the following applications: Western Blot,Flow Cytometry,Multiplex Immunoassay,Immunohistochemistry,Immunohistochemistry-Paraffin,Flow (Intracellular),Immunofluorescence,Immunocytochemistry/ Immunofluorescence.

target :

PMEL17/SILV

category :

Primary Antibodies

buffer :

10 mM PBS with 0.05% BSA

clonality :

Monoclonal

clone :

HMB45

concentration :

0.2 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

Extract of pigmented melanoma metastases from lymph nodes

isotype :

IgG1 Kappa

purity :

Protein A or G purified

species :

Canine (Negative),Human,Rat (Negative)

specificity :

The gp100 molecule is a 100kDa glycosylated protein that is cleaved into a small (26kDa) carboxy-terminal fragment and a larger amino- terminal section (6038kDa fragments

gene symbol :

PMEL

accessionNumbers :

P40967

applications :

Flow Cytometry,Western Blot,Multiplex Immunoassay,Immunohistochemistry,Immunohistochemistry-Paraffin,Flow (Intracellular),Immunofluorescence,Immunocytochemistry/ Immunofluorescence

USD :

429 USD

alt names :

D12S53EP1, gp100, ME20, ME20-M, melanocyte protein mel 17, Melanocyte protein Pmel 17, Melanocytes lineage-specific antigen GP100, Melanoma-associated ME20 antigen, melanosomal matrix protein17, PMEL17P100, premelanosome proteinME20M, SI, SIL, silver (mouse homolog) like, silver homolog (mouse), Silver locus protein homolog, silver, mouse, homolog of, SILVPmel17

storage :

Store at 4C.

more info or order :

Novus Biologicals product webpage