Mouse Monoclonal TLR4 Antibody (HTA125) [Alexa Fluor® 647] | Novus Biologicals NBP2-31197 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

Mouse Monoclonal TLR4 Antibody (HTA125) [Alexa Fluor® 647]

catalog :

NBP2-31197

quantity :

0.1 ml

price :

369 USD

clonality :

monoclonal

host :

mouse

conjugate :

AF647

clone name :

HTA125

reactivity :

human, dog

application :

western blot, immunocytochemistry, flow cytometry

citations: 8

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human	Mempel M, Voelcker V, Köllisch G, Plank C, Rad R, Gerhard M, et al. Toll-like receptor expression in human keratinocytes: nuclear factor kappaB controlled gene activation by Staphylococcus aureus is toll-like receptor 2 but not toll-like receptor 4 or platelet activating factor receptor dependent. J Invest Dermatol. 2003;121:1389-96 pubmed
	Cognasse F, Hamzeh H, Chavarin P, Acquart S, Genin C, Garraud O. Evidence of Toll-like receptor molecules on human platelets. Immunol Cell Biol. 2005;83:196-8 pubmed
	Wong C, Cheung P, Ip W, Lam C. Intracellular signaling mechanisms regulating toll-like receptor-mediated activation of eosinophils. Am J Respir Cell Mol Biol. 2007;37:85-96 pubmed
	Zanoni G, Navone R, Lunardi C, Tridente G, Bason C, Sivori S, et al. In celiac disease, a subset of autoantibodies against transglutaminase binds toll-like receptor 4 and induces activation of monocytes. PLoS Med. 2006;3:e358 pubmed
	Scheel O, Papavlassopoulos M, Blunck R, Gebert A, Hartung T, Zahringer U, et al. Cell activation by ligands of the toll-like receptor and interleukin-1 receptor family depends on the function of the large-conductance potassium channel MaxiK in human macrophages. Infect Immun. 2006;74:4354-6 pubmed
	Xu S, Koldovsky U, Xu M, Wang D, Fitzpatrick E, Son G, et al. High-avidity antitumor T-cell generation by toll receptor 8-primed, myeloid- derived dendritic cells is mediated by IL-12 production. Surgery. 2006;140:170-8 pubmed
	Prabha C, Rajashree P, Sulochana D. TLR2 and TLR4 expression on the immune cells of tuberculous pleural fluid. Immunol Lett. 2008;117:26-34 pubmed publisher
	Shahrara S, Park C, Temkin V, Jarvis J, Volin M, Pope R. RANTES modulates TLR4-induced cytokine secretion in human peripheral blood monocytes. J Immunol. 2006;177:5077-87 pubmed

product information

Catalog Number :

NBP2-31197

Product Name :

Mouse Monoclonal TLR4 Antibody (HTA125) [Alexa Fluor® 647]

List Price :

369 USD

product type :

Primary Antibodies

Package Size :

0.1 ml

AltNames :

ARMD10, CD284, CD284 antigen, hTollhomolog of Drosophila toll, TOLL, toll-like receptor 4

Buffer :

50mM Sodium Borate

Clonality :

Monoclonal

Clone :

HTA125

Conjugate :

Alexa Fluor 647

Application Summary :

Flow Cytometry, Immunocytochemistry/Immunofluorescence, Western Blot (Negative)

Host :

Mouse

Immunogen :

This antibody was developed by immunizing mice with Ba/F3 cell line expressing human TLR4 cell surface antigen.

Isotype :

IgG2a

Notes :

Alexa Flour (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. This product is provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com.

Preservative :

0.05% Sodium Azide

Purity :

Protein G purified

CrossReactivity :

Canine, Human

Specificity :

The has been shown to block the activation of monocytes with LPS (Paik, et al, 2003).

Storage :

Store at 4C in the dark.