EBI3 Antibody (15k8D10) - BSA Free | Novus Biologicals NBP2-27362 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

EBI3 Antibody (15k8D10) - BSA Free

catalog :

NBP2-27362

quantity :

0.1 mg (also 0.025 mg)

price :

399 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

15k8D10

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Novus Biologicals product webpage

citations: 25

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; human; 1:300; loading ...; fig 2b	Ma Y, Chen L, Xie G, Zhou Y, Yue C, Yuan X, et al. Elevated level of interleukin-35 in colorectal cancer induces conversion of T cells into iTr35 by activating STAT1/STAT3. Oncotarget. 2016;7:73003-73015 pubmed publisher
immunohistochemistry - paraffin section; human	Mao H, Gao W, Ma C, Sun J, Liu J, Shao Q, et al. Human placental trophoblasts express the immunosuppressive cytokine IL-35. Hum Immunol. 2013;74:872-7 pubmed publisher
immunohistochemistry - paraffin section; human	Wang Z, Liu J, Liu Z, Shen R, Zhang G, Xu J, et al. Tumor-derived IL-35 promotes tumor growth by enhancing myeloid cell accumulation and angiogenesis. J Immunol. 2013;190:2415-23 pubmed publisher
	Ito T, Tanaka T, Nakamaru K, Tomiyama T, Yamaguchi T, Ando Y, et al. Interleukin-35 promotes the differentiation of regulatory T cells and suppresses Th2 response in IgG4-related type 1 autoimmune pancreatitis. J Gastroenterol. 2020;55:789-799 pubmed publisher
	Liu J, Hao S, Chen X, Zhao H, Du L, Ren H, et al. Human placental trophoblast cells contribute to maternal-fetal tolerance through expressing IL-35 and mediating iTR35 conversion. Nat Commun. 2019;10:4601 pubmed publisher
	Larousserie F, Kebe D, Huynh T, Audebourg A, Tamburini J, Terris B, et al. Evidence for IL-35 Expression in Diffuse Large B-Cell Lymphoma and Impact on the Patient's Prognosis. Front Oncol. 2019;9:563 pubmed publisher
	Javvadi L, Parachuru V, Milne T, Seymour G, Rich A. Expression of IL33 and IL35 in oral lichen planus. Arch Dermatol Res. 2018;310:431-441 pubmed publisher
	Zhao Z, Chen X, Hao S, Jia R, Wang N, Chen S, et al. Increased interleukin-35 expression in tumor-infiltrating lymphocytes correlates with poor prognosis in patients with breast cancer. Cytokine. 2017;89:76-81 pubmed publisher
	Horlad H, Ma C, Yano H, Pan C, Ohnishi K, Fujiwara Y, et al. An IL-27/Stat3 axis induces expression of programmed cell death 1 ligands (PD-L1/2) on infiltrating macrophages in lymphoma. Cancer Sci. 2016;107:1696-1704 pubmed publisher
	Long J, Guo H, Cui S, Zhang H, Liu X, Li D, et al. IL-35 expression in hepatocellular carcinoma cells is associated with tumor progression. Oncotarget. 2016;7:45678-45686 pubmed publisher
	Fu Y, Yi Y, Cai X, Sun J, Ni X, He H, et al. Overexpression of interleukin-35 associates with hepatocellular carcinoma aggressiveness and recurrence after curative resection. Br J Cancer. 2016;114:767-76 pubmed publisher
	Jaiswal A, Narayan S. Assembly of the base excision repair complex on abasic DNA and role of adenomatous polyposis coli on its functional activity. Biochemistry. 2011;50:1901-9 pubmed publisher
	Asagoshi K, Liu Y, Masaoka A, Lan L, Prasad R, Horton J, et al. DNA polymerase beta-dependent long patch base excision repair in living cells. DNA Repair (Amst). 2010;9:109-19 pubmed publisher
	Guo Z, Zheng L, Dai H, Zhou M, Xu H, Shen B. Human DNA polymerase beta polymorphism, Arg137Gln, impairs its polymerase activity and interaction with PCNA and the cellular base excision repair capacity. Nucleic Acids Res. 2009;37:3431-41 pubmed publisher
	Song W, Levin D, Varkey J, Post S, Bermudez V, Hurwitz J, et al. A conserved physical and functional interaction between the cell cycle checkpoint clamp loader and DNA ligase I of eukaryotes. J Biol Chem. 2007;282:22721-30 pubmed
	Windhofer F, Wu W, Iliakis G. Low levels of DNA ligases III and IV sufficient for effective NHEJ. J Cell Physiol. 2007;213:475-83 pubmed
	Rose J, Reeves K, Likhotvorik R, Hoyt D. Base excision repair proteins are required for integrin-mediated suppression of bleomycin-induced DNA breakage in murine lung endothelial cells. J Pharmacol Exp Ther. 2007;321:318-26 pubmed
	Wang W, Lindsey Boltz L, Sancar A, Bambara R. Mechanism of stimulation of human DNA ligase I by the Rad9-rad1-Hus1 checkpoint complex. J Biol Chem. 2006;281:20865-72 pubmed
	Wang H, Rosidi B, Perrault R, Wang M, Zhang L, Windhofer F, et al. DNA ligase III as a candidate component of backup pathways of nonhomologous end joining. Cancer Res. 2005;65:4020-30 pubmed
	Warren M, Lord C, Masabanda J, Griffin D, Ashworth A. Phenotypic effects of heterozygosity for a BRCA2 mutation. Hum Mol Genet. 2003;12:2645-56 pubmed
	Kao G, McKenna W, Guenther M, Muschel R, Lazar M, Yen T. Histone deacetylase 4 interacts with 53BP1 to mediate the DNA damage response. J Cell Biol. 2003;160:1017-27 pubmed
	Tarsounas M, Davies D, West S. BRCA2-dependent and independent formation of RAD51 nuclear foci. Oncogene. 2003;22:1115-23 pubmed
	French C, Masson J, Griffin C, O Regan P, West S, Thacker J. Role of mammalian RAD51L2 (RAD51C) in recombination and genetic stability. J Biol Chem. 2002;277:19322-30 pubmed publisher
	Masson J, Tarsounas M, Stasiak A, Stasiak A, Shah R, McIlwraith M, et al. Identification and purification of two distinct complexes containing the five RAD51 paralogs. Genes Dev. 2001;15:3296-307 pubmed
	Masson J, Davies A, Hajibagheri N, Van Dyck E, Benson F, Stasiak A, et al. The meiosis-specific recombinase hDmc1 forms ring structures and interacts with hRad51. EMBO J. 1999;18:6552-60 pubmed

product information

master code :

NBP2-27362

SKU :

NBP2-27362

product name :

EBI3 Antibody (15k8D10) - BSA Free

unit size :

0.1 mg (also 0.025 mg)

description :

The EBI3 Antibody (15k8D10) - BSA Free from Novus is a mouse monoclonal antibody to EBI3. This antibody reacts with human. The EBI3 Antibody (15k8D10) - BSA Free has been validated for the following applications: IF/IHC,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Western Blot,Tissue Culture Substratum.

target :

EBI3

category :

Primary Antibodies

buffer :

0.1 ml PBS

clonality :

Monoclonal

clone :

15k8D10

concentration :

1.0 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

A full-length human Interleukin-35-Fc fusion protein was used as immunogen for this antibody.

isotype :

IgG1 Kappa

purity :

Protein G purified

species :

Human

specificity :

The human Interleukin-35 protein is a dimeric protein consisting of the human IL-12a/p35 subunit (NP_000873

gene symbol :

EBI3

endotoxin note :

< 0.06 EU/ug

accessionNumbers :

NP_000873.2

applications :

IF/IHC,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Western Blot,Tissue Culture Substratum

USD :

399 USD

alt names :

cytokine receptor, EBV-induced gene 3 protein, Epstein-Barr virus induced 3, Epstein-Barr virus induced gene 3, Epstein-Barr virus-induced gene 3 protein, IL-27 subunit beta, IL27B, IL-27B, interleukin-27 subunit beta

storage :

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage