KCC2/SLC12A5 [p Ser940] Antibody | Novus Biologicals NBP2-29513 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

KCC2/SLC12A5 [p Ser940] Antibody

catalog :

NBP2-29513

quantity :

0.1 ml

price :

409 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunoprecipitation

more info or order :

Novus Biologicals product webpage

citations: 4

Reference
Toritsuka M, Yoshino H, Makinodan M, Ikawa D, Kimoto S, Yamamuro K, et al. Developmental dysregulation of excitatory-to-inhibitory GABA-polarity switch may underlie schizophrenia pathology: A monozygotic-twin discordant case analysis in human iPS cell-derived neurons. Neurochem Int. 2021;150:105179 pubmed publisher
Barbour A, Nass S, Hahn Y, Hauser K, Knapp P. Restoration of KCC2 Membrane Localization in Striatal Dopamine D2 Receptor-Expressing Medium Spiny Neurons Rescues Locomotor Deficits in HIV Tat-Transgenic Mice. ASN Neuro. 2021;13:17590914211022089 pubmed publisher
Li J, Zhang L, Xu C, Lin Y, Zhang Y, Wu H, et al. Prolonged Use of NMDAR Antagonist Develops Analgesic Tolerance in Neuropathic Pain via Nitric Oxide Reduction-Induced GABAergic Disinhibition. Neurotherapeutics. 2020;17:1016-1030 pubmed publisher
Dumon C, Diabira D, Chudotvorova I, Bader F, Sahin S, Zhang J, et al. The adipocyte hormone leptin sets the emergence of hippocampal inhibition in mice. elife. 2018;7: pubmed publisher

image

image 1 :

Western Blot: KCC2/SLC12A5 [p Ser940] Antibody [NBP2-29513] - Rat hippocampal homogenate showing specific labeling of the ~ 135k KCC2 protein (Control). Immunolabeling is blocked by preadsorption with the phospho-peptide used as antigen (Peptide) but not by the corresponding dephospho-peptide (not shown).

product information

brand :

Novus Biologicals, a Bio-Techne brand

catalog number base :

NBP2-29513

SKU :

NBP2-29513

product name :

KCC2/SLC12A5 [p Ser940] Antibody

description :

The KCC2/SLC12A5 [p Ser940] Antibody from Novus Biologicals is a rabbit polyclonal antibody to KCC2/SLC12A5. This antibody reacts with human,mouse,rat. The KCC2/SLC12A5 [p Ser940] Antibody has been validated for the following applications: Immunoprecipitation,Western Blot.

target :

KCC2/SLC12A5

unit size :

0.1 ml

category :

Primary Antibodies

buffer :

10mM HEPES (pH 7.5), 0.15M NaCl, 0.1 mg/ml BSA and 50% Glycerol

clonality :

Polyclonal

conjugate :

Unconjugated

host :

Rabbit

immunogen :

Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser940 conjugated to KLH. Accession # Q63633

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse,Rat

specificity :

Specific for endogenous levels of the ~135 kDa KCC2/SLC12A5 protein phosphorylated at Ser940

storage :

Store at -20C. Avoid freeze-thaw cycles.

theoretical molecular weight :

135 kDa

gene symbol :

SLC12A5

accessionNumbers :

Q63633

applications :

Immunoprecipitation,Western Blot

USD :

399

USD 2025 :

409 USD

alt names :

Electroneutral potassium-chloride cotransporter 2, hKCC2, KCC2K-Cl cotransporter 2, KIAA1176erythroid K-Cl cotransporter 2, Neuronal K-Cl cotransporter, solute carrier family 12 (potassium/chloride transporter), member 5, solute carrier family 12 member 5

more info or order :

Novus Biologicals product webpage