Insulin Antibody (E2-E3 (same as INS04)) | Novus Biologicals NBP2-34260 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

Insulin Antibody (E2-E3 (same as INS04))

catalog :

NBP2-34260

quantity :

0.02 mg

price :

149 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

E2-E3 (same as INS04)

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

citations: 4

Reference
Ahlers L, Trammell C, Carrell G, Mackinnon S, Torrevillas B, Chow C, et al. Insulin Potentiates JAK/STAT Signaling to Broadly Inhibit Flavivirus Replication in Insect Vectors. Cell Rep. 2019;29:1946-1960.e5 pubmed publisher
Xiao C, Wu G, Zhou Z, Zhang X, Wang Y, Song G, et al. RBBP6, a RING finger-domain E3 ubiquitin ligase, induces epithelial-mesenchymal transition and promotes metastasis of colorectal cancer. Cell Death Dis. 2019;10:833 pubmed publisher
Monchusi B, Ntwasa M. Methyl pyruvate protects a normal lung fibroblast cell line from irinotecan-induced cell death: Potential use as adjunctive to chemotherapy. PLoS ONE. 2017;12:e0182789 pubmed publisher
Kishikawa T, Otsuka M, Yoshikawa T, Ohno M, Ijichi H, Koike K. Satellite RNAs promote pancreatic oncogenic processes via the dysfunction of YBX1. Nat Commun. 2016;7:13006 pubmed publisher

product information

brand :

Novus

master code :

NBP2-34260

SKU :

NBP2-34260-0.02mg

product name :

Insulin Antibody (E2-E3 (same as INS04))

description :

The Insulin Antibody (E2-E3 (same as INS04)) from Novus Biologicals is a mouse monoclonal antibody to Insulin. This antibody reacts with human, mouse, porcine, bovine, rabbit. The Insulin Antibody (E2-E3 (same as INS04)) has been validated for the following applications: Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.

target :

Insulin

category :

Primary Antibodies

unit size :

0.02 mg

buffer :

10 mM PBS with 0.05% BSA

clonality :

Monoclonal

clone :

E2-E3 (same as INS04)

concentration :

0.2 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

Full length (1-84 amino acid) purified pig insulin, conjugated to KLH

isotype :

IgG1 Kappa

purity :

Protein A purified

species :

Human, Mouse, Porcine, Bovine, Rabbit

specificity :

Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.

theoretical molecular weight :

6 kDa

gene symbol :

INS

catalog number base :

NBP2-34260

accessionNumbers :

P01308

applications :

Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

2020 USD :

129

2021 USD :

149 USD

alt names :

IDDM2, ILPR, insulin, IRDN, MODY10, proinsulin

storage :

Store at 4C.