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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
B7-2/CD86 Antibody (BU63)
catalog :
NBP2-25208
quantity :
0.1 mg (also 0.02 mg)
price :
419 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
BU63
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, neutralization, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 36
Reference
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Shi C, Zhang Y, Wu G, Zhu Z, Zheng H, Sun X, et al. Hyaluronic Acid-Based Reactive Oxygen Species-Responsive Multifunctional Injectable Hydrogel Platform Accelerating Diabetic Wound Healing. Adv Healthc Mater. 2024;13:e2302626 pubmed publisher
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Chen S, Xing Z, Geng M, Zhao R, Yang X, Zhu X, et al. Macrophage fusion event as one prerequisite for inorganic nanoparticle-induced antitumor response. Sci Adv. 2023;9:eadd9871 pubmed publisher
Yao S, Zhou Z, Wang L, Lv H, Liu D, Zhu Q, et al. Targeting endometrial inflammation in intrauterine adhesion ameliorates endometrial fibrosis by priming MSCs to secrete C1INH. iScience. 2023;26:107201 pubmed publisher
Chen L, Song X, Yao Z, Zhou C, Yang J, Yang Q, et al. Gelatin nanofiber-reinforced decellularized amniotic membrane promotes axon regeneration and functional recovery in the surgical treatment of peripheral nerve injury. Biomaterials. 2023;300:122207 pubmed publisher
Tan X, Fang P, Li K, You M, Cao Y, Xu H, et al. A HER2-targeted antibody-novel DNA topoisomerase I inhibitor conjugate induces durable adaptive antitumor immunity by activating dendritic cells. MAbs. 2023;15:2220466 pubmed publisher
Ling Q, Fang J, Zhai C, Huang W, Chen Y, Zhou T, et al. Berberine induces SOCS1 pathway to reprogram the M1 polarization of macrophages via miR-155-5p in colitis-associated colorectal cancer. Eur J Pharmacol. 2023;949:175724 pubmed publisher
Jia X, Xie L, Liu Y, Liu T, Yang P, Hu J, et al. Astragalus polysaccharide (APS) exerts protective effect against acute ischemic stroke (AIS) through enhancing M2 micoglia polarization by regulating adenosine triphosphate (ATP)/ purinergic receptor (P2X7R) axis. Bioengineered. 2022;13:4468-4480 pubmed publisher
Luo Z, Xia K, Liu Y, Liu J, Rao S, Hu X, et al. Extracellular Vesicles from Akkermansia muciniphila Elicit Antitumor Immunity Against Prostate Cancer via Modulation of CD8+ T Cells and Macrophages. Int J Nanomedicine. 2021;16:2949-2963 pubmed publisher
Liu P, Peng C, Chen X, Wu L, Yin M, Li J, et al. Acitretin Promotes the Differentiation of Myeloid-Derived Suppressor Cells in the Treatment of Psoriasis. Front Med (Lausanne). 2021;8:625130 pubmed publisher
Yang D, Shen L, Chen R, Fu Y, Xu H, Zhang L, et al. The Effect of Talaromyces marneffei Infection on CD86 Expression in THP-1 Cells. Infect Drug Resist. 2021;14:651-660 pubmed publisher
Klinge U, Dievernich A, Tolba R, Klosterhalfen B, Davies L. CD68+ macrophages as crucial components of the foreign body reaction demonstrate an unconventional pattern of functional markers quantified by analysis with double fluorescence staining. J Biomed Mater Res B Appl Biomater. 2020;: pubmed publisher
Li M, Su X, Ren Y, Zhao X, Kong L, Kang J. HDAC8 inhibitor attenuates airway responses to antigen stimulus through synchronously suppressing galectin-3 expression and reducing macrophage-2 polarization. Respir Res. 2020;21:62 pubmed publisher
Shehata M, Saad Eldien H, Meligy F, Bahaidarh S. The Possible Protective Role of Barley Seeds on the Spleen after Administration of Glucocorticoids in Adult Albino Rats: A Histological and Immunohistochemical Study. J Microsc Ultrastruct. 2019;7:171-180 pubmed publisher
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Joly Amado A, Davtyan H, Serraneau K, Jules P, Zitnyar A, Pressman E, et al. Active immunization with tau epitope in a mouse model of tauopathy induced strong antibody response together with improvement in short memory and pSer396-tau pathology. Neurobiol Dis. 2020;134:104636 pubmed publisher
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Wang T, Xu Y, Yuan Y, Xu P, Zhang C, Li F, et al. Succinate induces skeletal muscle fiber remodeling via SUNCR1 signaling. EMBO Rep. 2019;20:e47892 pubmed publisher
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Li T, Hu J, Gao F, Du X, Chen Y, Wu Q. Transcription factors regulate GPR91-mediated expression of VEGF in hypoxia-induced retinopathy. Sci Rep. 2017;7:45807 pubmed publisher
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product information
master code :
NBP2-25208
SKU :
NBP2-25208
product name :
B7-2/CD86 Antibody (BU63)
unit size :
0.1 mg (also 0.02 mg)
description :
The B7-2/CD86 Antibody (BU63) from Novus is a mouse monoclonal antibody to B7-2/CD86. This antibody reacts with human,mouse,rat. The B7-2/CD86 Antibody (BU63) has been validated for the following applications: Western Blot,Immunocytochemistry/ Immunofluorescence,Simple Western,IF/IHC,Block/Neutralize,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunofluorescence,Flow Cytometry,Immunohistochemistry,Knockout Validated.
target :
B7-2/CD86
category :
Primary Antibodies
buffer :
10 mM PBS with 0.05% BSA
clonality :
Monoclonal
clone :
BU63
concentration :
0.2 mg/ml
conjugate :
Unconjugated
host :
Mouse
immunogen :
ARH-77 (B-lymphoblastoid cell line)
isotype :
IgG1 Kappa
purity :
Protein A or G purified
species :
Human,Mouse,Rat
theoretical molecular weight :
70 kDa
gene symbol :
CD86
Antibody validation :
Knockout/Knockdown
accessionNumbers :
NP_001193853, P42081, P42081
applications :
Immunocytochemistry/ Immunofluorescence,Simple Western,IF/IHC,Block/Neutralize,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunofluorescence,Flow Cytometry,Immunohistochemistry,Knockout Validated
extended description :
Clone BU63 was used by HLDA to establish CD designation.
USD :
419 USD
product details :
Clone BU63 was used by HLDA to establish CD designation.
alt names :
Activation B7-2 antigen, B70, B7-2, B7-2 antigen, B-lymphocyte activation antigen B7-2, BU63, CD28 antigen ligand 2, CD28LG2B7-2 antigen), CD86 antigen, CD86 molecule, CTLA-4 counter-receptor B7.2, FUN-1, LAB72, MGC34413, T-lymphocyte activation antigen CD86
storage :
Store at 4C.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.