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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
TRAILR1/TNFRSF10A Antibody (32A1380) - Azide and BSA Free
catalog :
NBP2-27350
quantity :
0.1 mg
price :
459 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
32A1380
reactivity :
human
application :
western blot, neutralization, flow cytometry
more info or order :
Novus Biologicals product webpage
citations: 11
Reference
Park S, Cho D, Andera L, Suh N, Kim I. Curcumin enhances TRAIL-induced apoptosis of breast cancer cells by regulating apoptosis-related proteins. Mol Cell Biochem. 2013;383:39-48 pubmed publisher
Jane E, Premkumar D, Pollack I. Bortezomib sensitizes malignant human glioma cells to TRAIL, mediated by inhibition of the NF-{kappa}B signaling pathway. Mol Cancer Ther. 2011;10:198-208 pubmed publisher
Lin Y, Chen S, Yue P, Zou W, Benbrook D, Liu S, et al. CAAT/enhancer binding protein homologous protein-dependent death receptor 5 induction is a major component of SHetA2-induced apoptosis in lung cancer cells. Cancer Res. 2008;68:5335-44 pubmed publisher
Le Poole I, ElMasri W, Denman C, Kroll T, Bommiasamy H, Lyons Eiben G, et al. Langerhans cells and dendritic cells are cytotoxic towards HPV16 E6 and E7 expressing target cells. Cancer Immunol Immunother. 2008;57:789-97 pubmed
Tsurushima H, Yuan X, Dillehay L, Leong K. Radioresponsive tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) gene therapy for malignant brain tumors. Cancer Gene Ther. 2007;14:706-16 pubmed
Kroll T, Bommiasamy H, Boissy R, Hernandez C, Nickoloff B, Mestril R, et al. 4-Tertiary butyl phenol exposure sensitizes human melanocytes to dendritic cell-mediated killing: relevance to vitiligo. J Invest Dermatol. 2005;124:798-806 pubmed
Ren Y, Wagner K, Knee D, Aza Blanc P, Nasoff M, Deveraux Q. Differential regulation of the TRAIL death receptors DR4 and DR5 by the signal recognition particle. Mol Biol Cell. 2004;15:5064-74 pubmed
Liu X, Yue P, Khuri F, Sun S. p53 upregulates death receptor 4 expression through an intronic p53 binding site. Cancer Res. 2004;64:5078-83 pubmed
Chen X, Kandasamy K, Srivastava R. Differential roles of RelA (p65) and c-Rel subunits of nuclear factor kappa B in tumor necrosis factor-related apoptosis-inducing ligand signaling. Cancer Res. 2003;63:1059-66 pubmed
Guan B, Yue P, Lotan R, Sun S. Evidence that the human death receptor 4 is regulated by activator protein 1. Oncogene. 2002;21:3121-9 pubmed
Bretz J, Mezosi E, Giordano T, Gauger P, Thompson N, Baker J. Inflammatory cytokine regulation of TRAIL-mediated apoptosis in thyroid epithelial cells. Cell Death Differ. 2002;9:274-86 pubmed
product information
master code :
NBP2-27350
SKU :
NBP2-27350
product name :
TRAILR1/TNFRSF10A Antibody (32A1380) - Azide and BSA Free
unit size :
0.1 mg
description :
The TRAILR1/TNFRSF10A Antibody (32A1380) - Azide and BSA Free from Novus is a mouse monoclonal antibody to TRAILR1/TNFRSF10A. This antibody reacts with human. The TRAILR1/TNFRSF10A Antibody (32A1380) - Azide and BSA Free has been validated for the following applications: Flow - CS,Flow Cytometry Control,Flow Cytometry,Western Blot,Flow (Cell Surface),Flow (Intracellular),Simple Western,CyTOF-ready,Block/Neutralize.
target :
TRAILR1/TNFRSF10A
category :
Primary Antibodies
buffer :
PBS
clonality :
Monoclonal
clone :
32A1380
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Mouse
immunogen :
This monoclonal antibody was raised against a peptide corresponding to amino acid 2 to 21 of human DR4.
isotype :
IgG1 Kappa
purity :
Protein G purified
species :
Human
gene symbol :
TNFRSF10A
applications :
Flow - CS,Flow Cytometry Control,Flow Cytometry,Western Blot,Flow (Cell Surface),Flow (Intracellular),Simple Western,CyTOF-ready,Block/Neutralize
USD :
459 USD
alt names :
APO2, CD261, CD261 antigen, cytotoxic TRAIL receptor, Death receptor 4, DR4, DR4 TRAIL receptor 1, TNF-related apoptosis inducing ligand receptor 1, TNF-related apoptosis-inducing ligand receptor 1, TRAIL-R1, TRAILR-1, TRAILR1MGC9365, tumor necrosis factor receptor superfamily member 10A, tumor necrosis factor receptor superfamily, member 10a
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
Novus Biologicals product webpage
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.