TFF1/pS2 Antibody (GE2 (same as R47/94)) | Novus Biologicals NBP2-34293 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

TFF1/pS2 Antibody (GE2 (same as R47/94))

catalog :

NBP2-34293

quantity :

0.02 mg

price :

149 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

GE2 (same as R47/94)

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

product information

brand :

Novus

master code :

NBP2-34293

SKU :

NBP2-34293-0.02mg

product name :

TFF1/pS2 Antibody (GE2 (same as R47/94))

description :

The TFF1/pS2 Antibody (GE2 (same as R47/94)) from Novus Biologicals is a mouse monoclonal antibody to TFF1/pS2. This antibody reacts with human, primate. The TFF1/pS2 Antibody (GE2 (same as R47/94)) has been validated for the following applications: Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.

target :

TFF1/pS2

category :

Primary Antibodies

unit size :

0.02 mg

buffer :

10 mM PBS with 0.05% BSA

clonality :

Monoclonal

clone :

GE2 (same as R47/94)

concentration :

0.2 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

Synthetic peptide of 28 amino acid residues corresponding to CFDDTVRGVPWCFYPNTIDVPPEEECEF (aa57-84) from the C-terminus of human pS2.

isotype :

IgG1 Kappa

purity :

Protein A purified

species :

Human, Primate

specificity :

It recognizes a polypeptide of 6.5kDa, identified as pS2 estrogen-regulated protein. Its epitope is localized between aa57-84 of human pS2 protein. pS2 is a trefoil peptide. Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intra-chain disulfide bonds, forming the trefoil motif, or P-domain. pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties. About 60% of breast carcinomas are positive for pS2. Staining is cytoplasmic, often with localization to the Golgi apparatus. pS2 is shown to be localized in normal stomach mucosa, gastric fluid, goblet cells in the colon and small intestine, and in ulcerations of the gastrointestinal tract. Several studies have shown that pS2 is primarily expressed in estrogen receptor-positive breast tumors and it may define a subset of estrogen-dependent tumors that displays an increased likelihood of response to endocrine therapy.

theoretical molecular weight :

6.5 kDa

gene symbol :

TFF1

catalog number base :

NBP2-34293

accessionNumbers :

P04155

applications :

Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

2020 USD :

129

2021 USD :

149 USD

alt names :

BCEIbreast cancer, estrogen-inducible sequence expressed in, Breast cancer estrogen-inducible protein, breast cancer estrogen-inducible sequence, D21S21, gastrointestinal trefoil protein pS2, hP1.A, HPS2, pNR-2, Polypeptide P1.A, Protein pS2, pS2, trefoil factor 1, trefoil factor, BCE1, human pS2 induced by estrogen from human breast cancercell line M10HP1.A

storage :

Store at 4C.