alpha-Smooth Muscle Actin Antibody (1A4/asm-1) - Azide and BSA Free | Novus Biologicals NBP2-34522 product information

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product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

alpha-Smooth Muscle Actin Antibody (1A4/asm-1) - Azide and BSA Free

catalog :

NBP2-34522

quantity :

0.1 mg (also 0.2 mg)

price :

329 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1A4/asm-1

reactivity :

human, mouse, rat, dogs, chicken, bovine

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

citations: 5

Reference
Hreha T, Collins C, Daugherty A, Twentyman J, Paluri N, Hunstad D. TGFβ1 orchestrates renal fibrosis following Escherichia coli pyelonephritis. Physiol Rep. 2020;8:e14401 pubmed publisher
Bloodworth N, Clark C, West J, Snider J, Gaskill C, Shay S, et al. Bone Marrow-Derived Proangiogenic Cells Mediate Pulmonary Arteriole Stiffening via Serotonin 2B Receptor Dependent Mechanism. Circ Res. 2018;123:e51-e64 pubmed publisher
Bowler M, Bersi M, Ryzhova L, Jerrell R, Parekh A, Merryman W. Cadherin-11 as a regulator of valve myofibroblast mechanobiology. Am J Physiol Heart Circ Physiol. 2018;315:H1614-H1626 pubmed publisher
Hirata Y, Aoki H, Shojima T, Takagi K, Takaseya T, Akasu K, et al. Activation of the AKT Pathway in the Ascending Aorta With Bicuspid Aortic Valve. Circ J. 2018;82:2485-2492 pubmed publisher
Guzy R, Li L, Smith C, Dorry S, Koo H, Chen L, et al. Pulmonary fibrosis requires cell-autonomous mesenchymal fibroblast growth factor (FGF) signaling. J Biol Chem. 2017;292:10364-10378 pubmed publisher

product information

brand :

Novus

master code :

NBP2-34522

SKU :

NBP2-34522-0.1 mg

product name :

alpha-Smooth Muscle Actin Antibody (1A4/asm-1) - Azide and BSA Free

description :

The alpha-Smooth Muscle Actin Antibody (1A4/asm-1) - Azide and BSA Free from Novus Biologicals is a mouse monoclonal antibody to alpha-Smooth Muscle Actin. This antibody reacts with human, mouse, rat, porcine, bovine, canine, chicken, feline, guinea pig, goat, baboon, monkey, rabbit, sheep. The alpha-Smooth Muscle Actin Antibody (1A4/asm-1) - Azide and BSA Free has been validated for the following applications: Western Blot, Simple Western, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Flow (Intracellular), CyTOF-ready.

target :

alpha-Smooth Muscle Actin

category :

Primary Antibodies

unit size :

0.1 mg (also 0.2 mg)

buffer :

PBS

clonality :

Monoclonal

clone :

1A4/asm-1

concentration :

1.0 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

Alpha-Smooth Muscle Actin Antibody (1A4/asm-1) is made to the N-Terminal decapeptide of Alpha smooth muscle isoform of actin and conjugated to KLH.

isotype :

IgG2a Kappa

purity :

Protein A purified

species :

Human, Mouse, Rat, Porcine, Bovine, Canine, Chicken, Feline, Guinea Pig, Goat, Baboon, Monkey, Rabbit, Sheep

specificity :

Actin is a major component of the cytoskeleton and is present in most cell types. This MAb is highly specific to actin from smooth muscles. Its epitope lies in the first four N-terminal amino acids. This MAb does not stain cardiac or skeletal muscle; however, it does stain myofibroblasts and myoepithelial cells. This antibody could be used together with anti-muscle specific actin and myogenin in making a diagnosis of smooth muscle and skeletal muscle tumors. In most cases of rhabdomyosarcoma, this antibody yields negative results whereas anti-muscle specific actin and myogenin are positive. Leiomyosarcomas are positive only with anti-muscle specific actin and anti-smooth muscle actin and are negative with anti-myogenin.

theoretical molecular weight :

42 kDa

gene symbol :

ACTA2

catalog number base :

NBP2-34522

applications :

Western Blot, Simple Western, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Flow (Intracellular), CyTOF-ready

2020 USD :

329

2021 USD :

329 USD

alt names :

AAT6, actin, alpha 2, smooth muscle, aorta, actin, aortic smooth muscle, ACTSA, ACTVS, alpha 2 actin, alpha SMA, alpha smooth muscle actin, alpha-actin-2, alpha-SMA, a-sma, Cell growth-inhibiting gene 46 protein, growth-inhibiting gene 46, sma, smooth muscle actin

storage :

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.