B7-1/CD80 Antibody (62N3G8) - BSA Free | Novus Biologicals NBP2-25255 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

B7-1/CD80 Antibody (62N3G8) - BSA Free

catalog :

NBP2-25255

quantity :

0.1 mg (also 0.025 mg)

price :

409 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

62N3G8

reactivity :

human, mouse

application :

western blot, immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section

more info or order :

Novus Biologicals product webpage

citations: 18

Reference
Wu J, Jing X, Du Q, Sun X, Holgersson K, Gao J, et al. Disruption of the Clock Component Bmal1 in Mice Promotes Cancer Metastasis through the PAI-1-TGF-β-myoCAF-Dependent Mechanism. Adv Sci (Weinh). 2023;10:e2301505 pubmed publisher
Pokrývková B, Smahelova J, Dalewská N, Grega M, Vencalek O, Smahel M, et al. ARG1 mRNA Level Is a Promising Prognostic Marker in Head and Neck Squamous Cell Carcinomas. Diagnostics (Basel). 2021;11: pubmed publisher
Zhao Y, Lee C, Lin C, Gassen R, Xu X, Huang Z, et al. PD-L1:CD80 Cis-Heterodimer Triggers the Co-stimulatory Receptor CD28 While Repressing the Inhibitory PD-1 and CTLA-4 Pathways. Immunity. 2019;51:1059-1073.e9 pubmed publisher
Herrera M, Söderberg M, Sabirsh A, Valastro B, Mölne J, Santamaria B, et al. Inhibition of T-cell activation by the CTLA4-Fc Abatacept is sufficient to ameliorate proteinuric kidney disease. Am J Physiol Renal Physiol. 2017;312:F748-F759 pubmed publisher
Du X, Kazim A, Dawes I, Brown A, Yang H. The AAA ATPase VPS4/SKD1 regulates endosomal cholesterol trafficking independently of ESCRT-III. Traffic. 2013;14:107-19 pubmed publisher
Du X, Kazim A, Brown A, Yang H. An essential role of Hrs/Vps27 in endosomal cholesterol trafficking. Cell Rep. 2012;1:29-35 pubmed publisher
Luu W, Sharpe L, Stevenson J, Brown A. Akt acutely activates the cholesterogenic transcription factor SREBP-2. Biochim Biophys Acta. 2012;1823:458-64 pubmed publisher
Song B, DeBose Boyd R. Insig-dependent ubiquitination and degradation of 3-hydroxy-3-methylglutaryl coenzyme a reductase stimulated by delta- and gamma-tocotrienols. J Biol Chem. 2006;281:25054-61 pubmed
Song B, Javitt N, DeBose Boyd R. Insig-mediated degradation of HMG CoA reductase stimulated by lanosterol, an intermediate in the synthesis of cholesterol. Cell Metab. 2005;1:179-89 pubmed
Sun L, Li L, Goldstein J, Brown M. Insig required for sterol-mediated inhibition of Scap/SREBP binding to COPII proteins in vitro. J Biol Chem. 2005;280:26483-90 pubmed publisher
Adams C, Reitz J, De Brabander J, Feramisco J, Li L, Brown M, et al. Cholesterol and 25-hydroxycholesterol inhibit activation of SREBPs by different mechanisms, both involving SCAP and Insigs. J Biol Chem. 2004;279:52772-80 pubmed
Zhang Y, Hillgartner F. Starvation and feeding a high-carbohydrate, low-fat diet regulate the expression sterol regulatory element-binding protein-1 in chickens. J Nutr. 2004;134:2205-10 pubmed
Demoulin J, Ericsson J, Kallin A, Rorsman C, Ronnstrand L, Heldin C. Platelet-derived growth factor stimulates membrane lipid synthesis through activation of phosphatidylinositol 3-kinase and sterol regulatory element-binding proteins. J Biol Chem. 2004;279:35392-402 pubmed
Sever N, Yang T, Brown M, Goldstein J, DeBose Boyd R. Accelerated degradation of HMG CoA reductase mediated by binding of insig-1 to its sterol-sensing domain. Mol Cell. 2003;11:25-33 pubmed
Janowski B. The hypocholesterolemic agent LY295427 up-regulates INSIG-1, identifying the INSIG-1 protein as a mediator of cholesterol homeostasis through SREBP. Proc Natl Acad Sci U S A. 2002;99:12675-80 pubmed
Yabe D, Brown M, Goldstein J. Insig-2, a second endoplasmic reticulum protein that binds SCAP and blocks export of sterol regulatory element-binding proteins. Proc Natl Acad Sci U S A. 2002;99:12753-8 pubmed publisher
Yin L, Zhang Y, Hillgartner F. Sterol regulatory element-binding protein-1 interacts with the nuclear thyroid hormone receptor to enhance acetyl-CoA carboxylase-alpha transcription in hepatocytes. J Biol Chem. 2002;277:19554-65 pubmed
Janowski B, Shan B, Russell D. The hypocholesterolemic agent LY295427 reverses suppression of sterol regulatory element-binding protein processing mediated by oxysterols. J Biol Chem. 2001;276:45408-16 pubmed

product information

master code :

NBP2-25255

SKU :

NBP2-25255

product name :

B7-1/CD80 Antibody (62N3G8) - BSA Free

unit size :

0.1 mg (also 0.025 mg)

description :

The B7-1/CD80 Antibody (62N3G8) - BSA Free from Novus is a mouse monoclonal antibody to B7-1/CD80. This antibody reacts with human,mouse. The B7-1/CD80 Antibody (62N3G8) - BSA Free has been validated for the following applications: Western Blot,Immunohistochemistry-Paraffin,Flow Cytometry,Immunohistochemistry.

target :

B7-1/CD80

category :

Primary Antibodies

buffer :

PBS

clonality :

Monoclonal

clone :

62N3G8

concentration :

1.0 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

Amino acids 102-223 of human CD80 were used as the immunogen for the antibody.

isotype :

IgG2b Kappa

purity :

Protein G purified

species :

Human,Mouse

gene symbol :

CD80

accessionNumbers :

NP_005182

applications :

Western Blot,Immunohistochemistry-Paraffin,Flow Cytometry,Immunohistochemistry

USD :

409 USD

alt names :

Activation B7-1 antigen, B7, BB1, CD28LG1, CD28LGB7-1 antigen), CD80 antigen, CD80 molecule, costimulatory factor CD80, costimulatory molecule variant IgV-CD80, CTLA-4 counter-receptor B7.1, T-lymphocyte activation antigen CD80

storage :

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage