AKT1 [p Ser473] Antibody (104A282) - Azide and BSA Free | Novus Biologicals NBP2-27399 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

AKT1 [p Ser473] Antibody (104A282) - Azide and BSA Free

catalog :

NBP2-27399

quantity :

0.1 mg (also 0.025 mg)

price :

409 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

104A282

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

more info or order :

Novus Biologicals product webpage

citations: 6

Reference
Wedel S, Hudak L, Seibel J, Juengel E, Tsaur I, Wiesner C, et al. Inhibitory effects of the HDAC inhibitor valproic acid on prostate cancer growth are enhanced by simultaneous application of the mTOR inhibitor RAD001. Life Sci. 2011;88:418-24 pubmed publisher
Wedel S, Hudak L, Seibel J, Juengel E, Oppermann E, Haferkamp A, et al. Critical analysis of simultaneous blockage of histone deacetylase and multiple receptor tyrosine kinase in the treatment of prostate cancer. Prostate. 2011;71:722-35 pubmed publisher
Elamin M, Shinwari Z, Hendrayani S, Al Hindi H, Al Shail E, Khafaga Y, et al. Curcumin inhibits the Sonic Hedgehog signaling pathway and triggers apoptosis in medulloblastoma cells. Mol Carcinog. 2010;49:302-14 pubmed publisher
Juengel E, Engler J, Natsheh I, Jones J, Mickuckyte A, Hudak L, et al. Combining the receptor tyrosine kinase inhibitor AEE788 and the mammalian target of rapamycin (mTOR) inhibitor RAD001 strongly inhibits adhesion and growth of renal cell carcinoma cells. BMC Cancer. 2009;9:161 pubmed publisher
Luty W, Rodeberg D, Parness J, Vyas Y. Antiparallel segregation of notch components in the immunological synapse directs reciprocal signaling in allogeneic Th:DC conjugates. J Immunol. 2007;179:819-29 pubmed
Nair A, Shishodia S, Ahn K, Kunnumakkara A, Sethi G, Aggarwal B. Deguelin, an Akt inhibitor, suppresses IkappaBalpha kinase activation leading to suppression of NF-kappaB-regulated gene expression, potentiation of apoptosis, and inhibition of cellular invasion. J Immunol. 2006;177:5612-22 pubmed

product information

master code :

NBP2-27399

SKU :

NBP2-27399

product name :

AKT1 [p Ser473] Antibody (104A282) - Azide and BSA Free

unit size :

0.1 mg (also 0.025 mg)

description :

The AKT1 [p Ser473] Antibody (104A282) - Azide and BSA Free from Novus is a mouse monoclonal antibody to AKT1. This antibody reacts with human,mouse,rabbit,rat. The AKT1 [p Ser473] Antibody (104A282) - Azide and BSA Free has been validated for the following applications: Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin.

target :

AKT1

category :

Primary Antibodies

buffer :

PBS

clonality :

Monoclonal

clone :

104A282

concentration :

1.0 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

This AKT1 phospho Ser473 monoclonal antibody was raised against a synthetic peptide containing phosphorylated serines at amino acid residues 473 of human Akt1.

isotype :

IgG1 Kappa

purity :

Protein G purified

species :

Human,Mouse,Rabbit,Rat

specificity :

Clone 104A282 detects specifically the Ser 473 phosphorylated form of AKT1

theoretical molecular weight :

55.7 kDa

gene symbol :

AKT1

Antibody validation :

Biological Validation

applications :

Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin

USD :

409 USD

alt names :

AKT, AKT serine/threonine kinase 1, AKT1m, CWS6, EC 2.7.11, EC 2.7.11.1, PKB, PKB alpha, PKBMGC99656, PRKBA, Protein kinase B, Protein Kinase B Alpha, Proto-oncogene c-Akt, RAC, rac protein kinase alpha, RAC-ALPHA, RAC-alpha serine/threonine-protein kinase, RAC-PK-alpha, RACPKB-ALPHA, Serine-Threonine Protein Kinase, v-akt murine thymoma viral oncogene homolog 1, V-Akt Murine Thymoma Viral Oncogene-Like Protein 1

storage :

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage