product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
TLR7 Antibody (4G6) - BSA Free
catalog :
NBP2-27332
quantity :
0.1 mg (also 0.025 mg)
price :
449 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
4G6
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 31
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig 4l
Brown G, Ca xf1 ete P, Wang H, Medhavy A, Bones J, Roco J, et al. TLR7 gain-of-function genetic variation causes human lupus. Nature. 2022;605:349-356 pubmed publisher
  • immunocytochemistry; mouse
  • western blot; mouse
Priya R, Dhanwani R, Patro I, Rao P, Parida M. Differential regulation of TLR mediated innate immune response of mouse neuronal cells following infection with novel ECSA genotype of Chikungunya virus with and without E1:A226V mutation. Infect Genet Evol. 2013;20:396-406 pubmed publisher
Matic Girard I, Ward P, Durey A, Lund S, Calache H, Baker S, et al. Primary caregivers' perceptions of factors influencing preschool children's oral health: social practices perspective-a protocol for qualitative metasynthesis. BMJ Open. 2023;13:e068444 pubmed publisher
Wang Z, Sun Y, Lou F, Bai J, Zhou H, Cai X, et al. Targeting the transcription factor HES1 by L-menthol restores protein phosphatase 6 in keratinocytes in models of psoriasis. Nat Commun. 2022;13:7815 pubmed publisher
Lin T, Hu L, Hu F, Li K, Wang C, Zong L, et al. NET-Triggered NLRP3 Activation and IL18 Release Drive Oxaliplatin-Induced Peripheral Neuropathy. Cancer Immunol Res. 2022;10:1542-1558 pubmed publisher
Lam L, Dobkin J, Eckart K, Gereg I, DiSalvo A, Nolder A, et al. Bat Red Blood Cells Express Nucleic Acid-Sensing Receptors and Bind RNA and DNA. Immunohorizons. 2022;6:299-306 pubmed publisher
Wallach T, Mossmann Z, Szczepek M, Wetzel M, Machado R, Raden M, et al. MicroRNA-100-5p and microRNA-298-5p released from apoptotic cortical neurons are endogenous Toll-like receptor 7/8 ligands that contribute to neurodegeneration. Mol Neurodegener. 2021;16:80 pubmed publisher
Klammer M, Dzaye O, Wallach T, Krüger C, Gaessler D, Buonfiglioli A, et al. UNC93B1 Is Widely Expressed in the Murine CNS and Is Required for Neuroinflammation and Neuronal Injury Induced by MicroRNA let-7b. Front Immunol. 2021;12:715774 pubmed publisher
Kitaura A, Nishinaka T, Hamasaki S, Hatipoglu O, Wake H, Nishibori M, et al. Advanced glycation end-products reduce lipopolysaccharide uptake by macrophages. PLoS ONE. 2021;16:e0245957 pubmed publisher
Liao K, Niu F, Hu G, Yang L, Dallon B, Villarreal D, et al. Morphine-mediated release of miR-138 in astrocyte-derived extracellular vesicles promotes microglial activation. J Extracell Vesicles. 2020;10:e12027 pubmed publisher
Hagen S, Henseling F, Hennesen J, Savel H, Delahaye S, Richert L, et al. Heterogeneous Escape from X Chromosome Inactivation Results in Sex Differences in Type I IFN Responses at the Single Human pDC Level. Cell Rep. 2020;33:108485 pubmed publisher
Lou F, Sun Y, Xu Z, Niu L, Wang Z, Deng S, et al. Excessive Polyamine Generation in Keratinocytes Promotes Self-RNA Sensing by Dendritic Cells in Psoriasis. Immunity. 2020;53:204-216.e10 pubmed publisher
Luo Z, Su R, Wang W, Liang Y, Zeng X, Shereen M, et al. EV71 infection induces neurodegeneration via activating TLR7 signaling and IL-6 production. PLoS Pathog. 2019;15:e1008142 pubmed publisher
Noval Rivas M, Wakita D, Franklin M, Carvalho T, Abolhesn A, Gomez A, et al. Intestinal Permeability and IgA Provoke Immune Vasculitis Linked to Cardiovascular Inflammation. Immunity. 2019;51:508-521.e6 pubmed publisher
Odhams C, Roberts A, Vester S, Duarte C, Beales C, Clarke A, et al. Interferon inducible X-linked gene CXorf21 may contribute to sexual dimorphism in Systemic Lupus Erythematosus. Nat Commun. 2019;10:2164 pubmed publisher
Fujimoto T, Colbert L, Huang Y, Molkentine J, Deorukhkar A, Baseler L, et al. Selective EGLN Inhibition Enables Ablative Radiotherapy and Improves Survival in Unresectable Pancreatic Cancer. Cancer Res. 2019;79:2327-2338 pubmed publisher
Koupenova M, Corkrey H, Vitseva O, Manni G, Pang C, Clancy L, et al. The role of platelets in mediating a response to human influenza infection. Nat Commun. 2019;10:1780 pubmed publisher
Pich C, Meylan P, Mastelic Gavillet B, Nguyen T, Loyon R, Trang B, et al. Induction of Paracrine Signaling in Metastatic Melanoma Cells by PPARγ Agonist Rosiglitazone Activates Stromal Cells and Enhances Tumor Growth. Cancer Res. 2018;78:6447-6461 pubmed publisher
Wang X, Pan B, Honda G, Wang X, Hashimoto Y, Ohkawara H, et al. Cytoprotective and pro-angiogenic functions of thrombomodulin are preserved in the C loop of the fifth epidermal growth factor-like domain. Haematologica. 2018;103:1730-1740 pubmed publisher
Yanai H, Atsumi N, Tanaka T, Nakamura N, Komai Y, Omachi T, et al. Intestinal stem cells contribute to the maturation of the neonatal small intestine and colon independently of digestive activity. Sci Rep. 2017;7:9891 pubmed publisher
Tărlungeanu D, Deliu E, Dotter C, Kara M, Janiesch P, Scalise M, et al. Impaired Amino Acid Transport at the Blood Brain Barrier Is a Cause of Autism Spectrum Disorder. Cell. 2016;167:1481-1494.e18 pubmed publisher
Sharmin S, Taguchi A, Kaku Y, Yoshimura Y, Ohmori T, Sakuma T, et al. Human Induced Pluripotent Stem Cell-Derived Podocytes Mature into Vascularized Glomeruli upon Experimental Transplantation. J Am Soc Nephrol. 2016;27:1778-91 pubmed publisher
Tengroth L, Arebro J, Kumlien Geor n S, Winqvist O, Cardell L. Deprived TLR9 expression in apparently healthy nasal mucosa might trigger polyp-growth in chronic rhinosinusitis patients. PLoS ONE. 2014;9:e105618 pubmed publisher
Pippin J, Sparks M, Glenn S, Buitrago S, Coffman T, Duffield J, et al. Cells of renin lineage are progenitors of podocytes and parietal epithelial cells in experimental glomerular disease. Am J Pathol. 2013;183:542-57 pubmed publisher
Chauhan S, Singh V, Rai R, Rai M, Rai G. Distinct autoantibody profiles in systemic lupus erythematosus patients are selectively associated with TLR7 and TLR9 upregulation. J Clin Immunol. 2013;33:954-64 pubmed publisher
Pan S, Wu L, Chen C, Shieh S, Chiu H. Angiogenin expression in burn blister fluid: implications for its role in burn wound neovascularization. Wound Repair Regen. 2012;20:731-9 pubmed publisher
Lehmann S, Krüger C, Park B, Derkow K, Rosenberger K, Baumgart J, et al. An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration. Nat Neurosci. 2012;15:827-35 pubmed publisher
Ma L, Young J, Prabhala H, Pan E, Mestdagh P, Muth D, et al. miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis. Nat Cell Biol. 2010;12:247-56 pubmed publisher
Ran S, Downes A, Thorpe P. Increased exposure of anionic phospholipids on the surface of tumor blood vessels. Cancer Res. 2002;62:6132-40 pubmed
Mandriota S, Jussila L, Jeltsch M, Compagni A, Baetens D, Prevo R, et al. Vascular endothelial growth factor-C-mediated lymphangiogenesis promotes tumour metastasis. EMBO J. 2001;20:672-82 pubmed
Tanneau G, Hibrand Saint Oyant L, Chevaleyre C, Salmon H. Differential recruitment of T- and IgA B-lymphocytes in the developing mammary gland in relation to homing receptors and vascular addressins. J Histochem Cytochem. 1999;47:1581-92 pubmed
product information
master code :
NBP2-27332
SKU :
NBP2-27332
product name :
TLR7 Antibody (4G6) - BSA Free
unit size :
0.1 mg (also 0.025 mg)
description :
The TLR7 Antibody (4G6) - BSA Free from Novus is a mouse monoclonal antibody to TLR7. This antibody reacts with human,mouse. The TLR7 Antibody (4G6) - BSA Free has been validated for the following applications: Immunocytochemistry/ Immunofluorescence,Flow Cytometry,IF/IHC,Western Blot,Immunohistochemistry-Paraffin,Knockout Validated,Knockdown Validated,Immunohistochemistry,Flow (Intracellular),CyTOF-ready.
target :
TLR7
category :
Primary Antibodies
buffer :
PBS
clonality :
Monoclonal
clone :
4G6
concentration :
1 mg/ml
conjugate :
Unconjugated
host :
Mouse
immunogen :
A partial human TLR7 recombinant protein (amino acids 562-839) was used as the immunogen.
isotype :
IgG1 Kappa
purity :
Protein G purified
species :
Human,Mouse
gene symbol :
TLR7
applications :
Flow Cytometry,IF/IHC,Western Blot,Immunohistochemistry-Paraffin,Knockout Validated,Knockdown Validated,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Flow (Intracellular),CyTOF-ready
USD :
449 USD
alt names :
toll-like receptor 7
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.