L1CAM Antibody (UJ127) - Azide and BSA Free | Novus Biologicals NBP2-34273 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

L1CAM Antibody (UJ127) - Azide and BSA Free

catalog :

NBP2-34273

quantity :

0.1 mg

price :

329 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

UJ127

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section

citations: 2

Reference
Ganesh K, Basnet H, Kaygusuz Y, Laughney A, He L, Sharma R, et al. L1CAM defines the regenerative origin of metastasis-initiating cells in colorectal cancer. Nat Cancer. 2020;1:28-45 pubmed publisher
Suh D, Kim M, Kim H, Chung H, Park N, Song Y, et al. L1 cell adhesion molecule expression is associated with pelvic lymph node metastasis and advanced stage in diabetic patients with endometrial cancer: a matched case control study. J Cancer Prev. 2014;19:231-9 pubmed publisher

product information

brand :

Novus

master code :

NBP2-34273

SKU :

NBP2-34505-0.1 mg

product name :

L1CAM Antibody (UJ127) - Azide and BSA Free

description :

The L1CAM Antibody (UJ127) - Azide and BSA Free from Novus is a mouse monoclonal antibody to L1CAM. This antibody reacts with human. The L1CAM Antibody (UJ127) - Azide and BSA Free has been validated for the following applications: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Frozen, CyTOF-ready.

target :

L1CAM

category :

Primary Antibodies

unit size :

0.1 mg

buffer :

10 mM PBS

clonality :

Monoclonal

clone :

UJ127

concentration :

1.0 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

Homogenous suspension of 16 week human fetal brain

isotype :

IgG1 Kappa

purity :

Protein A purified

species :

Human

specificity :

Recognizes a cell surface protein of 220-240kDa, identified as L1 cell adhesion molecule. The L1CAM gene, which is located in Xq28, is involved in three distinct conditions: 1) HSAS (hydrocephalus-stenosis of the aqueduct of Sylvius); 2) MASA (mental retardation, aphasia, shuffling gait, and adducted thumbs); and 3) SPG1 (spastic paraplegia). The L1, neural cell adhesion molecule (L1CAM) also plays an important role in axon growth, fasciculation, and neural migration as well as in mediating neuronal differentiation. Expression of L1 protein is restricted to tissues arising from neuroectoderm. This MAb is useful in the identification of primitive neuroectodermal tumors. It binds to tumors of neuroectodermal and glial origin e.g. neuroblastoma and Schwannomas. It does not bind to pediatric or adult brain.

theoretical molecular weight :

230 kDa

gene symbol :

L1CAM

catalog number base :

NBP2-34505

applications :

Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Frozen, CyTOF-ready

USD :

329 USD

alt names :

antigen identified by monoclonal R1, CAML1N-CAML1, CD171, CD171 antigen, HSAS, HSAS1, L1 cell adhesion molecule, MASA, MIC5, N-CAM-L1, NCAM-L1, neural cell adhesion molecule L1, S10, SPG1

storage :

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.