alpha-Smooth Muscle Actin Antibody (SPM332) | Novus Biologicals NBP2-32808 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

alpha-Smooth Muscle Actin Antibody (SPM332)

catalog :

NBP2-32808

quantity :

0.02 mg

price :

149 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

SPM332

reactivity :

human, mouse, rat, dogs, chicken, bovine

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

citations: 7

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 5b	Kojima A, Sakaue T, Okazaki M, Shikata F, Kurata M, Imai Y, et al. A simple mouse model of pericardial adhesions. J Cardiothorac Surg. 2019;14:124 pubmed publisher
	Gremlich S, Roth Kleiner M, Equey L, Fytianos K, Schittny J, Cremona T. Tenascin-C inactivation impacts lung structure and function beyond lung development. Sci Rep. 2020;10:5118 pubmed publisher
	Wolf M, Clay S, Zheng S, Pan P, Chan M. MMP12 Inhibits Corneal Neovascularization and Inflammation through Regulation of CCL2. Sci Rep. 2019;9:11579 pubmed publisher
	Sakaue T, Nakaoka H, Shikata F, Aono J, Kurata M, Uetani T, et al. Biochemical and histological evidence of deteriorated bioprosthetic valve leaflets: the accumulation of fibrinogen and plasminogen. Biol Open. 2018;7: pubmed publisher
	Lang S, Harre U, Purohit P, Dietel K, Kienhöfer D, Hahn J, et al. Neurodegeneration Enhances the Development of Arthritis. J Immunol. 2017;198:2394-2402 pubmed publisher
	Carlson S, Helterline D, Asbe L, Dupras S, Minami E, Farris S, et al. Cardiac macrophages adopt profibrotic/M2 phenotype in infarcted hearts: Role of urokinase plasminogen activator. J Mol Cell Cardiol. 2017;108:42-49 pubmed publisher
	Zhang L, Zhang S, Yao J, Lowery F, Zhang Q, Huang W, et al. Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth. Nature. 2015;527:100-104 pubmed publisher

product information

brand :

Novus

master code :

NBP2-32808

SKU :

NBP2-32808-0.02mg

product name :

alpha-Smooth Muscle Actin Antibody (SPM332)

description :

The alpha-Smooth Muscle Actin Antibody (SPM332) from Novus Biologicals is a mouse monoclonal antibody to alpha-Smooth Muscle Actin. This antibody reacts with human, mouse, rat, porcine, bovine, canine, chicken, feline, guinea pig, goat, primate, baboon, rabbit, sheep. The alpha-Smooth Muscle Actin Antibody (SPM332) has been validated for the following applications: Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Flow (Intracellular).

target :

alpha-Smooth Muscle Actin

category :

Primary Antibodies

unit size :

0.02 mg

buffer :

10 mM PBS with 0.05% BSA

clonality :

Monoclonal

clone :

SPM332

concentration :

0.2 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

Alpha-Smooth Muscle Actin Antibody (SPM332) is made to the N-Terminal decapeptide of Alpha smooth muscle isoform of actin and conjugated to KLH.

isotype :

IgG2a Kappa

purity :

Protein A purified

species :

Human, Mouse, Rat, Porcine, Bovine, Canine, Chicken, Feline, Guinea Pig, Goat, Primate, Baboon, Rabbit, Sheep

specificity :

Actin is a major component of the cytoskeleton and is present in most cell types. This MAb is highly specific to actin from smooth muscles. Its epitope lies in the first four N-terminal amino acids. This MAb does not stain cardiac or skeletal muscle; however, it does stain myofibroblasts and myoepithelial cells. This antibody could be used together with anti-muscle specific actin and myogenin in making a diagnosis of smooth muscle and skeletal muscle tumors. In most cases of rhabdomyosarcoma, this antibody yields negative results whereas anti-muscle specific actin and myogenin are positive. Leiomyosarcomas are positive only with anti-muscle specific actin and anti-smooth muscle actin and are negative with anti-myogenin.

theoretical molecular weight :

42 kDa

gene symbol :

ACTA2

catalog number base :

NBP2-32808

accessionNumbers :

P62736

applications :

Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Flow (Intracellular)

2020 USD :

129

2021 USD :

149 USD

alt names :

AAT6, actin, alpha 2, smooth muscle, aorta, actin, aortic smooth muscle, ACTSA, ACTVS, alpha 2 actin, alpha SMA, alpha smooth muscle actin, alpha-actin-2, alpha-SMA, a-sma, Cell growth-inhibiting gene 46 protein, growth-inhibiting gene 46, sma, smooth muscle actin

storage :

Store at 4C.