Pax6 Antibody (PAX6/498) | Novus Biologicals NBP2-32893 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

Pax6 Antibody (PAX6/498)

catalog :

NBP2-32893

quantity :

0.02 mg

price :

149 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

PAX6/498

reactivity :

human, mouse, rat, chicken

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry

citations: 1

Reference
Poulin H, Martineau L, Racine V, Puymirat J, Chahine M. Differentiation of lymphoblastoid-derived iPSCs into functional cardiomyocytes, neurons and myoblasts. Biochem Biophys Res Commun. 2019;: pubmed publisher

product information

brand :

Novus

master code :

NBP2-32893

SKU :

NBP2-32893-0.02mg

product name :

Pax6 Antibody (PAX6/498)

description :

The Pax6 Antibody (PAX6/498) from Novus Biologicals is a mouse monoclonal antibody to Pax6. This antibody reacts with human, mouse, rat, chicken. The Pax6 Antibody (PAX6/498) has been validated for the following applications: Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Flow (Intracellular).

target :

Pax6

category :

Primary Antibodies

unit size :

0.02 mg

buffer :

10 mM PBS with 0.05% BSA

clonality :

Monoclonal

clone :

PAX6/498

concentration :

0.2 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

Recombinant fragment (N-terminus; aa 1-300) of human PAX6 protein

isotype :

IgG1 Kappa

purity :

Protein A purified

species :

Human, Mouse, Rat, Chicken

specificity :

Pax genes contain paired domains with strong homology to genes in Drosophila, which are involved in programming early development. Lesions in the Pax-6 gene account for most cases of aniridia, a congenital malformation of the eye, chiefly characterized by iris hypoplasia, which can cause blindness. Pax-6 is involved in other anterior segment malformations besides aniridia, such as Peters anomaly, a major error in the embryonic development of the eye with corneal clouding with variable iridolenticulocorneal adhesions. The Pax-6 gene encodes a transcriptional regulator that recognizes target genes through its paired-type DNA-binding domain. The paired domain is composed of two distinct DNA-binding subdomains, the amino-terminal subdomain and the carboxy-terminal subdomain, which bind respective consensus DNA sequences. The human Pax-6 gene produces two alternatively spliced isoforms that have the distinct structure of the paired domain.

theoretical molecular weight :

47 kDa

gene symbol :

PAX6

catalog number base :

NBP2-32893

accessionNumbers :

P26367

applications :

Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Flow (Intracellular)

2020 USD :

129

2021 USD :

149 USD

alt names :

keratitis), MGC17209, Oculorhombin, paired box 6, paired box protein Pax-6

storage :

Store at 4C.