This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
SUMO2/3 Antibody (SM23/496)
catalog :
NBP2-34292
quantity :
0.02 mg
price :
149 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
SM23/496
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
product information
brand :
Novus
master code :
NBP2-34292
SKU :
NBP2-34292-0.02mg
product name :
SUMO2/3 Antibody (SM23/496)
description :
The SUMO2/3 Antibody (SM23/496) from Novus Biologicals is a mouse monoclonal antibody to SUMO2/3. This antibody reacts with human. The SUMO2/3 Antibody (SM23/496) has been validated for the following applications: Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Flow (Intracellular).
target :
SUMO2/3
category :
Primary Antibodies
unit size :
0.02 mg
buffer :
10 mM PBS with 0.05% BSA
clonality :
Monoclonal
clone :
SM23/496
concentration :
0.2 mg/ml
conjugate :
Unconjugated
host :
Mouse
immunogen :
Recombinant human SUMO2 protein
isotype :
IgG1 Kappa
purity :
Protein A purified
species :
Human
specificity :
This MAb reacts with both SUMO-2 and SUMO-3. The small ubiquitin-related modifier (SUMO) proteins, which include SUMO-1, 2 and 3, belong to the ubiquitin-like protein family. Like ubiquitin, the SUMO proteins are synthesized as precursor proteins that undergo processing before conjugation to target proteins. Also, both utilize the E1, E2 and E3 cascade enzymes for conjugation. However, SUMO and ubiquitin differ with respect to targeting. Ubiquitination predominantly targets proteins for degradation, whereas sumoylation targets proteins to a variety of cellular processing, including nuclear transport, transcriptional regulation, apoptosis and protein stability. The unconjugated SUMO-1, 2 and 3 proteins localize to the nuclear membrane, nuclear bodies and cytoplasm, respectively. SUMO-1 utilizes Ubc9 for conjugation to several target proteins, which include MDM2, p53, PML and RanGap1. SUMO-2 and 3 contribute to a greater percentage of protein modification than does SUMO-1 and unlike SUMO-1, they can form polymeric chains. In addition, SUMO-3 regulates beta-Amyloid generation and may be critical in the onset or progression of Alzheimer's disease.
gene symbol :
SUMO2
catalog number base :
NBP2-34292
accessionNumbers :
P61956
applications :
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Flow (Intracellular)
2020 USD :
129
2021 USD :
149 USD
alt names :
HSMT3, small ubiquitin-like modifier 2, SMT3A, SMT3B, SMT3H2, SUMO2, SUMO3
storage :
Store at 4C.
company information
Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.