SUMO2 Antibody (SUMO2/1199) | Novus Biologicals NBP2-44477 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

SUMO2 Antibody (SUMO2/1199)

catalog :

NBP2-44477

quantity :

0.02 mg

price :

149 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

SUMO2/1199

reactivity :

human, rat

application :

immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

citations: 2

Reference
Shekarian T, Sivadó É, Jallas A, Depil S, Kielbassa J, Janoueix Lerosey I, et al. Repurposing rotavirus vaccines for intratumoral immunotherapy can overcome resistance to immune checkpoint blockade. Sci Transl Med. 2019;11: pubmed publisher
Frasca L, Palazzo R, Chimenti M, Alivernini S, Tolusso B, Bui L, et al. Anti-LL37 Antibodies Are Present in Psoriatic Arthritis (PsA) Patients: New Biomarkers in PsA. Front Immunol. 2018;9:1936 pubmed publisher

product information

brand :

Novus

master code :

NBP2-44477

SKU :

NBP2-44477-0.02mg

product name :

SUMO2 Antibody (SUMO2/1199)

description :

The SUMO2 Antibody (SUMO2/1199) from Novus Biologicals is a mouse monoclonal antibody to SUMO2. This antibody reacts with human, rat. The SUMO2 Antibody (SUMO2/1199) has been validated for the following applications: Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence.

target :

SUMO2

category :

Primary Antibodies

unit size :

0.02 mg

buffer :

10 mM PBS with 0.05% BSA

clonality :

Monoclonal

clone :

SUMO2/1199

concentration :

0.2 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

Recombinant human SUMO2 protein

isotype :

IgG1 Kappa

purity :

Protein A or G purified

species :

Human, Rat

specificity :

The small ubiquitin-related modifier (SUMO) proteins, which include SUMO-1, 2 and 3, belong to the ubiquitin-like protein family. Like ubiquitin, the SUMO proteins are synthesized as precursor proteins that undergo processing before conjugation to target proteins. Also, both utilize the E1, E2 and E3 cascade enzymes for conjugation. However, SUMO and ubiquitin differ with respect to targeting. Ubiquitination predominantly targets proteins for degradation, whereas sumoylation targets proteins to a variety of cellular processing, including nuclear transport, transcriptional regulation, apoptosis and protein stability. The unconjugated SUMO-1, 2 and 3 proteins localize to the nuclear membrane, nuclear bodies and cytoplasm, respectively. SUMO-1 utilizes Ubc9 for conjugation to several target proteins, which include MDM2, p53, PML and RanGap1. SUMO-2 and 3 contribute to a greater percentage of protein modification than does SUMO-1 and unlike SUMO-1, they can form polymeric chains. In addition, SUMO-3 regulates beta-Amyloid generation and may be critical in the onset or progression of Alzheimer s disease.

theoretical molecular weight :

12 kDa

gene symbol :

SUMO2

catalog number base :

NBP2-44477

accessionNumbers :

P55854

applications :

Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence

2020 USD :

129

2021 USD :

149 USD

alt names :

HSMT3, MGC117191, sentrin 2, Sentrin-2, small ubiquitin-like modifier 2, small ubiquitin-related modifier 2, SMT3 (suppressor of mif two 3, yeast) homolog 2, SMT3 homolog 2, SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae), SMT3 suppressor of mif two 3 homolog 2 (yeast), SMT3A, SMT3B, SMT3H2, SUMO-2, SUMO3, SUMO-3, Ubiquitin-like protein SMT3A, ubiquitin-like protein SMT3B

storage :

Store at 4C.