This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Mouse Monoclonal TLR3 Antibody (40C1285.6) [PE]
catalog :
NBP2-24902
quantity :
0.1 ml
price :
369 USD
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
40C1285.6
reactivity :
human, mouse, dog
application :
immunocytochemistry, flow cytometry
citations: 21
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human
Tengroth L, Arebro J, Kumlien Geor n S, Winqvist O, Cardell L. Deprived TLR9 expression in apparently healthy nasal mucosa might trigger polyp-growth in chronic rhinosinusitis patients. PLoS ONE. 2014;9:e105618 pubmed publisher
Green T, Santos M, Ejaeidi A, Craft B, Lewis R, Cruse J. Toll-like receptor (TLR) expression of immune system cells from metastatic breast cancer patients with circulating tumor cells. Exp Mol Pathol. 2014;97:44-8 pubmed publisher
Østvik A, Granlund A, Torp S, Flatberg A, Beisvag V, Waldum H, et al. Expression of Toll-like receptor-3 is enhanced in active inflammatory bowel disease and mediates the excessive release of lipocalin 2. Clin Exp Immunol. 2013;173:502-11 pubmed publisher
Abdi J, Mutis T, Garssen J, Redegeld F. Characterization of the Toll-like receptor expression profile in human multiple myeloma cells. PLoS ONE. 2013;8:e60671 pubmed publisher
Yan K, Zhu W, Yu L, Li N, Zhang X, Liu P, et al. Toll-like receptor 3 and RIG-I-like receptor activation induces innate antiviral responses in mouse ovarian granulosa cells. Mol Cell Endocrinol. 2013;372:73-85 pubmed publisher
Pohar J, Pirher N, Bencina M, Mancek Keber M, Jerala R. The role of UNC93B1 protein in surface localization of TLR3 receptor and in cell priming to nucleic acid agonists. J Biol Chem. 2013;288:442-54 pubmed publisher
Yamashita M, Chattopadhyay S, Fensterl V, Saikia P, Wetzel J, Sen G. Epidermal growth factor receptor is essential for Toll-like receptor 3 signaling. Sci Signal. 2012;5:ra50 pubmed publisher
Kleinman M, Kaneko H, Cho W, Dridi S, Fowler B, Blandford A, et al. Short-interfering RNAs induce retinal degeneration via TLR3 and IRF3. Mol Ther. 2012;20:101-8 pubmed publisher
Kuznik A, Bencina M, Svajger U, Jeras M, Rozman B, Jerala R. Mechanism of endosomal TLR inhibition by antimalarial drugs and imidazoquinolines. J Immunol. 2011;186:4794-804 pubmed publisher
Dasgupta G, Chentoufi A, You S, Falatoonzadeh P, Urbano L, Akhtarmalik A, et al. Engagement of TLR2 reverses the suppressor function of conjunctiva CD4+CD25+ regulatory T cells and promotes herpes simplex virus epitope-specific CD4+CD25- effector T cell responses. Invest Ophthalmol Vis Sci. 2011;52:3321-33 pubmed publisher
Johnston M, Wang A, Catarino M, Ball L, Phan V, MacDonald J, et al. Extracts of the rat tapeworm, Hymenolepis diminuta, suppress macrophage activation in vitro and alleviate chemically induced colitis in mice. Infect Immun. 2010;78:1364-75 pubmed publisher
Ménager P, Roux P, Mégret F, Bourgeois J, Le Sourd A, Danckaert A, et al. Toll-like receptor 3 (TLR3) plays a major role in the formation of rabies virus Negri Bodies. PLoS Pathog. 2009;5:e1000315 pubmed publisher
Sacre S, Lo A, Gregory B, Simmonds R, Williams L, Feldmann M, et al. Inhibitors of TLR8 reduce TNF production from human rheumatoid synovial membrane cultures. J Immunol. 2008;181:8002-9 pubmed
Cohen P, Koski G, Czerniecki B, Bunting K, Fu X, Wang Z, et al. STAT3- and STAT5-dependent pathways competitively regulate the pan-differentiation of CD34pos cells into tumor-competent dendritic cells. Blood. 2008;112:1832-43 pubmed publisher
Burgener I, Jungi T. Antibodies specific for human or murine Toll-like receptors detect canine leukocytes by flow cytometry. Vet Immunol Immunopathol. 2008;124:184-91 pubmed publisher
Wong C, Cheung P, Ip W, Lam C. Intracellular signaling mechanisms regulating toll-like receptor-mediated activation of eosinophils. Am J Respir Cell Mol Biol. 2007;37:85-96 pubmed
Ranjith Kumar C, Miller W, Xiong J, Russell W, Lamb R, Santos J, et al. Biochemical and functional analyses of the human Toll-like receptor 3 ectodomain. J Biol Chem. 2007;282:7668-78 pubmed
Xu S, Koldovsky U, Xu M, Wang D, Fitzpatrick E, Son G, et al. High-avidity antitumor T-cell generation by toll receptor 8-primed, myeloid- derived dendritic cells is mediated by IL-12 production. Surgery. 2006;140:170-8 pubmed
Mansson A, Adner M, Cardell L. Toll-like receptors in cellular subsets of human tonsil T cells: altered expression during recurrent tonsillitis. Respir Res. 2006;7:36 pubmed
Francois S, El Benna J, Dang P, Pedruzzi E, Gougerot Pocidalo M, Elbim C. Inhibition of neutrophil apoptosis by TLR agonists in whole blood: involvement of the phosphoinositide 3-kinase/Akt and NF-kappaB signaling pathways, leading to increased levels of Mcl-1, A1, and phosphorylated Bad. J Immunol. 2005;174:3633-42 pubmed
Funami K, Matsumoto M, Oshiumi H, Akazawa T, Yamamoto A, Seya T. The cytoplasmic 'linker region' in Toll-like receptor 3 controls receptor localization and signaling. Int Immunol. 2004;16:1143-54 pubmed
product information
Catalog Number :
NBP2-24902
Product Name :
Mouse Monoclonal TLR3 Antibody (40C1285.6) [PE]
List Price :
369 USD
product type :
Primary Antibodies
Package Size :
0.1 ml
AltNames :
CD283, CD283 antigen, toll-like receptor 3
Buffer :
PBS
Clonality :
Monoclonal
Clone :
40C1285.6
Conjugate :
PE
Application Summary :
Flow (Intracellular), Flow Cytometry, Immunocytochemistry/Immunofluorescence
Host :
Mouse
Immunogen :
A synthetic peptide corresponding to amino acids 55-85 of human TLR3 was used as immunogen.
Isotype :
IgG1 Kappa
Preservative :
0.05% Sodium Azide
Purity :
Protein G purified
CrossReactivity :
Canine, Human, Mouse
Storage :
Store at 4C in the dark.
Swissprot Human :
O15455
Uses :
Use in Flow Intracellular reported in scientific literature (PMID 24836676)
Research Area :
Cytokine Research, Immune System Diseases, Immunology, Innate Immunity, Signal Transduction, Toll Like Receptors
company information
Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
novus@novusbio.com
www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.