product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
RNA Polymerase II/POLR2A Antibody - BSA Free
catalog :
NBP2-32080
quantity :
100 ul
price :
459 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
immunoprecipitation, chromatin immunoprecipitation
more info or order :
citations: 9
Reference
Tellier M, Ansa G, Murphy S. Isoginkgetin and Madrasin are poor splicing inhibitors. PLoS ONE. 2024;19:e0310519 pubmed publisher
Lyu Y, Yang Y, Talwar V, Lu H, Chen C, Salman S, et al. Hypoxia-inducible factor 1 recruits FACT and RNF20/40 to mediate histone ubiquitination and transcriptional activation of target genes. Cell Rep. 2024;43:113972 pubmed publisher
Akama Garren E, Miller P, Carroll T, Tellier M, Sutendra G, Buti L, et al. Regulation of immunological tolerance by the p53-inhibitor iASPP. Cell Death Dis. 2023;14:84 pubmed publisher
Guiro J, Fagbemi M, Tellier M, Zaborowska J, Barker S, Fournier M, et al. CAPTURE of the Human U2 snRNA Genes Expands the Repertoire of Associated Factors. Biomolecules. 2022;12: pubmed publisher
Yang Y, Lu H, Chen C, Lyu Y, Cole R, Semenza G. HIF-1 Interacts with TRIM28 and DNA-PK to release paused RNA polymerase II and activate target gene transcription in response to hypoxia. Nat Commun. 2022;13:316 pubmed publisher
Isa N, Bensaude O, Aziz N, Murphy S. HSV-1 ICP22 Is a Selective Viral Repressor of Cellular RNA Polymerase II-Mediated Transcription Elongation. Vaccines (Basel). 2021;9: pubmed publisher
Stavast C, Erkeland S. The Non-Canonical Aspects of MicroRNAs: Many Roads to Gene Regulation. Cells. 2019;8: pubmed publisher
Chirackal Manavalan A, Pilarova K, Kluge M, Bartholomeeusen K, Rajecky M, Oppelt J, et al. CDK12 controls G1/S progression by regulating RNAPII processivity at core DNA replication genes. EMBO Rep. 2019;20:e47592 pubmed publisher
Tellier M, Chalmers R. Human SETMAR is a DNA sequence-specific histone-methylase with a broad effect on the transcriptome. Nucleic Acids Res. 2019;47:122-133 pubmed publisher
product information
master code :
NBP2-32080
SKU :
NBP2-32080
product name :
RNA Polymerase II/POLR2A Antibody - BSA Free
unit size :
100 ul
description :
The RNA Polymerase II/POLR2A Antibody - BSA Free from Novus is a rabbit polyclonal antibody to RNA Polymerase II/POLR2A. This antibody reacts with human. The RNA Polymerase II/POLR2A Antibody - BSA Free has been validated for the following applications: Chemotaxis,Immunoprecipitation,Chromatin Immunoprecipitation (ChIP),Chromatin Immunoprecipitation Sequencing.
target :
RNA Polymerase II/POLR2A
category :
Primary Antibodies
buffer :
Tris-Citrate/Phosphate (pH 7.0 - 8.0)
clonality :
Polyclonal
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
The immunogen this antibody was made to, maps to a region between residue 754 to 804 of human RNA Polymerase II using the numbering given in entry NP_000928.1 (GeneID 5430).
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human
gene symbol :
POLR2A
accessionNumbers :
NP_000928.1
applications :
Chemotaxis,Immunoprecipitation,Chromatin Immunoprecipitation (ChIP),Chromatin Immunoprecipitation Sequencing
USD :
459 USD
alt names :
DNA-directed RNA polymerase II largest subunit, RNA polymerase II 220 kdsubunit, DNA-directed RNA polymerase II subunit A, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase III largest subunit, EC 2.7.7.48, EC 2.7.7.6, hRPB220, hsRPB1, MGC75453, POLR2, POLRA, polymerase (RNA) II (DNA directed) polypeptide A (220kD), polymerase (RNA) II (DNA directed) polypeptide A, 220kDa, RNA Pol 2, RNA Polymerase 2, RNA polymerase II subunit B1, RNA-directed RNA polymerase II subunit RPB1, RNAPII, RPB1, RPBh1, RpIILS, RPO2, RPOL2
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.