This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
MCAM/CD146 Antibody (MUC18/1130)
catalog :
NBP2-44512
quantity :
0.02 mg
price :
149 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
MUC18/1130
reactivity :
human
application :
immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
citations: 2
Reference
Roy A, Ghosh A, Kumar B, Chandran B. IFI16, a nuclear innate immune DNA sensor, mediates epigenetic silencing of herpesvirus genomes by its association with H3K9 methyltransferases SUV39H1 and GLP. elife. 2019;8: pubmed publisher
Sun H, England C, Hernandez R, Graves S, Majewski R, Kamkaew A, et al. ImmunoPET for assessing the differential uptake of a CD146-specific monoclonal antibody in lung cancer. Eur J Nucl Med Mol Imaging. 2016;43:2169-2179 pubmed publisher
product information
brand :
Novus
master code :
NBP2-44512
SKU :
NBP2-44512-0.02mg
product name :
MCAM/CD146 Antibody (MUC18/1130)
description :
The MCAM/CD146 Antibody (MUC18/1130) from Novus Biologicals is a mouse monoclonal antibody to MCAM/CD146. This antibody reacts with human. The MCAM/CD146 Antibody (MUC18/1130) has been validated for the following applications: Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence.
target :
MCAM/CD146
category :
Primary Antibodies
unit size :
0.02 mg
buffer :
10 mM PBS with 0.05% BSA
clonality :
Monoclonal
clone :
MUC18/1130
concentration :
0.2 mg/ml
conjugate :
Unconjugated
host :
Mouse
immunogen :
Recombinant human MUC18 protein
isotype :
IgG1 Kappa
purity :
Protein A or G purified
species :
Human
specificity :
The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2+-independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. Mel-CAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease.
theoretical molecular weight :
130 kDa
gene symbol :
MCAM
catalog number base :
NBP2-44512
accessionNumbers :
P43121
applications :
Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence
2020 USD :
129
2021 USD :
149 USD
alt names :
CD146, CD146 antigen, cell surface glycoprotein MUC18, Cell surface glycoprotein P1H12, melanoma adhesion molecule, melanoma cell adhesion moleculeS-endo 1 endothelial-associated antigen, Melanoma-associated antigen A32, Melanoma-associated antigen MUC18, MUC18Gicerin
storage :
Store at 4C.
company information
Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.