This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
PINK1 Antibody (8E10.1D6) - BSA Free
catalog :
NBP2-36488
quantity :
0.1 mg (also 0.025 mg)
price :
429 USD
clonality :
monoclonal
host :
mouse
conjugate :
DyLight 594
clone name :
8E10.1D6
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
citations: 10
Reference
Tufi R, Clark E, Hoshikawa T, Tsagkaraki C, Stanley J, Takeda K, et al. High-content phenotypic screen to identify small molecule enhancers of Parkin-dependent ubiquitination and mitophagy. SLAS Discov. 2023;28:73-87 pubmed publisher
Di Rienzo M, Romagnoli A, Ciccosanti F, Refolo G, Consalvi V, Arena G, et al. AMBRA1 regulates mitophagy by interacting with ATAD3A and promoting PINK1 stability. Autophagy. 2021;:1-11 pubmed publisher
Meng Q, Zaharieva E, Sasatani M, Kobayashi J. Possible relationship between mitochondrial changes and oxidative stress under low dose-rate irradiation. Redox Rep. 2021;26:160-169 pubmed publisher
Shin N, Shin H, Yi Y, Beom J, Lee W, Lee C, et al. p66shc siRNA-Encapsulated PLGA Nanoparticles Ameliorate Neuropathic Pain Following Spinal Nerve Ligation. Polymers (Basel). 2020;12: pubmed publisher
Han H, Chou C, Li R, Liu J, Zhang L, Zhu W, et al. Chalcomoracin is a potent anticancer agent acting through triggering Oxidative stress via a mitophagy- and paraptosis-dependent mechanism. Sci Rep. 2018;8:9566 pubmed publisher
Piao Y, Gwon D, Kang D, Hwang T, Shin N, Kwon H, et al. TLR4-mediated autophagic impairment contributes to neuropathic pain in chronic constriction injury mice. Mol Brain. 2018;11:11 pubmed publisher
Kim M, Hwang J, Yun C, Lee Y, Choi Y. Delivery of exogenous mitochondria via centrifugation enhances cellular metabolic function. Sci Rep. 2018;8:3330 pubmed publisher
Tan W, Song L, Graham M, Schettino A, Navaratnam D, Yarbrough W, et al. Novel Role of the Mitochondrial Protein Fus1 in Protection from Premature Hearing Loss via Regulation of Oxidative Stress and Nutrient and Energy Sensing Pathways in the Inner Ear. Antioxid Redox Signal. 2017;27:489-509 pubmed publisher
Ko J, Park J, Park Y, Koh H. PPAR-? activation attenuates deltamethrin-induced apoptosis by regulating cytosolic PINK1 and inhibiting mitochondrial dysfunction. Toxicol Lett. 2016;260:8-17 pubmed publisher
Greene A, Grenier K, Aguileta M, Muise S, Farazifard R, Haque M, et al. Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment. EMBO Rep. 2012;13:378-85 pubmed publisher
product information
brand :
Novus Biologicals, a Bio-Techne brand
catalog number base :
NBP2-36488
SKU :
NBP2-36488
product name :
PINK1 Antibody (8E10.1D6) - BSA Free
description :
The PINK1 Antibody (8E10.1D6) - BSA Free from Novus Biologicals is a mouse monoclonal antibody to PINK1. This antibody reacts with human,mouse,rat. The PINK1 Antibody (8E10.1D6) - BSA Free has been validated for the following applications: Immunohistochemistry,SDS-Page,Knockdown Validated,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence.
target :
PINK1
unit size :
0.1 mg (also 0.025 mg)
category :
Primary Antibodies
buffer :
PBS
clonality :
Monoclonal
clone :
8E10.1D6
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Mouse
immunogen :
PINK1 antibody was developed using a synthetic peptide made to the human PINK1 protein sequence (between residues 100-250). [Swiss-Prot: Q9BXM7]
isotype :
IgG2b Kappa
purity :
Protein G purified
species :
Human,Mouse,Rat
specificity :
Human PINK1 protein sequence (between residues 100-250), only reactive to isoform 1
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
theoretical molecular weight :
62.7 kDa
gene symbol :
PINK1
Antibody validation :
Biological Validation
accessionNumbers :
Q9BXM7
applications :
Immunohistochemistry,SDS-Page,Knockdown Validated,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence
USD :
409
USD 2025 :
429 USD
alt names :
BRPK, EC 2.7.11.1, FLJ27236, PARK6, Parkinson disease (autosomal recessive) 6, PINK1 monoclonal, protein kinase BRPK, PTEN Induced Kinase 1, PTEN induced putative kinase 1, PTEN-induced putative kinase protein 1, serine/threonine-protein kinase PINK1, mitochondrial
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.