product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Parkin Antibody (PRK8)
catalog :
NBP2-29838
quantity :
0.1 ml (also 0.025 ml)
price :
849 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
PRK8
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - frozen section
more info or order :
citations: 6
Reference
Reddy P, Kshirsagar S, Bose C, Pradeepkiran J, Hindle A, Singh S, et al. Rlip Reduction Induces Oxidative Stress and Mitochondrial Dysfunction in Mutant Tau-Expressed Immortalized Hippocampal Neurons: Mechanistic Insights. Cells. 2023;12: pubmed publisher
Zhao N, Zhang X, Li B, Wang J, Zhang C, Xu B. Treadmill Exercise Improves PINK1/Parkin-Mediated Mitophagy Activity Against Alzheimer's Disease Pathologies by Upregulated SIRT1-FOXO1/3 Axis in APP/PS1 Mice. Mol Neurobiol. 2023;60:277-291 pubmed publisher
Kshirsagar S, Alvir R, Pradeepkiran J, Hindle A, Vijayan M, Ramasubramaniam B, et al. A Combination Therapy of Urolithin A+EGCG Has Stronger Protective Effects than Single Drug Urolithin A in a Humanized Amyloid Beta Knockin Mice for Late-Onset Alzheimer's Disease. Cells. 2022;11: pubmed publisher
Zhang X, Lei Y, Xiao Y, Cao X, Tian X, Zhu Y, et al. Hen Egg Lysozyme Alleviates Static Mechanical Pain Via NRF1-Parkin-TACAN Signaling Axis in Sensory Neurons. Neuroscience. 2022;502:52-67 pubmed publisher
Kshirsagar S, Sawant N, Morton H, Reddy A, Reddy P. Mitophagy enhancers against phosphorylated Tau-induced mitochondrial and synaptic toxicities in Alzheimer disease. Pharmacol Res. 2021;174:105973 pubmed publisher
Chung E, Choi Y, Park J, Nah W, Park J, Jung Y, et al. Intracellular delivery of Parkin rescues neurons from accumulation of damaged mitochondria and pathological α-synuclein. Sci Adv. 2020;6:eaba1193 pubmed publisher
image
image 1 :
Novus Biologicals NBP2-29838 image 1
Western Blot: Parkin Antibody (PRK8) [NBP2-29838] - HEK293 cell lysate was probed with anti- Parkin, clone PRK8 (1:2000 dilution). Arrow indicates Parkin (~52kDa).
product information
brand :
Novus Biologicals, a Bio-Techne brand
catalog number base :
NBP2-29838
SKU :
NBP2-29838
product name :
Parkin Antibody (PRK8)
description :
The Parkin Antibody (PRK8) from Novus Biologicals is a mouse monoclonal antibody to Parkin. This antibody reacts with human,mouse. The Parkin Antibody (PRK8) has been validated for the following applications: Immunohistochemistry,Immunoprecipitation,Western Blot,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence.
target :
Parkin
unit size :
0.1 ml (also 0.025 ml)
category :
Primary Antibodies
buffer :
Ascites, containing 30% glycerol.
clonality :
Monoclonal
clone :
PRK8
conjugate :
Unconjugated
host :
Mouse
immunogen :
Full length recombinant human Parkin. Epitope has been mapped to the second ring domain (aa 399-465).
isotype :
IgG2b
purity :
Unpurified
species :
Human,Mouse
specificity :
Parkin 52kDa
storage :
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
gene symbol :
PRKN
accessionNumbers :
O60260
applications :
Immunohistochemistry,Immunoprecipitation,Western Blot,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence
USD :
829
USD 2025 :
849 USD
alt names :
E3 ubiquitin ligase, E3 ubiquitin-protein ligase parkin, EC 6.3.2.-, LPRS2, parkin, parkin 2, Parkinson disease protein 2, Parkinson juvenile disease protein 2, parkinson protein 2, E3 ubiquitin protein ligase (parkin), PDJjuvenile) 2, parkin
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.