product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
TLR7 Antibody - BSA Free
catalog :
NBP2-24906
quantity :
0.1 mg (also 0.025 mg)
price :
489 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
6H12
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, neutralization, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, proximity ligation assay, dot blot
more info or order :
citations: 49
Reference
Deng L, Gao R, Chen H, Jiao B, Zhang C, Wei L, et al. Let-7b-TLR7 Signaling Axis Contributes to the Anesthesia/Surgery-Induced Cognitive Impairment. Mol Neurobiol. 2024;61:1818-1832 pubmed publisher
Liu G, Haw T, Starkey M, Philp A, Pavlidis S, Nalkurthi C, et al. TLR7 promotes smoke-induced experimental lung damage through the activity of mast cell tryptase. Nat Commun. 2023;14:7349 pubmed publisher
Liu J, Ke P, Guo H, Gu J, Liu Y, Tian X, et al. Activation of TLR7-mediated autophagy increases epileptic susceptibility via reduced KIF5A-dependent GABAA receptor transport in a murine model. Exp Mol Med. 2023;55:1159-1173 pubmed publisher
Caccuri F, Messali S, Bortolotti D, Di Silvestre D, De Palma A, Cattaneo C, et al. Competition for dominance within replicating quasispecies during prolonged SARS-CoV-2 infection in an immunocompromised host. Virus Evol. 2022;8:veac042 pubmed publisher
Hayakawa K, Fujishiro M, Yoshida Y, Kataoka Y, Sakuma S, Nishi T, et al. Exposure of female NZBWF1 mice to imiquimod-induced lupus nephritis at an early age via a unique mechanism that differed from spontaneous onset. Clin Exp Immunol. 2022;208:33-46 pubmed publisher
Rouanet M, Hanoun N, Hubert Lulka -, Ferreira C, Garcin P, Srámek M, et al. The antitumoral activity of TLR7 ligands is corrupted by the microenvironment of pancreatic tumors. Mol Ther. 2022;30:1553-1563 pubmed publisher
Zhu Y, Wu Z, Yan W, Shao F, Ke B, Jiang X, et al. Allosteric inhibition of SHP2 uncovers aberrant TLR7 trafficking in aggravating psoriasis. EMBO Mol Med. 2022;14:e14455 pubmed publisher
Bortolotti D, Gentili V, Rizzo S, Schiuma G, Beltrami S, Strazzabosco G, et al. TLR3 and TLR7 RNA Sensor Activation during SARS-CoV-2 Infection. Microorganisms. 2021;9: pubmed publisher
Branchi V, Esser L, Boden C, Jafari A, Henn J, Lingohr P, et al. A Combined TLR7/TLR9/GATA3 Score Can Predict Prognosis in Biliary Tract Cancer. Diagnostics (Basel). 2021;11: pubmed publisher
Proskocil B, Wai K, Lebold K, Norgard M, Michaelis K, De La Torre U, et al. TLR7 is expressed by support cells, but not sensory neurons, in ganglia. J Neuroinflammation. 2021;18:209 pubmed publisher
Lin J, Li M, Wu T, Chang C. Combined methyl aminolevulinate-based photodynamic therapy and imiquimod in a patient with perianal extramammary Paget's disease. Photodiagnosis Photodyn Ther. 2021;35:102407 pubmed publisher
Zhang L, Luo H, Meng W, Cen Y, Huang Q, Li H, et al. Integration of Flow Cytometry and Computational Analysis to Dissect the Epidermal Cellular Subsets in Keloids that Correlate with Recurrence. J Invest Dermatol. 2021;: pubmed publisher
Qin L, Zou J, Barnett A, Vetreno R, Crews F, Coleman L. TRAIL Mediates Neuronal Death in AUD: A Link between Neuroinflammation and Neurodegeneration. Int J Mol Sci. 2021;22: pubmed publisher
Huang Y, Huang M, Sung P, Chou T, Yang R, Yang A, et al. Endosomal TLR3 co-receptor CLEC18A enhances host immune response to viral infection. Commun Biol. 2021;4:229 pubmed publisher
Zhang L, Cen Y, Huang Q, Li H, Mo X, Meng W, et al. Computational flow cytometric analysis to detect epidermal subpopulations in human skin. Biomed Eng Online. 2021;20:22 pubmed publisher
Agier J, Brzezińska Błaszczyk E, Witczak P, Kozłowska E, Żelechowska P. The impact of TLR7 agonist R848 treatment on mast cell phenotype and activity. Cell Immunol. 2021;359:104241 pubmed publisher
Karadimou G, Plunde O, Pawelzik S, Carracedo M, Eriksson P, Franco Cereceda A, et al. TLR7 Expression Is Associated with M2 Macrophage Subset in Calcific Aortic Valve Stenosis. Cells. 2020;9: pubmed publisher
Hoshikawa N, Sakai A, Takai S, Suzuki H. Targeting Extracellular miR-21-TLR7 Signaling Provides Long-Lasting Analgesia in Osteoarthritis. Mol Ther Nucleic Acids. 2020;19:199-207 pubmed publisher
Alshammari T, Alghamdi H, Green T, Niazy A, Alkahdar L, Alrasheed N, et al. Assessing the role of toll-like receptor in isolated, standard and enriched housing conditions. PLoS ONE. 2019;14:e0222818 pubmed publisher
Gu R, Huang T, Xiao J, Liao Z, Li J, Lan H, et al. The IRE1α Arm of UPR Regulates Muscle Cells Immune Characters by Restraining p38 MAPK Activation. Front Physiol. 2019;10:1198 pubmed publisher
Huang Y, Zhou F, Xiao Y, Shen C, Liu K, Zhao B. TLR7 mediates increased vulnerability to ischemic acute kidney injury in diabetes. Rev Assoc Med Bras (1992). 2019;65:1067-1073 pubmed publisher
Kasurinen A, Hagstrom J, Laitinen A, Kokkola A, Böckelman C, Haglund C. Evaluation of toll-like receptors as prognostic biomarkers in gastric cancer: high tissue TLR5 predicts a better outcome. Sci Rep. 2019;9:12553 pubmed publisher
Lanki M, Seppänen H, Mustonen H, Hagstrom J, Haglund C. Toll-like receptor 1 predicts favorable prognosis in pancreatic cancer. PLoS ONE. 2019;14:e0219245 pubmed publisher
Ruuskanen M, Leivo I, Minn H, Vahlberg T, Haglund C, Hagstrom J, et al. Expression of toll-like receptors in non-endemic nasopharyngeal carcinoma. BMC Cancer. 2019;19:624 pubmed publisher
Haeggblom L, Näsman A, Ramqvist T, Haglund C, Hagstrom J, Mäkitie A, et al. TLR5 and TLR7 are differentially expressed in human papillomavirus-positive and negative base of tongue squamous cell carcinoma, and TLR7 may have an independent prognostic influence. Acta Otolaryngol. 2019;139:206-210 pubmed publisher
Kapelouzou A, Kontogiannis C, Tsilimigras D, Georgiopoulos G, Kaklamanis L, Tsourelis L, et al. Differential expression patterns of Toll Like Receptors and Interleukin-37 between calcific aortic and mitral valve cusps in humans. Cytokine. 2019;116:150-160 pubmed publisher
Blanchard E, Loomis K, Bhosle S, Vanover D, Baumhof P, Pitard B, et al. Proximity Ligation Assays for In Situ Detection of Innate Immune Activation: Focus on In Vitro-Transcribed mRNA. Mol Ther Nucleic Acids. 2018;14:52-66 pubmed publisher
Sakata K, Nakayamada S, Miyazaki Y, Kubo S, Ishii A, Nakano K, et al. Up-Regulation of TLR7-Mediated IFN-α Production by Plasmacytoid Dendritic Cells in Patients With Systemic Lupus Erythematosus. Front Immunol. 2018;9:1957 pubmed publisher
Loomis K, Lindsay K, Zurla C, Bhosle S, Vanover D, Blanchard E, et al. In Vitro Transcribed mRNA Vaccines with Programmable Stimulation of Innate Immunity. Bioconjug Chem. 2018;29:3072-3083 pubmed publisher
Aravanis C, Kapelouzou A, Vagios S, Tsilimigras D, Katsimpoulas M, Moris D, et al. Toll-Like Receptors -2, -3, -4 and -7 Expression Patterns in the Liver of a CLP-Induced Sepsis Mouse Model. J Invest Surg. 2018;:1-9 pubmed publisher
Listyarifah D, Nieminen M, M xe4 kinen L, Haglund C, Grenier D, H xe4 yry V, et al. Treponema denticola chymotrypsin-like proteinase is present in early-stage mobile tongue squamous cell carcinoma and related to the clinicopathological features. J Oral Pathol Med. 2018;47:764-772 pubmed publisher
Murayama G, Furusawa N, Chiba A, Yamaji K, Tamura N, Miyake S. Enhanced IFN-? production is associated with increased TLR7 retention in the lysosomes of palasmacytoid dendritic cells in systemic lupus erythematosus. Arthritis Res Ther. 2017;19:234 pubmed publisher
Auger J, Santinón A, Roy D, Mossman K, Xu J, Segura M, et al. Type I Interferon Induced by Streptococcus suis Serotype 2 is Strain-Dependent and May Be Beneficial for Host Survival. Front Immunol. 2017;8:1039 pubmed publisher
Jouhi L, Mohamed H, Mäkitie A, Remes S, Haglund C, Atula T, et al. Toll-like receptor 5 and 7 expression may impact prognosis of HPV-positive oropharyngeal squamous cell carcinoma patients. Cancer Immunol Immunother. 2017;66:1619-1629 pubmed publisher
Feng Y, Zou L, Yan D, Chen H, Xu G, Jian W, et al. Extracellular MicroRNAs Induce Potent Innate Immune Responses via TLR7/MyD88-Dependent Mechanisms. J Immunol. 2017;199:2106-2117 pubmed publisher
To E, Vlahos R, Luong R, Halls M, Reading P, King P, et al. Endosomal NOX2 oxidase exacerbates virus pathogenicity and is a target for antiviral therapy. Nat Commun. 2017;8:69 pubmed publisher
Larsson O, Tengroth L, Xu Y, Uddman R, Kumlien Georén S, Cardell L. Substance P represents a novel first-line defense mechanism in the nose. J Allergy Clin Immunol. 2018;141:128-136.e3 pubmed publisher
Daley D, Zambirinis C, Seifert L, Akkad N, Mohan N, Werba G, et al. ?? T Cells Support Pancreatic Oncogenesis by Restraining ?? T Cell Activation. Cell. 2016;166:1485-1499.e15 pubmed publisher
Li X, Liu F, Zhang X, Shi G, Ren J, Ji J, et al. Notch-Hes-1 axis controls TLR7-mediated autophagic death of macrophage via induction of P62 in mice with lupus. Cell Death Dis. 2016;7:e2341 pubmed publisher
Huang A, Wu S. The effect of imiquimod on taste bud calcium transients and transmitter secretion. Br J Pharmacol. 2016;173:3121-3133 pubmed publisher
Zeng M, Nourishirazi E, Guinet E, Nouri Shirazi M. The genetic background influences the cellular and humoral immune responses to vaccines. Clin Exp Immunol. 2016;186:190-204 pubmed publisher
Jeon Y, Kim C, Koh J, Chung D, Ha G. Pellino-1 confers chemoresistance in lung cancer cells by upregulating cIAP2 through Lys63-mediated polyubiquitination. Oncotarget. 2016;7:41811-41824 pubmed publisher
Helley M, Abate W, Jackson S, Bennett J, Thompson S. The expression of Toll-like receptor 4, 7 and co-receptors in neurochemical sub-populations of rat trigeminal ganglion sensory neurons. Neuroscience. 2015;310:686-98 pubmed publisher
Renkonen J, Toppila Salmi S, Joenväärä S, Mattila P, Parviainen V, Hagström J, et al. Expression of Toll-like receptors in nasal epithelium in allergic rhinitis. APMIS. 2015;123:716-25 pubmed publisher
Renkonen S, Cardell L, Mattila P, Lundberg M, Haglund C, Hagström J, et al. Toll-like receptors 3, 7, and 9 in Juvenile nasopharyngeal angiofibroma. APMIS. 2015;123:439-44 pubmed publisher
Saito K, Kukita K, Kutomi G, Okuya K, Asanuma H, Tabeya T, et al. Heat shock protein 90 associates with Toll-like receptors 7/9 and mediates self-nucleic acid recognition in SLE. Eur J Immunol. 2015;45:2028-41 pubmed publisher
Jouhi L, Koljonen V, Böhling T, Haglund C, Hagström J. The expression of Toll-like receptors 2, 4, 5, 7 and 9 in Merkel cell carcinoma. Anticancer Res. 2015;35:1843-9 pubmed
Milara J, Morell A, Ballester B, Sanz C, Freire J, Qian X, et al. Roflumilast improves corticosteroid resistance COPD bronchial epithelial cells stimulated with toll like receptor 3 agonist. Respir Res. 2015;16:12 pubmed publisher
Mäkinen L, Atula T, Häyry V, Jouhi L, Datta N, Lehtonen S, et al. Predictive role of Toll-like receptors 2, 4, and 9 in oral tongue squamous cell carcinoma. Oral Oncol. 2015;51:96-102 pubmed publisher
product information
master code :
NBP2-24906
SKU :
NBP2-24906
product name :
TLR7 Antibody - BSA Free
unit size :
0.1 mg (also 0.025 mg)
description :
The TLR7 Antibody - BSA Free from Novus is a rabbit polyclonal antibody to TLR7. This antibody reacts with human,mouse,rat. The TLR7 Antibody - BSA Free has been validated for the following applications: Simple Western,Immunoprecipitation,Western Blot,Block/Neutralize,Cytometric Bead Assay Standard,Flow Cytometry Control,IF/IHC,Bioassay,Flow Cytometry,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Proximity Ligation Assay,Immunocytochemistry/ Immunofluorescence,Dot Blot,Flow (Intracellular),Bioactivity.
target :
TLR7
category :
Primary Antibodies
buffer :
PBS
clonality :
Polyclonal
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
Partial synthetic peptide made to an internal portion of the human TLR7 protein (between amino acids 700-750) [UniProt 9NYK1]
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human,Mouse,Rat
gene symbol :
TLR7
applications :
Simple Western,Immunoprecipitation,Western Blot,Block/Neutralize,Cytometric Bead Assay Standard,Flow Cytometry Control,IF/IHC,Bioassay,Flow Cytometry,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Proximity Ligation Assay,Immunocytochemistry/ Immunofluorescence,Dot Blot,Flow (Intracellular),Bioactivity
USD :
489 USD
alt names :
toll-like receptor 7
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.