Cyclin D1 Antibody (SPM587) | Novus Biologicals NBP2-32840 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

Cyclin D1 Antibody (SPM587)

catalog :

NBP2-32840

quantity :

0.02 mg

price :

149 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

SPM587

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section

citations: 6

Reference
Xu W, Chen S, Wang X, Wu H, Yamada H, Hirano T. Methylprednisolone potentiates tetrandrine pharmacodynamics against human T lymphoblastoid leukemia MOLT-4 cells via regulation of NF-κB activation and cell cycle transition. Steroids. 2020;163:108714 pubmed publisher
Xu W, Wu H, Chen S, Wang X, Tanaka S, Sugiyama K, et al. Cytotoxic effects of vitamins K1, K2 and K3 against human T lymphoblastoid leukemia cells through apoptosis induction and cell cycle arrest. Chem Biol Drug Des. 2020;: pubmed publisher
Padella A, Simonetti G, Paciello G, Giotopoulos G, Baldazzi C, Righi S, et al. Novel and Rare Fusion Transcripts Involving Transcription Factors and Tumor Suppressor Genes in Acute Myeloid Leukemia. Cancers (Basel). 2019;11: pubmed publisher
Robinson M, Maximov V, Lallani S, Farooq H, Taylor M, Read R, et al. Upregulation of the chromatin remodeler HELLS is mediated by YAP1 in Sonic Hedgehog Medulloblastoma. Sci Rep. 2019;9:13611 pubmed publisher
Digilio L, Yap C, Winckler B. Ctip2-, Satb2-, Prox1-, and GAD65-Expressing Neurons in Rat Cultures: Preponderance of Single- and Double-Positive Cells, and Cell Type-Specific Expression of Neuron-Specific Gene Family Members, Nsg-1 (NEEP21) and Nsg-2 (P19). PLoS ONE. 2015;10:e0140010 pubmed publisher
Chelsky Z, Yue P, Kondratyuk T, Paladino D, Pezzuto J, Cushman M, et al. A Resveratrol Analogue Promotes ERKMAPK-Dependent Stat3 Serine and Tyrosine Phosphorylation Alterations and Antitumor Effects In Vitro against Human Tumor Cells. Mol Pharmacol. 2015;88:524-33 pubmed publisher

product information

brand :

Novus

master code :

NBP2-32840

SKU :

NBP2-32840-0.02mg

product name :

Cyclin D1 Antibody (SPM587)

description :

The Cyclin D1 Antibody (SPM587) from Novus Biologicals is a mouse monoclonal antibody to Cyclin D1. This antibody reacts with human, mouse, rat, primate. The Cyclin D1 Antibody (SPM587) has been validated for the following applications: Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin.

target :

Cyclin D1

category :

Primary Antibodies

unit size :

0.02 mg

buffer :

10 mM PBS with 0.05% BSA

clonality :

Monoclonal

clone :

SPM587

concentration :

0.2 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

Human recombinant full length cyclin D1 protein

isotype :

IgG2a Kappa

purity :

Protein A purified

species :

Human, Mouse, Rat, Primate

specificity :

Recognizes a protein of 36kDa, identified as cyclin D1. Cyclin D1, one of the key cell cycle regulators, is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. This antibody neutralizes the activity of cyclin D1 in vivo. About 60% of mantle cell lymphomas (MCL) contain a t(11; 14)(q13; q32) translocation resulting in over-expression of cyclin D1. This antibody is useful in identifying mantle cell lymphomas (cyclin D1 positive) from CLL/SLL and follicular lymphomas (cyclin D1 negative). Occasionally, hairy cell leukemia and plasma cell myeloma weakly express Cyclin D1.

theoretical molecular weight :

36 kDa

gene symbol :

CCND1

catalog number base :

NBP2-32840

accessionNumbers :

P24385, P24385, P25322, P39948

applications :

Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin

2020 USD :

129

2021 USD :

149 USD

alt names :

B-cell lymphoma 1 protein, BCL-1, BCL-1 oncogene, BCL1D11S287E, cyclin D1, cyclin D1 (PRAD1: parathyroid adenomatosis 1), G1/S-specific cyclin D1, G1/S-specific cyclin-D1, PRAD1 oncogene, PRAD1B-cell CLL/lymphoma 1, U21B31

storage :

Store at 4C.