CD63 Antibody (NKI/C3) | Novus Biologicals NBP2-32829 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

CD63 Antibody (NKI/C3)

catalog :

NBP2-32829

quantity :

0.02 mg

price :

149 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

NKI/C3

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section

citations: 2

Reference
Chen L, Feng Z, Yue H, Bazdar D, Mbonye U, Zender C, et al. Exosomes derived from HIV-1-infected cells promote growth and progression of cancer via HIV TAR RNA. Nat Commun. 2018;9:4585 pubmed publisher
Takawale A, Zhang P, Patel V, Wang X, Oudit G, Kassiri Z. Tissue Inhibitor of Matrix Metalloproteinase-1 Promotes Myocardial Fibrosis by Mediating CD63-Integrin ?1 Interaction. Hypertension. 2017;69:1092-1103 pubmed publisher

product information

brand :

Novus

master code :

NBP2-32829

SKU :

NBP2-32829-0.02mg

product name :

CD63 Antibody (NKI/C3)

description :

The CD63 Antibody (NKI/C3) from Novus Biologicals is a mouse monoclonal antibody to CD63. This antibody reacts with human, mouse. The CD63 Antibody (NKI/C3) has been validated for the following applications: Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin.

target :

CD63

category :

Primary Antibodies

unit size :

0.02 mg

buffer :

10 mM PBS with 0.05% BSA

clonality :

Monoclonal

clone :

NKI/C3

concentration :

0.2 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

Smooth plasma membrane fraction of MeWo cells

isotype :

IgG1 Kappa

purity :

Protein A or G purified

species :

Human, Mouse

specificity :

This MAb recognizes protein of 26kDa-60kDa, which is identified as CD63. Its epitope is different from that of MAb LAMP3/529. The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression.

gene symbol :

CD63

catalog number base :

NBP2-32829

accessionNumbers :

P08962, P08962

applications :

Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin

2020 USD :

129

2021 USD :

149 USD

alt names :

CD_antigen: CD63, CD63, CD63 antigen, CD63 antigen (melanoma 1 antigen), CD63 molecule, Granulophysin, LAMP-3, Lysosomal-associated membrane protein 3, lysosome-associated membrane glycoprotein 3, ME491, melanoma 1 antigen, Melanoma-associated antigen ME491, melanoma-associated antigen MLA1, MLA1, Ocular melanoma-associated antigen, OMA81H, Tetraspanin-30, tspan-30, Tspan30

storage :

Store at 4C.