product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Cyclin D1 Antibody (SPM587)
catalog :
NBP2-32840-0.1mg
quantity :
0.1 mg (also 0.02 mg)
price :
419 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
SPM587
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 9
Reference
Cai Z, Wang J, Li Y, Shi Q, Jin L, Li S, et al. Overexpressed Cyclin D1 and CDK4 proteins are responsible for the resistance to CDK4/6 inhibitor in breast cancer that can be reversed by PI3K/mTOR inhibitors. Sci China Life Sci. 2023;66:94-109 pubmed publisher
Ding Z, Qiu M, Alharbi M, Huang T, Pei X, Milovanova T, et al. FOXO1 expression in chondrocytes modulates cartilage production and removal in fracture healing. Bone. 2021;148:115905 pubmed publisher
Shaalan A, Teshima T, Tucker A, Proctor G. Inhibition of Aurora Kinase B activity disrupts development and differentiation of salivary glands. Cell Death Discov. 2021;7:16 pubmed publisher
Gül H, Ilhan N, Ilhan N, Ozercan I, Kuloglu T. The combined effect of pomegranate extract and tangeretin on the DMBA-induced breast cancer model. J Nutr Biochem. 2021;89:108566 pubmed publisher
Shi Q, Li Y, Li S, Jin L, Lai H, Wu Y, et al. LncRNA DILA1 inhibits Cyclin D1 degradation and contributes to tamoxifen resistance in breast cancer. Nat Commun. 2020;11:5513 pubmed publisher
Xu W, Chen S, Wang X, Wu H, Yamada H, Hirano T. Methylprednisolone potentiates tetrandrine pharmacodynamics against human T lymphoblastoid leukemia MOLT-4 cells via regulation of NF-κB activation and cell cycle transition. Steroids. 2020;163:108714 pubmed publisher
Xu W, Wu H, Chen S, Wang X, Tanaka S, Sugiyama K, et al. Cytotoxic effects of vitamins K1, K2 and K3 against human T lymphoblastoid leukemia cells through apoptosis induction and cell cycle arrest. Chem Biol Drug Des. 2020;: pubmed publisher
Robinson M, Maximov V, Lallani S, Farooq H, Taylor M, Read R, et al. Upregulation of the chromatin remodeler HELLS is mediated by YAP1 in Sonic Hedgehog Medulloblastoma. Sci Rep. 2019;9:13611 pubmed publisher
Chelsky Z, Yue P, Kondratyuk T, Paladino D, Pezzuto J, Cushman M, et al. A Resveratrol Analogue Promotes ERKMAPK-Dependent Stat3 Serine and Tyrosine Phosphorylation Alterations and Antitumor Effects In Vitro against Human Tumor Cells. Mol Pharmacol. 2015;88:524-33 pubmed publisher
product information
master code :
NBP2-32840
SKU :
NBP2-32840-0.1mg
product name :
Cyclin D1 Antibody (SPM587)
unit size :
0.1 mg (also 0.02 mg)
description :
The Cyclin D1 Antibody (SPM587) from Novus is a mouse monoclonal antibody to Cyclin D1. This antibody reacts with human,monkey,mouse,rat. The Cyclin D1 Antibody (SPM587) has been validated for the following applications: Immunohistochemistry,Flow Cytometry,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence.
target :
Cyclin D1
category :
Primary Antibodies
buffer :
10 mM PBS with 0.05% BSA
clonality :
Monoclonal
clone :
SPM587
concentration :
0.2 mg/ml
conjugate :
Unconjugated
host :
Mouse
immunogen :
Human recombinant full length cyclin D1 protein (Uniprot: P24385)
isotype :
IgG2a Kappa
purity :
Protein A or G purified
species :
Human,Monkey,Mouse,Rat
specificity :
Recognizes a protein of 36kDa, identified as cyclin D1
theoretical molecular weight :
36 kDa
gene symbol :
CCND1
Antibody validation :
Biological Validation
accessionNumbers :
P24385, P24385, P25322, P39948, P24385, P24385
applications :
Immunohistochemistry,Flow Cytometry,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence
USD :
419 USD
alt names :
B-cell lymphoma 1 protein, BCL-1, BCL-1 oncogene, BCL1D11S287E, cyclin D1, cyclin D1 (PRAD1: parathyroid adenomatosis 1), G1/S-specific cyclin D1, G1/S-specific cyclin-D1, PRAD1 oncogene, PRAD1B-cell CLL/lymphoma 1, U21B31
storage :
Store at 4C.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.